Patents

US 11771852 B2: Electronic breath actuated in-line droplet delivery device with small volume ampoule and methods of use

Granted
2023-10-03
Filed
2018-11-08 application 16762101
Type
Utility · 19 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

A droplet delivery device with a small volume drug ampoule and related methods for delivering precise and repeatable dosages to a subject for pulmonary use is disclosed. The droplet delivery device is configured to facilitate the ejection of small, e.g., single use, volumes of a therapeutic agent. The droplet delivery device includes a housing, a mouthpiece, a small volume drug ampoule, an ejector mechanism, and at least one differential pressure sensor. The delivery device is automatically breath actuated by the user when the differential pressure sensor senses a predetermined pressure change within housing. The droplet delivery device is then actuated to generate a plume of droplets having an average ejected particle diameter within the respirable size range, e.g, less than about 5-6 μm, so as to target the pulmonary system of the user. The small volume drug ampoule may include a reservoir which comprises an internal flexible membrane separating two internal volumes, a first background pressure fluid volume and a second drug volume.

Source: PVGPATDIS, file of 2026-04-10 (ipg231003.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
PNEUMA RESPIRATORY, INC. 28 patentsUS company or organizationBoone, NCPneuma Respiratory, Inc. Form D issuer EXACT high confidence: identical full name and statePVGPATDIS, file of 2026-04-10

Inventors

InventorPlacePatentsPerson pageSource
John H. HebrankDurham, NC51PVGPATDIS, file of 2026-04-10
Christopher W. MaurerIrvine, CA38PVGPATDIS, file of 2026-04-10
Charles Eric HunterBoone, NC53PVGPATDIS, file of 2026-04-10
Chengjie LiLo Wu, CN24PVGPATDIS, file of 2026-04-10
Louis Thomas GerminarioKingsport, TN27PVGPATDIS, file of 2026-04-10

CPC categories

SubclassCategoryFirst groupSource
A61MDevices for introducing media into, or onto, the body ; devices for transducing body media or for taking media from the body ; devices for producing or ending sleep or stuporA61M15/0085PVGPATDIS, file of 2026-04-10

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

No recorded assignments or security interests on file for this patent.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.