Patents
US 12474342 B2: Methods for treating cancer and the use of biomarkers as a predictor of clinical sensitivity to therapies
- Granted
- 2025-11-18
- Filed
- 2022-08-05 application 17882278
- Type
- Utility · 25 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
A method of identifying a subject having cancer who is likely to be responsive to a treatment compound, comprising administering the treatment compound to the subject having the cancer; obtaining a sample from the subject; determining the level of a biomarker in the sample from the subject; and diagnosing the subject as being likely to be responsive to the treatment compound if the level of the biomarker in the sample of the subject changes as compared to a reference level of the biomarker; wherein the treatment compound is a compound of Formula I:
Source: PVGPATDIS, file of 2026-04-10 (ipg251118.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Celgene Corporation 413 patents | US company or organization | Summit, NJ | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Ellen Filvaroff | San Francisco, CA | 20 | PVGPATDIS, file of 2026-04-10 | |
| Antonia Lopez-Girona | San Diego, CA | 38 | PVGPATDIS, file of 2026-04-10 | |
| Gang Lu | San Diego, CA | 75 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| G01N | Investigating or analysing materials by determining their chemical or physical properties | G01N33/575 | PVGPATDIS, file of 2026-04-10 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K31/454 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P35/00 | PVGPATDIS, file of 2026-04-10 |
| C12Q | Measuring or testing processes involving enzymes, nucleic acids or microorganisms ; compositions or test papers therefor; processes of preparing such compositions; condition-responsive control in microbiological or enzymological processes | C12Q1/6886 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2025-09-24 | Assignment Assignment of assignor's interest | FILVAROFF, ELLEN signed 2016-12-19 LU, GANG signed 2017-01-04 LOPEZ-GIRONA, ANTONIA signed 2017-01-05 | CELGENE CORPORATION SUMMIT, NJ | 72368/280 | ECORSEXC, file of 2026-09-25 |
| 2025-09-24 | Assignment Assignment of assignor's interest | LOPEZ-GIRONA, ANTONIA signed 2016-07-07 LU, GANG signed 2016-07-07 FILVAROFF, ELLEN signed 2016-07-18 | CELGENE CORPORATION SUMMIT, NJ | 72368/250 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.