Patents
US 12371731 B2: Normalization of NGS library concentration
- Granted
- 2025-07-29
- Filed
- 2023-05-23 application 18322200
- Type
- Utility · 20 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
A bottleneck in the Next Generation Sequencing (NGS) workflow is the quantification of libraries for accurate pooling and loading of the sequencing instrument flow cell or chip. Disclosed herein are methods that improve performance and reduce time compared to existing methods.
Source: PVGPATDIS, file of 2026-04-10 (ipg250729.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| INTEGRATED DNA TECHNOLOGIES, INC. 103 patents | US company or organization | Coralville, IA | INTEGRATED DNA TECHNOLOGIES, INC. State business registration EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Vladimir Makarov | Ann Arbor, MI | 38 | PVGPATDIS, file of 2026-04-10 | |
| Sergey Chupreta | Gregory, MI | 4 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C12Q | Measuring or testing processes involving enzymes, nucleic acids or microorganisms ; compositions or test papers therefor; processes of preparing such compositions; condition-responsive control in microbiological or enzymological processes | C12Q1/6806 | PVGPATDIS, file of 2026-04-10 |
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N15/00 | PVGPATDIS, file of 2026-04-10 |
| C40B | Combinatorial chemistry; libraries, e.g. chemical libraries | C40B40/08 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2025-01-06 | Assignment Assignment of assignor's interest | CHUPRETA, SERGEY signed 2017-05-02 MAKAROV, VLADIMIR signed 2017-05-02 | SWIFT BIOSCIENCES, INC. ANN ARBOR, MI | 69823/480 | ECORSEXC, file of 2026-09-25 |
| 2025-01-06 | Merger Merger | SWIFT BIOSCIENCES, INC. signed 2022-03-18 | INTEGRATED DNA TECHNOLOGIES, INC. CORALVILLE, IA | 69750/323 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.