Patents

US 12366581 B2: Methods, compositions, and systems for detecting coronavirus neutralizing antibodies

Granted
2025-07-22
Filed
2021-06-25 application 17359064
Type
Utility · 17 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

The present disclosure relates to methods, compositions, and systems for detecting whether a subject exposed to a coronavirus has developed a neutralizing antibody response. Also disclosed are methods for determining whether a patient infected by a coronavirus is likely to respond to treatment with an antibody preparation. Also disclosed are methods for detecting the level of neutralizing antibody response in a sample of serum from a subject exposed to a coronavirus or to a coronavirus vaccine.

Source: PVGPATDIS, file of 2026-04-10 (ipg250722.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
Laboratory Corporation of America Holdings 128 patentsUS company or organizationBurlington, NCPVGPATDIS, file of 2026-04-10

Inventors

InventorPlacePatentsPerson pageSource
Christos J. PetropoulosRue de l'Église, CA8PVGPATDIS, file of 2026-04-10
Mary T. WrinFremont, CA4PVGPATDIS, file of 2026-04-10
Danielle DiTirroWalnut Creek, CA2PVGPATDIS, file of 2026-04-10

CPC categories

SubclassCategoryFirst groupSource
G01NInvestigating or analysing materials by determining their chemical or physical propertiesG01N33/6854PVGPATDIS, file of 2026-04-10
C07KPeptidesC07K14/005PVGPATDIS, file of 2026-04-10
C12NMicroorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture mediaC12N5/0686PVGPATDIS, file of 2026-04-10

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

RecordedWhatFromToReel/frameSource
2025-04-14Assignment
Assignment of assignor's interest
PETROPOULOS, CHRISTOS J. signed 2022-05-24
WRIN, MARY T. signed 2022-05-24
DITIRRO, DANIELLE signed 2022-04-15
LABORATORY CORPORATION OF AMERICA HOLDINGS BURLINGTON, NC70825/951PASDL, file of 2026-10-15

Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.