Patents
US 12278098 B2: High resolution imaging apparatus and method
- Granted
- 2025-04-15
- Filed
- 2024-03-20 application 18610570
- Type
- Utility · 5 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present invention relates to the high resolution imaging of samples using imaging mass spectrometry (IMS) and to the imaging of biological samples by imaging mass cytometry (IMC™) in which labelling atoms are detected by IMS. LA-ICP-MS (a form of IMS in which the sample is ablated by a laser, the ablated material is then ionised in an inductively coupled plasma before the ions are detected by mass spectrometry) has been used for analysis of various substances, such as mineral analysis of geological samples, analysis of archaeological samples, and imaging of biological substances. However, traditional LA-ICP-MS systems and methods may not provide high resolution. Described herein are methods and systems for high resolution IMS and IMC.
Source: PVGPATDIS, file of 2026-04-10 (ipg250415.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Standard BioTools Canada Inc. 12 patents | Foreign company or organization | Markham, CA | PVGPATDIS, file of 2026-04-10 | |
| University of Ottawa 100 patents | Foreign company or organization | Ottawa, CA | University of Ottawa College or university EXACT medium confidence: identical full name, one of each nationally UNIVERSITY OF OTTAWA Nonprofit EXACT medium confidence: identical full name, one of each nationally | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Paul Corkum | Ottawa, CA | 8 | PVGPATDIS, file of 2026-04-10 | |
| Alexander V. Loboda | Thornhill, CA | 19 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| G02B | Optical elements, systems or apparatus | G02B21/0032 | PVGPATDIS, file of 2026-04-10 |
| H01J | Electric discharge tubes or discharge lamps | H01J49/0463 | PVGPATDIS, file of 2026-04-10 |
| G01N | Investigating or analysing materials by determining their chemical or physical properties | G01N33/6848 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2024-03-20 | Assignment Assignment of assignor's interest | LOBODA, ALEXANDER signed 2019-07-23 CORKUM, PAUL, DR. signed 2021-03-01 | STANDARD BIOTOOLS CANADA INC. MARKHAM UNIVERSITY OF OTTAWA OTTAWA | 66843/450 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.