Patents
US 12486300 B2: Mithramycin oxime derivatives having increased selectivity and anti-cancer activity
- Granted
- 2025-12-02
- Filed
- 2022-10-11 application 17963537
- Type
- Utility · 12 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Compounds described herein are mithramycin (MTM) oxide (OX) derivatives. These compounds are useful for treatment of cancers and neuro-diseases.
Source: PVGPATDIS, file of 2026-04-10 (ipg251202.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 446 patents | US company or organization | Lexington, KY | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION Nonprofit EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Jon S. Thorson | Lexington, KY | 22 | PVGPATDIS, file of 2026-04-10 | |
| Jurgen Rohr | Lexington, KY | 6 | PVGPATDIS, file of 2026-04-10 | |
| Markos Leggas | Lexington, KY | 6 | PVGPATDIS, file of 2026-04-10 | |
| Joseph Eckenrode | Lexington, KY | 4 | PVGPATDIS, file of 2026-04-10 | |
| Yinan Zhang | 安丰镇, CN | 22 | PVGPATDIS, file of 2026-04-10 | |
| Yang Liu | Lexington, KY | 111 | PVGPATDIS, file of 2026-04-10 | |
| Jianjun Zhang | Lexington, KY | 97 | PVGPATDIS, file of 2026-04-10 | |
| Khaled Attia Shaaban Mahmoud | Lexington, KY | 2 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07H | Sugars; derivatives thereof; nucleosides; nucleotides; nucleic acids | C07H15/244 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P35/00 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2022-10-11 | Assignment Assignment of assignor's interest | ECKENRODE, JOSEPH signed 2020-05-07 LIU, YANG signed 2020-05-07 ROHR, JURGEN T signed 2020-05-07 THORSON, JON S signed 2020-05-07 ZHANG, JIANJUN signed 2020-05-07 SHAABAN MAHMOUD, KHALED ATTIA signed 2020-05-08 ZHANG, YINAN signed 2020-05-08 LEGGAS, MARKOS signed 2020-05-11 | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION LEXINGTON, KY | 61379/37 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.