Patents
US 12428648 B2: Compositions comprising peptides that block transmission of orthotospoviruses
- Granted
- 2025-09-30
- Filed
- 2023-03-06 application 18117995
- Type
- Utility · 20 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Orthotospovirus virions travel through the thrips foregut and enter midgut epithelial cells through the interaction between virus glycoproteins and cellular receptors with several protein motifs thought to be involved in the interaction. Single, double and triple mutant polypeptides in the soybean vein necrosis virus (SVNV)/Neohydatothrips variabilis system are provided herein and several are shown to block viral transmission from the thrips to the soybean plants. Methods for inhibiting viral transmission using these polypeptides or constructs comprising polynucleotides encoding peptides are also provided herein.
Source: PVGPATDIS, file of 2026-04-10 (ipg250930.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS 225 patents | US company or organization | Little Rock, AR | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Ioannis Tzanetakis | Fayetteville, AR | 2 | PVGPATDIS, file of 2026-04-10 | |
| Jing Zhou | Greenbelt, MD | 13 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N15/8283 | PVGPATDIS, file of 2026-04-10 |
| C07K | Peptides | C07K7/08 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2023-05-10 | Assignment Assignment of assignor's interest | TZANETAKIS, IOANNIS signed 2019-07-22 ZHOU, JING signed 2019-07-23 | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS LITTLE ROCK, AR | 63605/953 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.