Patents
US 12442020 B2: Materials and methods for treatment of pain related disorders
- Granted
- 2025-10-14
- Filed
- 2022-10-03 application 17959089
- Type
- Utility · 18 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present application provides materials and methods for treating a patient with one or more conditions associated with SCN9A whether ex vivo or in vivo. In addition, the present application provides materials and methods for editing and/or modulating the expression of SCN9A gene in a cell by genome editing.
Source: PVGPATDIS, file of 2026-04-10 (ipg251014.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Vertex Pharmaceuticals Incorporated 764 patents | US company or organization | Boston, MA | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Ante Sven Lundberg | Cambridge, MA | 18 | PVGPATDIS, file of 2026-04-10 | |
| Samarth Kulkarni | Cambridge, MA | 10 | PVGPATDIS, file of 2026-04-10 | |
| Lawrence Klein | Cambridge, MA | 35 | PVGPATDIS, file of 2026-04-10 | |
| Hari Kumar Padmanabhan | Cambridge, MA | 12 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N15/907 | PVGPATDIS, file of 2026-04-10 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K35/30 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P25/04 | PVGPATDIS, file of 2026-04-10 |
| C07K | Peptides | C07K14/705 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2023-02-03 | Assignment Assignment of assignor's interest | CRISPR THERAPEUTICS AG signed 2019-12-04 | VERTEX PHARMACEUTICALS INCORPORATED BOSTON, MA | 62584/745 | ECORSEXC, file of 2026-09-25 |
| 2023-02-03 | Assignment Assignment of assignor's interest | PADMANABHAN, HARI KUMAR signed 2017-12-13 KLEIN, LAWRENCE signed 2017-12-14 KULKARNI, SAMARTH signed 2017-12-14 LUNDBERG, ANTE SVEN signed 2017-12-14 | CRISPR THERAPEUTICS AG ZUG | 62584/658 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.