Patents
US 12502672 B2: Vascular flow-based microfluidic platform
- Granted
- 2025-12-23
- Filed
- 2020-04-08 application 17601745
- Type
- Utility · 27 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Described herein is a microfluidic assay device that mimics in vitro the in vivo biological environment, supporting endothelization, allowing for perfusive flow similar to in vivo blood flow conditions, and providing for realistic interactions between T-cells and solid tumor cells, such as glioblastoma multiforme tumor cells. Also described herein are methods of using this microfluidic assay device for the study of interactions of immune cells with tumor cells, such as glioblastoma multiforme tumor cells, and the development of improved immunotherapeutic approaches against cancers, such as glioblastoma multiforme.
Source: PVGPATDIS, file of 2026-04-10 (ipg251223.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 535 patents | US company or organization | Athens, GA | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. State business registration EXACT high confidence: identical full name and state UNIVERSITY OF GEORGIA RESEARCH FOUNDATION INC Nonprofit EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Lohitash Karumbaiah | Bogart, GA | 2 | PVGPATDIS, file of 2026-04-10 | |
| Meghan T. Logun | Marietta, GA | 2 | PVGPATDIS, file of 2026-04-10 | |
| Leidong Mao | Watkinsville, GA | 9 | PVGPATDIS, file of 2026-04-10 | |
| Wujun Zhao | Waunakee, WI | 4 | PVGPATDIS, file of 2026-04-10 | |
| Yang Liu | Bogart, GA | 111 | PVGPATDIS, file of 2026-04-10 | |
| Chaitanya Tondepu | San Francisco, CA | 1 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| B01L | Chemical or physical laboratory apparatus for general use | B01L3/502761 | PVGPATDIS, file of 2026-04-10 |
| G01N | Investigating or analysing materials by determining their chemical or physical properties | G01N33/5091 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2024-02-12 | Assignment Assignment of assignor's interest | TONDEPU, CHAITANYA signed 2024-01-03 ZHAO, WUJUN signed 2024-01-03 MAO, LEIDONG signed 2024-01-10 LIU, YANG signed 2024-02-09 LOGUN, MEGHAN TAYLOR signed 2024-02-09 | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. ATHENS, GA | 66445/497 | ECORSEXC, file of 2026-09-25 |
| 2022-07-13 | Assignment Assignment of assignor's interest | KARUMBAIAH, LOHITASH signed 2020-08-14 | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. ATHENS, GA | 60499/422 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.