Patents
US 12337025 B2: Mutated e. coli enterotoxins as anti-inflammatory agents
- Granted
- 2025-06-24
- Filed
- 2019-05-07 application 17053635
- Type
- Utility · 19 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The invention provides compositions and methods for reducing symptoms of inflammation by administering therapeutically effective amounts of (a) (1) enterotoxic E. coli heat labile detoxified toxin A subunit that interferes with the function of ADP-ribosylation factor and inhibits ADP-ribosylation, or (2) A1 subunit that interferes with the function of ADP-ribosylation factor and inhibits ADP-ribosylation, or both (1) and (2), and (b) a carrier that causes internalization of the A subunit or A1 subunit, or both, into cells.
Source: PVGPATDIS, file of 2026-04-10 (ipg250624.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| The Administrators of the Tulane Educational Fund 124 patents | US company or organization | New Orleans, LA | The Administrators of the Tulane Educational Fund State business registration EXACT high confidence: identical full name and state Tulane University of Louisiana College or university EXACT high confidence: through the nonprofit with the college's EIN (identical full name and state) THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND Nonprofit EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Elizabeth B. Norton | New Orleans, LA | 2 | PVGPATDIS, file of 2026-04-10 | |
| John D. Clements | Dadeville, AL | 3 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K38/164 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P29/00 | PVGPATDIS, file of 2026-04-10 |
| C07K | Peptides | C07K14/245 | PVGPATDIS, file of 2026-04-10 |
| Y02A | Technologies for adaptation to climate change | Y02A50/30 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2025-05-14 | Assignment Assignment of assignor's interest | CLEMENTS, JOHN DAVID, DR. signed 2019-05-01 | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND NEW ORLEANS, LA | 71117/511 | ECORSEXC, file of 2026-09-25 |
| 2025-05-14 | Assignment Assignment of assignor's interest | NORTON, ELIZABETH BRAY, DR. signed 2019-05-02 | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND NEW ORLEANS, LA | 71117/478 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.