Patents
US 12482098 B2: Plaque detection method for imaging of cells
- Granted
- 2025-11-25
- Filed
- 2022-02-01 application 18275171
- Type
- Utility · 11 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
A plaque detection method and apparatus wherein at least one processor is programmed to receive above focus images to detect the presence of live cells without detecting the lysed cell materials, receive below focus images wherein virtual dark regions exist which are similar to cell shadows as seeds in a segmentation process and use contours around each resulting shape to obtain a subset that are more likely to be part of the cell population to define a cell map. A distance map is created in which each pixel value is the distance of that pixel from the nearest pixel of the cell map and the distance map is thresholded to create a first image of the places which are relatively far from the cells a second image with a smaller distance threshold to get an image that mimics the edges of the cells.
Source: PVGPATDIS, file of 2026-04-10 (ipg251125.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Thrive Bioscience, Inc. 38 patents | US company or organization | Beverly, MA | THRIVE BIOSCIENCE, INC. State business registration EXACT high confidence: identical full name and state Thrive Bioscience, Inc. Form D issuer EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Kenneth W. Chapman | Winscott, TX | 19 | PVGPATDIS, file of 2026-04-10 | |
| Frank G. Evans | Portland, OR | 5 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C12M | Apparatus for enzymology or microbiology; apparatus for culturing microorganisms for producing biomass, for growing cells or for obtaining fermentation or metabolic products, i.e. bioreactors or fermenters | C12M41/36 | PVGPATDIS, file of 2026-04-10 |
| G06T | Image data processing or generation, in general | G06T7/0012 | PVGPATDIS, file of 2026-04-10 |
| G01N | Investigating or analysing materials by determining their chemical or physical properties | G01N15/06 | PVGPATDIS, file of 2026-04-10 |
| G03H | Holographic processes or apparatus | G03H1/0866 | PVGPATDIS, file of 2026-04-10 |
| G06V | Image or video recognition or understanding | G06V10/50 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2023-08-01 | Assignment Assignment of assignor's interest | CHAPMAN, KENNETH W. signed 2023-08-01 EVANS, FRANK signed 2023-08-01 | THRIVE BIOSCIENCE, INC. WAKEFIELD, MA | 64450/921 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.