Patents
US 11613547 B2: G-protein biased opioid receptor agonist/analgesics with reduced arrestin recruitment
- Granted
- 2023-03-28
- Filed
- 2020-07-08 application 16924037
- Type
- Utility · 19 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
In some aspects, the present disclosure provides compounds of the formula: wherein the variables are as defined herein. In some embodiments, these compounds may be used to reduce the pain of a patient. These compounds may be used in pain relief and show an improved pharmaceutical profile relative to other commonly used opiates and opioid derivatives.
Source: PVGPATDIS, file of 2026-04-10 (ipg230328.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| University of Health Sciences and Pharmacy in St. Louis 2 patents | US company or organization | Chesterfield, MO | University of Health Sciences and Pharmacy in St. Louis College or university EXACT high confidence: identical full name and state UNIVERSITY OF HEALTH SCIENCES AND PHARMACY IN ST LOUIS Nonprofit EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
| University of Southern California 1,067 patents | US company or organization | Los Angeles, CA | University of Southern California College or university EXACT high confidence: identical full name and state UNIVERSITY OF SOUTHERN CALIFORNIA, INC. State business registration FUZZY medium confidence: same name (legal endings aside) and state | PVGPATDIS, file of 2026-04-10 |
| THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 761 patents | US company or organization | Chapel Hill, NC | The University of North Carolina at Chapel Hill State business registration EXACT high confidence: identical full name and state University of North Carolina at Chapel Hill College or university FUZZY medium confidence: same name (governing-board words and legal endings aside) and state UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL Nonprofit FUZZY medium confidence: same name (governing-board words and legal endings aside) and state | PVGPATDIS, file of 2026-04-10 |
| Memorial Sloan Kettering Cancer Center 560 patents | US company or organization | New York, NY | PVGPATDIS, file of 2026-04-10 | |
| University of Florida Research Foundation, Inc. 1,814 patents | US company or organization | Gainesville, FL | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION INC State business registration EXACT high confidence: identical full name and state UNIVERSITY OF FLORIDA RESEARCH FOUNDATION INC Nonprofit EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Susruta Majumdar | Chesterfield, MO | 7 | PVGPATDIS, file of 2026-04-10 | |
| Vsevolod Katritch | Los Angeles, CA | 2 | PVGPATDIS, file of 2026-04-10 | |
| Bryan Roth | Chapel Hill, NC | 10 | PVGPATDIS, file of 2026-04-10 | |
| Jay McLaughlin | Gainesville, FL | 6 | PVGPATDIS, file of 2026-04-10 | |
| Saheem ZAIDI | Los Angeles, CA | 2 | PVGPATDIS, file of 2026-04-10 | |
| Gavril Pasternak | Not reported | 6 | PVGPATDIS, file of 2026-04-10 | |
| Rajendra Uprety | Cary, NC | 3 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07D | Heterocyclic compounds | C07D489/00 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P25/04 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2026-02-25 | Other License | ST. LOUIS COLLEGE OF PHARMACY signed 2023-02-27 | NATIONAL INSTITUTES OF HEALTH BETHESDA, MD | 74976/670 | PASDL, file of 2026-10-15 |
| 2021-07-25 | Assignment Assignment of assignor's interest | MAJUMDAR, SUSRUTA signed 2020-03-09 | UNIVERSITY OF HEALTH SCIENCES & PHARMACY IN ST. LOUIS ST. LOUIS, MO | 56971/811 | ECORSEXC, file of 2026-09-25 |
| 2021-07-25 | Assignment Assignment of assignor's interest | MCLAUGHLIN, JAY signed 2020-08-20 | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED GAINESVILLE, FL | 56971/806 | ECORSEXC, file of 2026-09-25 |
| 2021-07-25 | Assignment Assignment of assignor's interest | PASTERNAK, ANNA R. signed 2020-02-20 UPRETY, RAJENDRA signed 2020-02-24 | MEMORIAL SLOAN KETTERING CANCER CENTER NEW YORK, NY | 56971/797 | ECORSEXC, file of 2026-09-25 |
| 2021-07-25 | Assignment Assignment of assignor's interest | ROTH, BRYAN signed 2020-11-11 | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL CHAPEL HILL, NC | 56971/792 | ECORSEXC, file of 2026-09-25 |
| 2021-07-25 | Assignment Assignment of assignor's interest | KATRITCH, VSEVOLOD signed 2021-03-23 ZAIDI, SAHEEM signed 2021-04-14 | UNIVERSITY OF SOUTHERN CALIFORNIA LOS ANGELES, CA | 56971/786 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.