Patents

US 12403179 B2: Release of growth factors at wound healing stages

Granted
2025-09-02
Filed
2022-02-18 application 17675762
Type
Utility · 6 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

The present invention provides collagen-binding agents that can be used to treat wounds, ischemic heart disease, and other conditions. The collagen-binding agents comprise a therapeutic agent, a protease cleavage site, and a collagen-binding domain. The present invention further provides pharmaceutical compositions and biomedical devices comprising the disclosed collagen-binding agents, as well as methods for treating a condition using the collagen-binding agents.

Source: PVGPATDIS, file of 2026-04-10 (ipg250902.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS 225 patentsUS company or organizationLittle Rock, ARPVGPATDIS, file of 2026-04-10
NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY 118 patentsForeign company or organizationOkayama, JPPVGPATDIS, file of 2026-04-10

Inventors

InventorPlacePatentsPerson pageSource
Joshua SakonFayetteville, AR15PVGPATDIS, file of 2026-04-10
Robert BeitleFayetteville, AR11PVGPATDIS, file of 2026-04-10
Hazim AljewariFayetteville, AR1PVGPATDIS, file of 2026-04-10
Osamu MatsushitaOkayama, JP14PVGPATDIS, file of 2026-04-10
Stephanie BeitleFayetteville, AR1PVGPATDIS, file of 2026-04-10

CPC categories

SubclassCategoryFirst groupSource
A61KPreparations for medical, dental or toiletry purposesA61K38/1825PVGPATDIS, file of 2026-04-10
A61LMethods or apparatus for sterilising materials or objects in general; disinfection, sterilisation or deodorisation of air; chemical aspects of bandages, dressings, absorbent pads or surgical articles; materials for bandages, dressings, absorbent pads or surgical articlesA61L31/10PVGPATDIS, file of 2026-04-10
A61PSpecific therapeutic activity of chemical compounds or medicinal preparationsA61P1/00PVGPATDIS, file of 2026-04-10
C07KPeptidesC07K14/475PVGPATDIS, file of 2026-04-10

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

RecordedWhatFromToReel/frameSource
2024-01-30Government interest
Confirmatory license
UNIVERSITY OF ARKANSAS AT FAYETTEVILLE signed 2023-03-29NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT BETHESDA, MD66380/275ECORSEXC, file of 2026-09-25
2022-05-06Assignment
Assignment of assignor's interest
MATSUSHITA, OSAMU signed 2022-02-23NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY OKAYAMA59844/498ECORSEXC, file of 2026-09-25
2022-02-18Assignment
Assignment of assignor's interest
SAKON, JOSHUA signed 2021-02-26
ALJEWARI, HAZIM signed 2022-02-01
BEITLE, STEPHANIE signed 2022-02-04
BEITLE, ROBERT signed 2022-02-07
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS LITTLE ROCK, AR59052/428ECORSEXC, file of 2026-09-25

Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.