Patents
US 11827641 B2: Toll-like receptor antagonist compounds and methods of use
- Granted
- 2023-11-28
- Filed
- 2022-05-20 application 17664305
- Type
- Utility · 25 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The invention relates to compounds of formula (I): or a salt or solvate thereof, wherein the variables are as described herein. Compounds of formula (I) and pharmaceutical compositions thereof are antagonists of toll-like receptors such as TLR7, TLR8 and/or TLR9 that are useful for inhibiting immune response and treating diseases associated with undesirable immune response.
Source: PVGPATDIS, file of 2026-04-10 (ipg231128.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| DYNAVAX TECHNOLOGIES CORPORATION 50 patents | US company or organization | Berkeley, CA | DYNAVAX TECHNOLOGIES CORP SEC filer FUZZY low confidence: same name (legal endings aside), one of each nationally | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Albert Frederick Candia, III | San Mateo, CA | 3 | PVGPATDIS, file of 2026-04-10 | |
| Richard Thomas Beresis | San Francisco, CA | 34 | PVGPATDIS, file of 2026-04-10 | |
| Robert L. Coffman | Portola Valley, CA | 23 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07D | Heterocyclic compounds | C07D487/04 | PVGPATDIS, file of 2026-04-10 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K45/06 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P35/00 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2022-05-26 | Assignment Assignment of assignor's interest | CANDIA, ALBERT FREDERICK, III signed 2019-05-13 BERESIS, RICHARD THOMAS signed 2019-05-15 COFFMAN, ROBERT L signed 2019-05-13 | DYNAVAX TECHNOLOGIES CORPORATION BERKELEY, CA | 60029/197 | PASDL, file of 2026-08-03 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.