Patents
US 12054762 B2: Methods of protein production using anti-senescence compounds
- Granted
- 2024-08-06
- Filed
- 2008-04-22 application 12107533
- Type
- Utility · 30 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Methods of producing a protein in cell culture comprising an anti-senescence compound, such as the antioxidant carnosine, are provided. According to teachings of the present invention, cells grown in a cell culture medium comprising an anti-senescence compound exhibit increased viability and productivity. Furthermore, cell cultures grown in the presence of an anti-senescence compound exhibit decreased levels of high molecular weight aggregates in the cell culture medium.
Source: PVGPATDIS, file of 2026-04-10 (ipg240806.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Wyeth, LLC 476 patents | US company or organization | Madison, NJ | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Jose Manuel Gomes | Chelmsford, MA | 4 | PVGPATDIS, file of 2026-04-10 | |
| Yen-Tung Luan | Chelmsford, MA | 5 | PVGPATDIS, file of 2026-04-10 | |
| Gregory Walter HILLER | Wakefield, MA | 11 | PVGPATDIS, file of 2026-04-10 | |
| Wenge Wang | North Chelmsford, MA | 7 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C12P | Fermentation or enzyme-using processes to synthesise a desired chemical compound or composition or to separate optical isomers from a racemic mixture | C12P21/02 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P37/02 | PVGPATDIS, file of 2026-04-10 |
| C07K | Peptides | C07K14/70578 | PVGPATDIS, file of 2026-04-10 |
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N2500/33 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2010-06-16 | Name change Change of name | WYETH signed 2009-11-09 | WYETH LLC MADISON, NJ | 24541/922 | PASDL, file of 2026-10-15 |
| 2008-06-26 | Assignment Assignment of assignor's interest | GOMES, JOSE MANUEL signed 2008-06-13 HILLER, GREGORY W. signed 2008-06-13 WANG, WENGE signed 2008-06-13 LUAN, YEN-TUNG signed 2008-06-16 | WYETH MADISON, NJ | 21155/955 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.