Patents

US 12400737 B2: Methods of classifying diffuse large B-cell lymphoma

Granted
2025-08-26
Filed
2019-10-09 application 16597654
Type
Utility · 24 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

A method of predicting if a subject has an Activated B Cell-like (ABC) subtype or a non-ABC subtype of Diffuse Large B-Cell Lymphoma (DLBCL), comprising (a) obtaining a sample from the subject; (b) measuring the expression levels of CD10, MUM1, FOXP1, and optionally Bcl-6; (c) determining a composite score based on the expression levels of CD10, MUM1, and FOXP1, and optionally Bcl-6; and (d) predicting if the subject has an ABC subtype or a non-ABC subtype of DLBCL based on the composite score.

Source: PVGPATDIS, file of 2026-04-10 (ipg250826.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
Celgene Corporation 413 patentsUS company or organizationSummit, NJPVGPATDIS, file of 2026-04-10

Inventors

InventorPlacePatentsPerson pageSource
Yixin WangJalan Pedongkelan, NJ6PVGPATDIS, file of 2026-04-10
Sarah HerseyMendham, NJ1PVGPATDIS, file of 2026-04-10
Fadi George TowficMadison, NJ1PVGPATDIS, file of 2026-04-10
Alberto Risueno PerezSevilla, ES2PVGPATDIS, file of 2026-04-10

CPC categories

SubclassCategoryFirst groupSource
G01NInvestigating or analysing materials by determining their chemical or physical propertiesG01N33/57505PVGPATDIS, file of 2026-04-10
G16BBioinformatics, i.e. information and communication technology [ict] specially adapted for genetic or protein-related data processing in computational molecular biologyG16B20/30PVGPATDIS, file of 2026-04-10
G16HHealthcare informatics, i.e. information and communication technology [ict] specially adapted for the handling or processing of medical or healthcare dataG16H50/20PVGPATDIS, file of 2026-04-10

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

RecordedWhatFromToReel/frameSource
2020-10-23Assignment
Assignment of assignor's interest
CELGENE RESEARCH S.L.U. signed 2019-10-03CELGENE CORPORATION SUMMIT, NJ54150/334ECORSEXC, file of 2026-09-25
2020-10-23Assignment
Assignment of assignor's interest
RISUENO PEREZ, ALBERTO signed 2019-04-12CELGENE RESEARCH S.L.U. SEVILLA54150/314ECORSEXC, file of 2026-09-25
2020-10-23Assignment
Assignment of assignor's interest
WANG, YIXIN signed 2019-04-19
HERSEY, SARAH signed 2019-05-06
TOWFIC, FADI GEORGE signed 2019-10-08
CELGENE CORPORATION SUMMIT, NJ54150/227ECORSEXC, file of 2026-09-25

Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.