Patents
US 12286452 B2: Amphiphilic aminoglycoside connexin hemichannel inhibitors
- Granted
- 2025-04-29
- Filed
- 2020-12-11 application 17119301
- Type
- Utility · 5 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present invention includes novel molecules and methods of using an amphiphilic kanamycin molecule having substitutions at the O-4″, O-6″, or O-4″ and O-6″ positions having reduced antimicrobial activity for targeting Connexin Hemichannels.
Source: PVGPATDIS, file of 2026-04-10 (ipg250429.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Texas Tech University System 213 patents | US company or organization | Lubbock, TX | TEXAS TECH UNIVERSITY SYSTEM Federal lobbying client EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
| Utah State University 160 patents | US company or organization | Logan, UT | Utah State University College or university EXACT high confidence: identical full name and state UTAH STATE UNIVERSITY Nonprofit EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Guillermo A. Altenberg | Lubbock, TX | 4 | PVGPATDIS, file of 2026-04-10 | |
| Cheng-Wei Chang | Logan, UT | 75 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K31/7036 | PVGPATDIS, file of 2026-04-10 |
| C07H | Sugars; derivatives thereof; nucleosides; nucleotides; nucleic acids | C07H15/234 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P9/00 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2021-03-17 | Assignment Assignment of assignor's interest | CHANG, CHENG-WEI TOM signed 2018-12-11 | UTAH STATE UNIVERSITY LOGAN, UT | 55623/573 | ECORSEXC, file of 2026-09-25 |
| 2021-03-17 | Assignment Assignment of assignor's interest | ALTENBERG, GUILLERMO A. signed 2018-09-12 | TEXAS TECH UNIVERSITY SYSTEM LUBBOCK, TX | 55623/484 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.