Patents
US 12312376 B2: Therapeutic double stranded RNA and methods for producing the same
- Granted
- 2025-05-27
- Filed
- 2021-01-25 application 17773545
- Type
- Utility · 8 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Disclosed is a method for the synthesis of a therapeutic double-stranded RNA (tdsRNA), comprising: a) synthesizing a first single-stranded RNA (first ssRNA) in a first synthesis reaction with PNPase as the only RNA polymerase; b) synthesizing a second single-stranded RNA (second ssRNA) in a second synthesis reaction with PNPase as the only RNA polymerase; and c) hybridizing the first ssRNA with the second ssRNA to form the tdsRNA; wherein step a) and step b) are performed in any order. Also disclosed is a product produced by the method.
Source: PVGPATDIS, file of 2026-04-10 (ipg250527.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| AIM ImmunoTech Inc. 6 patents | US company or organization | Ocala, FL | AIM IMMUNOTECH INC. State business registration EXACT high confidence: identical full name and state AIM ImmunoTech Inc. Form D issuer EXACT high confidence: identical full name and state AIM IMMUNOTECH INC. SEC filer EXACT medium confidence: identical full name, one of each nationally | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Thomas K. EQUELS | Ocala, FL | 5 | Person page FUZZY medium confidence | PVGPATDIS, file of 2026-04-10 |
| Vishwajeetsinh M. Atodaria | Adams, NJ | 1 | PVGPATDIS, file of 2026-04-10 | |
| Victoria Scott | Langhorne, PA | 1 | PVGPATDIS, file of 2026-04-10 | |
| David Strayer | Bryn Mawr, PA | 11 | PVGPATDIS, file of 2026-04-10 | |
| Peter W. Rodino | Fort Myers, FL | 1 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07H | Sugars; derivatives thereof; nucleosides; nucleotides; nucleic acids | C07H21/02 | PVGPATDIS, file of 2026-04-10 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K31/713 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P31/14 | PVGPATDIS, file of 2026-04-10 |
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N15/10 | PVGPATDIS, file of 2026-04-10 |
| C12P | Fermentation or enzyme-using processes to synthesise a desired chemical compound or composition or to separate optical isomers from a racemic mixture | C12P19/34 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2022-04-29 | Assignment Assignment of assignor's interest | ATODARIA, VISHWAJEETSINH M. signed 2021-03-05 SCOTT, VICTORIA G. signed 2021-03-05 EQUELS, THOMAS K. signed 2021-03-08 RODINO, PETER W. signed 2021-03-08 STRAYER, DAVID R. signed 2021-03-23 | AIM IMMUNOTECH INC. OCALA, FL | 59717/262 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.