Patents

US 12403111 B2: Compositions and methods for treating neurodevelopmental disorders

Granted
2025-09-02
Filed
2025-01-31 application 19042105
Type
Utility · 20 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

Methods of treating neurodevelopmental disorders by administering an acetylated amino acid having a carbon-nitrogen bond and acetyl group covalently bound to the nitrogen of the carbon-nitrogen bond and having a three-dimensional structure that allows the acetylated amino acid to enter cells and neurons are described. In one embodiment, the acetylated amino acid is a compound of Formula (I): wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, and R14 is each independently H or D, or a pharmaceutically acceptable salt thereof. Pharmaceutical compositions containing the acetylated amino acid are also described.

Source: PVGPATDIS, file of 2026-04-10 (ipg250902.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
Syngap Research Fund 2 patentsUS company or organizationSan Diego, CASyngap Research Fund Inc State business registration FUZZY medium confidence: same name (legal endings aside) and state
SYNGAP RESEARCH FUND INCORPORATED Nonprofit FUZZY medium confidence: same name (governing-board words and legal endings aside) and state
PVGPATDIS, file of 2026-04-10
The University of Utah Research Foundation 932 patentsUS company or organizationSalt Lake City, UTUNIVERSITY OF UTAH RESEARCH FOUNDATION Nonprofit FUZZY medium confidence: same name (governing-board words and legal endings aside) and statePVGPATDIS, file of 2026-04-10

Inventors

InventorPlacePatentsPerson pageSource
Katherine BeebeSalt Lake City, UT1PVGPATDIS, file of 2026-04-10
Clement Y. ChowSalt Lake City, UT3PVGPATDIS, file of 2026-04-10
Mike GragliaMill Valley, CA2PVGPATDIS, file of 2026-04-10
Marta Caceres DahiyaArlington, TX2Person page FUZZY high confidencePVGPATDIS, file of 2026-04-10
Kathryn HeldeSeattle, WA2PVGPATDIS, file of 2026-04-10
Lindsay WieczorekChaska, MN2Person page FUZZY high confidencePVGPATDIS, file of 2026-04-10

CPC categories

SubclassCategoryFirst groupSource
A61KPreparations for medical, dental or toiletry purposesA61K31/197PVGPATDIS, file of 2026-04-10
A61PSpecific therapeutic activity of chemical compounds or medicinal preparationsA61P25/08PVGPATDIS, file of 2026-04-10

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

RecordedWhatFromToReel/frameSource
2025-02-13Assignment
Assignment of assignor's interest
UNIVERSITY OF UTAH signed 2025-02-12UNIVERSITY OF UTAH RESEARCH FOUNDATION SALT LAKE CITY, UT70205/547ECORSEXC, file of 2026-09-25
2025-01-31Assignment
Assignment of assignor's interest
BEEBE, KATHERINE signed 2025-01-28
CHOW, CLEMENT Y. signed 2025-01-28
UNIVERSITY OF UTAH SALT LAKE CITY, UT70073/363ECORSEXC, file of 2026-09-25
2025-01-31Assignment
Assignment of assignor's interest
DAHIYA, MARTA CACERES signed 2025-01-29
GRAGLIA, MIKE signed 2025-01-29
HELDE, KATHRYN signed 2025-01-29
WIECZOREK, LINDSAY signed 2025-01-29
SYNGAP RESEARCH FUND SAN DIEGO, CA70073/357ECORSEXC, file of 2026-09-25

Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.