Patents
US 12070453 B2: Treatment of Fabry disease in ERT-naïve and ERT-experienced patients
- Granted
- 2024-08-27
- Filed
- 2017-07-19 application 16318905
- Type
- Utility · 17 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Provided are dosing regimens for the treatment of Fabry disease in a patient. Certain methods relate to the treatment of ERT-experienced or ERT-nave Fabry patients. Certain methods comprise administering to the patient about 123 mg free base equivalent of migalastat for improving left ventricular mass and/or improving podocyte globotriaosylceramide.
Source: PVGPATDIS, file of 2026-04-10 (ipg240827.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Amicus Therapeutics, Inc. 158 patents | US company or organization | Philadelphia, PA | AMICUS THERAPEUTICS, INC. Form D issuer EXACT high confidence: identical full name and state AMICUS THERAPEUTICS, INC. SEC filer EXACT medium confidence: identical full name, one of each nationally | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Jeff Castelli | New Hope, PA | 59 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K31/445 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P3/00 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2026-04-27 | Release of security interest Release of security interest | WILMINGTON TRUST, NATIONAL ASSOCIATION signed 2026-04-27 | AMICUS THERAPEUTICS, INC. PHILADELPHIA, PA | 75494/30 | PASDL, file of 2026-08-13 |
| 2026-04-27 | Security interest Security interest Security interest | BIOMARIN PHARMACEUTICAL INC. signed 2026-04-27 AMICUS THERAPEUTICS, INC. signed 2026-04-27 | CITIBANK, N.A., AS COLLATERAL AGENT NEW YORK, NY | 75493/968 | PASDL, file of 2026-10-15 |
| 2024-07-11 | Assignment Assignment of assignor's interest | CASTELLI, JEFF signed 2024-07-11 | AMICUS THERAPEUTICS, INC. PHILADELPHIA, PA | 67959/418 | PASDL, file of 2026-10-15 |
| 2023-10-06 | Security interest Security interest Security interest | AMICUS THERAPEUTICS, INC. signed 2023-10-05 | WILMINGTON TRUST, NATIONAL ASSOCIATION MINNEAPOLIS, MN | 65177/196 | PASDL, file of 2026-10-15 |
| 2023-10-06 | Release of security interest Release of security interest | HAYFIN SERVICES LLP signed 2023-10-05 | AMICUS THERAPEUTICS, INC. PRINCETON, NJ | 65164/945 | PASDL, file of 2026-10-15 |
| 2020-07-30 | Security interest Security interest Security interest | AMICUS THERAPEUTICS, INC. signed 2020-07-30 | HAYFIN SERVICES LLP, AS AGENT LONDON | 53365/342 | PASDL, file of 2026-10-15 |
| 2020-07-30 | Release of security interest Release of security interest | BPCR LIMITED PARTNERSHIP signed 2020-07-30 | AMICUS THERAPEUTICS, INC. CRANBURY, NJ | 53360/659 | PASDL, file of 2026-10-15 |
| 2020-05-21 | Assignment Omnibus confirmation of assignment agreement | BIOPHARMA CREDIT PLC signed 2020-05-21 | BPCR LIMITED PARTNERSHIP EXETER EX4 4EP | 52741/173 | PASDL, file of 2026-10-15 |
| 2020-05-11 | Security interest Security interest Security interest | AMICUS THERAPEUTICS, INC. signed 2020-05-07 | BIOPHARMA CREDIT PLC EXETER EX4 4EP | 52625/916 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.