Patents
US 12324807 B2: Combination therapy for PI3K-associated disease or disorder
- Granted
- 2025-06-10
- Filed
- 2019-05-31 application 15733852
- Type
- Utility · 40 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Described herein are compositions and methods for treating a disease or disorder associated with PI3K signaling. For example, such compositions can include use of modulators of glucose metabolism, use of at least one kinase in the insulin-receptor/PI3K/AKT/mTOR pathway, and/or use of diet that influences the subject's metabolic state.
Source: PVGPATDIS, file of 2026-04-10 (ipg250610.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| CORNELL UNIVERSITY 1,393 patents | US company or organization | Ithaca, NY | CORNELL UNIVERSITY State business registration EXACT high confidence: identical full name and state Cornell University College or university EXACT high confidence: identical full name and state CORNELL UNIVERSITY Nonprofit EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
| COLUMBIA UNIVERSITY 26 patents | US company or organization | New York, NY | TRUSTEES OF COLUMBIA UNIVERSITY Nonprofit FUZZY medium confidence: same name (governing-board words and legal endings aside) and state | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Lewis C. Cantley | Cambridge, MA | 15 | PVGPATDIS, file of 2026-04-10 | |
| Benjamin Hopkins | Larchmont, NY | 1 | PVGPATDIS, file of 2026-04-10 | |
| Marcus Goncalves | Garden City, NY | 2 | PVGPATDIS, file of 2026-04-10 | |
| Siddhartha Mukherjee | New York, NY | 11 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A23L | Foods, foodstuffs or non-alcoholic beverages, not otherwise provided for; preparation or treatment thereof | A23L33/20 | PVGPATDIS, file of 2026-04-10 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K31/5377 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P3/10 | PVGPATDIS, file of 2026-04-10 |
| A23V | Indexing scheme relating to foods, foodstuffs or non-alcoholic beverages and lactic or propionic acid bacteria used in foodstuffs or food preparation | A23V2002/00 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2021-04-21 | Assignment Assignment of assignor's interest | CANTLEY, LEWIS C signed 2021-02-22 HOPKINS, BENJAMIN signed 2021-03-04 GONCALVES, MARCUS signed 2021-03-22 | CORNELL UNIVERSITY ITHACA, NY | 55988/564 | ECORSEXC, file of 2026-09-25 |
| 2021-04-21 | Assignment Assignment of assignor's interest | MUKHERJEE, SIDDHARTHA signed 2021-02-24 | COLUMBIA UNIVERSITY NEW YORK, NY | 55988/446 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.