Patents
US 12440481 B2: Esters and carbamates as modulators of sodium channels
- Granted
- 2025-10-14
- Filed
- 2020-01-09 application 17421945
- Type
- Utility · 23 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
Source: PVGPATDIS, file of 2026-04-10 (ipg251014.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Vertex Pharmaceuticals Incorporated 764 patents | US company or organization | Boston, MA | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Stephen Andrew Thomson | Del Mar, CA | 16 | PVGPATDIS, file of 2026-04-10 | |
| Nadia Ahmad | East Hagbourne, GB | 24 | PVGPATDIS, file of 2026-04-10 | |
| Corey Anderson | Watertown, MA | 55 | PVGPATDIS, file of 2026-04-10 | |
| Vijayalaksmi Arumugam | San Marcos, CA | 40 | PVGPATDIS, file of 2026-04-10 | |
| Iuliana Luci Asgian | San Diego, CA | 15 | PVGPATDIS, file of 2026-04-10 | |
| Joanne Louise Camp | East Hagbourne, GB | 5 | PVGPATDIS, file of 2026-04-10 | |
| Lev Tyler Dewey Fanning | San Marcos, CA | 22 | PVGPATDIS, file of 2026-04-10 | |
| Sara S. Hadida Ruah | Lake Davis, CA | 86 | PVGPATDIS, file of 2026-04-10 | |
| Dennis James Hurley | San Marcos, CA | 40 | PVGPATDIS, file of 2026-04-10 | |
| Yvonne Schmidt | San Diego, CA | 11 | PVGPATDIS, file of 2026-04-10 | |
| David Matthew Shaw | North Hinksey, GB | 24 | PVGPATDIS, file of 2026-04-10 | |
| Urvi Patel | San Diego, CA | 5 | PVGPATDIS, file of 2026-04-10 | |
| Lidio Marx Carvalho Meireles | San Marcos, CA | 11 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K31/44 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P29/00 | PVGPATDIS, file of 2026-04-10 |
| C07C | Acyclic or carbocyclic compounds | C07C65/24 | PVGPATDIS, file of 2026-04-10 |
| C07D | Heterocyclic compounds | C07D213/56 | PVGPATDIS, file of 2026-04-10 |
| C07B | General methods of organic chemistry; apparatus therefor | C07B2200/05 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2025-06-20 | Assignment Assignment of assignor's interest | VERTEX PHARMACEUTICALS (SAN DIEGO) LLC signed 2025-06-17 | VERTEX PHARMACEUTICALS INCORPORATED BOSTON, MA | 71462/680 | ECORSEXC, file of 2026-09-25 |
| 2025-06-20 | Assignment Assignment of assignor's interest | ANDERSON, COREY signed 2025-04-22 ASGIAN, IULIANA LUCI signed 2025-05-06 HURLEY, DENNIS signed 2025-05-06 PATEL, URVI signed 2025-05-07 FANNING, LEV TYLER DEWEY signed 2025-05-27 HADIDA RUAH, SARA SABINA signed 2025-05-28 ARUMUGAM, VIJAYALAKSMI signed 2025-06-11 SCHMIDT, YVONNE signed 2025-06-11 | VERTEX PHARMACEUTICALS (SAN DIEGO) LLC SAN DIEGO, CA | 71462/608 | ECORSEXC, file of 2026-09-25 |
| 2025-06-20 | Assignment Assignment of assignor's interest | VERTEX PHARMACEUTICALS (EUROPE) LIMITED signed 2025-06-17 | VERTEX PHARMACEUTICALS INCORPORATED BOSTON, MA | 71462/465 | ECORSEXC, file of 2026-09-25 |
| 2025-06-20 | Assignment Assignment of assignor's interest | AHMAD, NADIA signed 2025-04-10 CAMP, JOANNE LOUISE signed 2025-04-23 SHAW, DAVID signed 2025-04-30 | VERTEX PHARMACEUTICALS (EUROPE) LIMITED LONDON | 71462/425 | ECORSEXC, file of 2026-09-25 |
| 2025-06-20 | Assignment Assignment of assignor's interest | CARVALHO MEIRELES, LIDIO MARX signed 2025-04-07 | VERTEX PHARMACEUTICALS INCORPORATED BOSTON, MA | 71462/301 | ECORSEXC, file of 2026-09-25 |
| 2021-08-06 | Assignment Assignment of assignor's interest | THOMSON, STEPHEN ANDREW signed 2021-07-24 | VERTEX PHARMACEUTICALS INCORPORATED BOSTON, MA | 57102/904 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.