Patents
US 11802283 B2: Oligonucleotide analogues targeting human LMNA
- Granted
- 2023-10-31
- Filed
- 2020-09-17 application 17024100
- Type
- Utility · 4 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Provided are LMNA-targeted antisense oligonucleotides for reducing expression of one or more aberrantly spliced LMNA mRNA isoforms that encode progerin.
Source: PVGPATDIS, file of 2026-04-10 (ipg231031.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| SAREPTA THERAPEUTICS, INC. 126 patents | US company or organization | Cambridge, MA | Sarepta Therapeutics, Inc. Form D issuer EXACT high confidence: identical full name and state SAREPTA THERAPEUTICS, INC. SEC filer EXACT medium confidence: identical full name, one of each nationally | PVGPATDIS, file of 2026-04-10 |
| The United States of America as Represented by the Secretary, Dept. of Health and Human Services 69 patents | US federal government | Bethesda, MD | PVGPATDIS, file of 2026-04-10 | |
| UNIVERSITY OF MARYLAND 180 patents | US company or organization | Not reported | UNIVERSITY OF MARYLAND Nonprofit EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
| The Progeria Research Foundation 10 patents | US company or organization | Peabody, MA | The Progeria Research Foundation, Inc. State business registration FUZZY medium confidence: same name (legal endings aside) and state THE PROGERIA RESEARCH FOUNDATION INC Nonprofit FUZZY medium confidence: same name (governing-board words and legal endings aside) and state | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Michael R. Erdos | Bethesda, MD | 5 | PVGPATDIS, file of 2026-04-10 | |
| Francis S. Collins | Bethesda, MD | 12 | PVGPATDIS, file of 2026-04-10 | |
| Kan Cao | Bowie, MD | 7 | PVGPATDIS, file of 2026-04-10 | |
| Ryszard Kole | Cambridge, MA | 24 | PVGPATDIS, file of 2026-04-10 | |
| Richard K. Bestwick | Cambridge, MA | 18 | PVGPATDIS, file of 2026-04-10 | |
| Leslie B. Gordon | Foxborough, MA | 13 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N15/113 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P43/00 | PVGPATDIS, file of 2026-04-10 |
| C07K | Peptides | C07K7/06 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2023-06-08 | Assignment Assignment of assignor's interest | GORDON, LESLIE B. signed 2019-01-30 | PROGERIA RESEARCH FOUNDATION, INC. PEABODY, MA | 63895/44 | ECORSEXC, file of 2026-09-25 |
| 2023-06-08 | Assignment Assignment of assignor's interest | ERDOS, MICHAEL R. signed 2019-01-10 | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES BETHESDA, MD | 63894/772 | ECORSEXC, file of 2026-09-25 |
| 2023-06-08 | Assignment Assignment of assignor's interest | BESTWICK, RICHARD KEITH signed 2019-01-07 KOLE, RYSZARD signed 2019-01-07 | SAREPTA THERAPEUTICS, INC. CAMBRIDGE, MA | 63894/680 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.