Patents
US 11746374 B2: Methods and platform for screening and selecting metabolites and their receptors
- Granted
- 2023-09-05
- Filed
- 2018-06-15 application 16622445
- Type
- Utility · 18 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Disclosed herein are methods and platforms using Receptor Compartmentalized Partnered Replication (CPR), in which the partner gene is a receptor, signal transduction pathway, or metabolic pathway that leads to the production of an effector molecule for the receptor or signal transduction pathway. The signal transduction pathway or receptor is coupled to the production of a thermostable polymerase. Emulsification of libraries of organisms with primers that can amplify the partner gene led to the selective amplification of those partner genes that were best able to produce the thermostable polymerase during thermal cycling of the emulsion.
Source: PVGPATDIS, file of 2026-04-10 (ipg230905.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 3,356 patents | US company or organization | Austin, TX | PVGPATDIS, file of 2026-04-10 | |
| Texas A&M University 14 patents | US company or organization | College Station, TX | TEXAS A & M UNIVERSITY Nonprofit EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Andrew Ellington | Austin, TX | 28 | PVGPATDIS, file of 2026-04-10 | |
| Jimmy Gollihar | Hewitt, TX | 7 | PVGPATDIS, file of 2026-04-10 | |
| Katy KAO | College Station, TX | 1 | PVGPATDIS, file of 2026-04-10 | |
| Elizabeth GARDNER | Austin, TX | 1 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C12Q | Measuring or testing processes involving enzymes, nucleic acids or microorganisms ; compositions or test papers therefor; processes of preparing such compositions; condition-responsive control in microbiological or enzymological processes | C12Q1/6811 | PVGPATDIS, file of 2026-04-10 |
| C07K | Peptides | C07K14/705 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2020-01-09 | Assignment Assignment of assignor's interest | KAO, KATY signed 2018-06-25 | THE TEXAS A&M UNIVERSITY SYSTEM COLLEGE STATION, TX | 51464/647 | PASDL, file of 2026-10-15 |
| 2020-01-09 | Assignment Assignment of assignor's interest | ELLINGTON, ANDREW signed 2019-12-11 GOLLIHAR, JIMMY signed 2018-08-15 GARDNER, ELIZABETH signed 2019-12-11 | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM AUSTIN, TX | 51464/599 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.