Patents

US 12472176 B2: Pharmaceutical compositions comprising (S)-4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl)benzyl)piperazin-1-yl)-3-fluorobenzonitrile and methods of using the same

Granted
2025-11-18
Filed
2021-07-06 application 18014882
Type
Utility · 22 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

Provided herein are pharmaceutical compositions (e.g., oral dosage formulations) comprising (S)-4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl)benzyl)piperazin-1-yl)-3-fluorobenzonitrile, or an enantiomer, mixture of enantiomers, tautomer, isotopolog, or pharmaceutically acceptable salt thereof, and a carrier or diluent. Also provided herein are methods of preparing and methods of using the pharmaceutical compositions.

Source: PVGPATDIS, file of 2026-04-10 (ipg251118.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
Celgene Corporation 413 patentsUS company or organizationSummit, NJPVGPATDIS, file of 2026-04-10

Inventors

InventorPlacePatentsPerson pageSource
Anjali AgrawalJalan Pedongkelan, NJ3PVGPATDIS, file of 2026-04-10
Biplob K. MITRAJalan Pedongkelan, NJ1PVGPATDIS, file of 2026-04-10
Prajwal Gunwanth ThoolShort Hills, NJ3PVGPATDIS, file of 2026-04-10
Shannon Higgins-GruberScotch Plains, NJ1PVGPATDIS, file of 2026-04-10
Jennifer Almodovar RodriguezCranford, NJ1PVGPATDIS, file of 2026-04-10
Demin LiuBerkeley Heights, NJ7PVGPATDIS, file of 2026-04-10

CPC categories

SubclassCategoryFirst groupSource
A61KPreparations for medical, dental or toiletry purposesA61K9/1623PVGPATDIS, file of 2026-04-10
A61PSpecific therapeutic activity of chemical compounds or medicinal preparationsA61P1/00PVGPATDIS, file of 2026-04-10

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

RecordedWhatFromToReel/frameSource
2023-06-30Assignment
Assignment of assignor's interest
AGRAWAL, ANJALI signed 2020-12-13
MITRA, BIPLOB K. signed 2020-12-11
THOOL, PRAJWAL GUNWANTH signed 2021-07-01
HIGGINS-GRUBER, SHANNON signed 2021-07-01
RODRIGUEZ, JENNIFER ALMODOVAR signed 2021-07-01
LIU, DEMIN signed 2021-07-01
CELGENE CORPORATION SUMMIT, NJ64133/694PASDL, file of 2026-10-15

Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.