Patents

US 12364745 B2: Immunogenicity of a CpG-adjuvanted recombinant plague vaccine

Granted
2025-07-22
Filed
2023-06-29 application 18344780
Type
Utility · 15 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

The present disclosure relates to immunogenic compositions comprising at least one Yersinia pestis (Y. pestis) antigen, an aluminum salt adjuvant, and an oligonucleotide comprising an unmethylated cytidine-phospho-guanosine (CpG) motif. The immunogenic compositions are suitable for stimulating an immune response against Y. pestis in a subject in need thereof. The present disclosure also relates to kits and methods using the immunogenic compositions, or two separate compositions which together comprise the antigen, the aluminum salt adjuvant, and the oligonucleotide.

Source: PVGPATDIS, file of 2026-04-10 (ipg250722.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
DYNAVAX TECHNOLOGIES CORPORATION 50 patentsUS company or organizationEmeryville, CADYNAVAX TECHNOLOGIES CORP SEC filer FUZZY low confidence: same name (legal endings aside), one of each nationallyPVGPATDIS, file of 2026-04-10
THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE ARMY 183 patentsUS federal governmentNot reportedPVGPATDIS, file of 2026-04-10

Inventors

InventorPlacePatentsPerson pageSource
Robert JanssenPalm Springs, CA9PVGPATDIS, file of 2026-04-10
David NovackOakland, CA4PVGPATDIS, file of 2026-04-10
Wai Kwan ChungHagerstown, MD1PVGPATDIS, file of 2026-04-10
Andrew M. GlennGermantown, MD1PVGPATDIS, file of 2026-04-10
Lucy A. WardSilver Spring, MD5PVGPATDIS, file of 2026-04-10

CPC categories

SubclassCategoryFirst groupSource
A61KPreparations for medical, dental or toiletry purposesA61K39/0291PVGPATDIS, file of 2026-04-10
A61PSpecific therapeutic activity of chemical compounds or medicinal preparationsA61P31/04PVGPATDIS, file of 2026-04-10
Y02ATechnologies for adaptation to climate changeY02A50/30PVGPATDIS, file of 2026-04-10

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

RecordedWhatFromToReel/frameSource
2024-01-30Assignment
Assignment of assignor's interest
JANSSEN, ROBERT S. signed 2023-07-17
NOVACK, DAVID signed 2023-07-17
DYNAVAX TECHNOLOGIES CORPORATION EMERYVILLE, CA66300/720ECORSEXC, file of 2026-09-25
2023-07-11Assignment
Assignment of assignor's interest
GLENN, ANDREW signed 2023-07-05
WARD, LUCY signed 2023-07-05
CHUNG, WAI KWAN signed 2023-07-06
THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY FORT DETRICK, MD64208/356ECORSEXC, file of 2026-09-25

Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.