Patents
US 12392785 B2: Adjusted multi-biomarker disease activity score for inflammatory disease assessment
- Granted
- 2025-08-19
- Filed
- 2018-07-30 application 16635093
- Type
- Utility · 4 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Provided herein are methods for assessing response to inflammatory disease therapy. The methods include performing immunoassays to generate scores based on quantitative data for expression of biomarkers relating to inflammatory biomarkers to assess disease activity in inflammatory diseases, e.g., rheumatoid arthritis. Also provided are methods of adjusting disease activity scores to account for variables that can influence such scores.
Source: PVGPATDIS, file of 2026-04-10 (ipg250819.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Laboratory Corporation of America Holdings 128 patents | US company or organization | Burlington, NC | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Ching Chang Hwang | South San Francisco, CA | 1 | PVGPATDIS, file of 2026-04-10 | |
| David Chernoff | South San Francisco, CA | 8 | PVGPATDIS, file of 2026-04-10 | |
| Alexander Gutin | Salt Lake City, UT | 33 | PVGPATDIS, file of 2026-04-10 | |
| Darl Flake | Salt Lake City, UT | 6 | PVGPATDIS, file of 2026-04-10 | |
| Jerry Lanchbury | Salt Lake City, UT | 12 | PVGPATDIS, file of 2026-04-10 | |
| Paul Scott Eastman | South San Francisco, CA | 4 | PVGPATDIS, file of 2026-04-10 | |
| Eric Sasso | South San Francisco, CA | 7 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P29/00 | PVGPATDIS, file of 2026-04-10 |
| G01N | Investigating or analysing materials by determining their chemical or physical properties | G01N33/6893 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2021-10-06 | Assignment Assignment of assignor's interest | CRESCENDO BIOSCIENCE, INC. signed 2021-09-13 | LABORATORY CORPORATION OF AMERICA HOLDINGS BURLINGTON, NC | 57709/825 | PASDL, file of 2026-10-15 |
| 2021-08-02 | Assignment Assignment of assignor's interest | SASSO, ERIC signed 2021-07-12 CHERNOFF, DAVID signed 2021-07-26 EASTMAN, PAUL SCOTT signed 2021-07-26 GUTIN, ALEXANDER signed 2021-07-26 HWANG, CHING CHANG signed 2021-07-26 LANCHBURY, JERRY signed 2021-07-28 FLAKE, DARL signed 2021-07-29 | MYRIAD GENETICS, INC. SALT LAKE CITY, UT | 57057/253 | ECORSEXC, file of 2026-09-25 |
| 2021-05-14 | Assignment Assignment of assignor's interest | MYRIAD GENETICS, INC. signed 2021-04-28 | CRESCENDO BIOSCIENCE, INC. SOUTH SAN FRANCISCO, CA | 56246/689 | PASDL, file of 2026-10-15 |
| 2021-02-25 | Assignment Assignment of assignor's interest | CHERNOFF, DAVID signed 2021-02-17 SASSO, ERIC signed 2021-02-17 EASTMAN, PAUL SCOTT signed 2021-02-18 HWANG, CHING CHANG signed 2021-02-18 | CRESCENDO BIOSCIENCE SOUTH SAN FRANCISCO, CA | 55417/704 | ECORSEXC, file of 2026-09-25 |
| 2021-02-25 | Assignment Assignment of assignor's interest | FLAKE, DARL signed 2021-02-17 GUTIN, ALEXANDER signed 2021-02-17 LANCHBURY, JERRY signed 2021-02-19 | MYRIAD GENETICS, INC. SALT LAKE CITY, UT | 55417/620 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.