Patents
US 12502442 B2: Structural optimization method to improve the theranostic performance of peptide receptor-targeted radionuclide therapy for cancers
- Granted
- 2025-12-23
- Filed
- 2021-01-28 application 17795792
- Type
- Utility · 3 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present invention provides in certain embodiments a carcinoma-targeting conjugate comprising Formula I wherein T is a SST2R targeting ligand, L is a linker, and X is a chelator, for the therapeutic treatment of cancer, and methods of use thereof.
Source: PVGPATDIS, file of 2026-04-10 (ipg251223.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| University of Iowa Research Foundation 401 patents | US company or organization | Iowa City, IA | UNIVERSITY OF IOWA RESEARCH FOUNDATION Nonprofit EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Dongyoul Lee | Iowa City, IA | 4 | PVGPATDIS, file of 2026-04-10 | |
| Michael K. Schultz | Iowa City, IA | 15 | PVGPATDIS, file of 2026-04-10 | |
| Mengshi Li | Iowa City, IA | 5 | PVGPATDIS, file of 2026-04-10 | |
| Nicholas Baumhover | Iowa City, IA | 3 | PVGPATDIS, file of 2026-04-10 | |
| F. Christoper Pigge | Iowa City, IA | 1 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K51/1096 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P35/00 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2025-01-07 | Assignment Assignment of assignor's interest | SCHULTZ, MICHAEL K. signed 2020-03-05 LEE, DONGYOUL signed 2020-03-06 BAUMHOVER, NICHOLAS signed 2020-03-09 LI, MENGSHI signed 2020-03-09 PIGGE, F. CHRISTOPHER signed 2020-03-10 | UNIVERSITY OF IOWA RESEARCH FOUNDATION IOWA CITY, IA | 69767/98 | ECORSEXC, file of 2026-09-25 |
| 2024-08-13 | Other License | UNIVERSITY OF IOWA signed 2023-03-01 | NATIONAL INSTITUTES OF HEALTH BETHESDA, MD | 68568/161 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.