Patents
US 11505537 B2: Compositions comprising methylphenidate-prodrugs, processes of making and using the same
- Granted
- 2022-11-22
- Filed
- 2020-12-08 application 17115425
- Type
- Utility · 12 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present technology is directed to compositions comprising d-threo-methylphenidate conjugates and/or unconjugated methylphenidate. The present technology also relates to compositions and oral formulations comprising d-threo-methylphenidate conjugated to nicotinoyl-L-serine, and/or a pharmaceutically acceptable salt thereof, and unconjugated methylphenidate and/or a pharmaceutically acceptable salt thereof. The present technology additionally relates to a pharmaceutical kit containing the composition comprising d-threo-methylphenidate conjugated to nicotinoyl-L-serine, and/or a pharmaceutically acceptable salt thereof, and unconjugated methylphenidate and/or a pharmaceutically acceptable salt thereof.
Source: PVGPATDIS, file of 2026-04-10 (ipg221122.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| KEMPHARM, INC. 57 patents | US company or organization | Intercession City, FL | KEMPHARM, INC Form D issuer EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Travis Mickle | Kissimmee, FL | 83 | PVGPATDIS, file of 2026-04-10 | |
| Sven Guenther | Coralville, IA | 63 | PVGPATDIS, file of 2026-04-10 | |
| Guochen Chi | Coralville, IA | 41 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07D | Heterocyclic compounds | C07D401/12 | PVGPATDIS, file of 2026-04-10 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K9/0053 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P3/04 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2026-09-11 | Security interest Security interest Security interest | COMMAVE THERAPEUTICS SA signed 2026-09-10 | TRUIST BANK, AS ADMINISTRATIVE AGENT ATLANTA, GA | 75980/787 | PASDL, file of 2026-09-15 |
| 2026-03-26 | Assignment Assignment of assignor's interest | ZEVRA THERAPEUTICS, INC. signed 2026-03-13 | COMMAVE THERAPEUTICS SA GENÈVE | 74195/8 | ECORSEXC, file of 2026-09-25 |
| 2026-03-25 | Name change Change of name | KEMPHARM, INC. signed 2023-02-21 | ZEVRA THERAPEUTICS, INC. CELEBRATION, FL | 75243/8 | PASDL, file of 2026-10-15 |
| 2026-03-25 | Assignment Assignment of assignor's interest | ZEVRA THERAPEUTICS, INC. signed 2026-03-13 | COMMAVE THERAPEUTICS SA GENEVA | 74186/531 | PASDL, file of 2026-10-15 |
| 2026-03-13 | Release of security interest Release of security interest | ALTER DOMUS (US) LLC signed 2026-03-12 | ZEVRA THERAPEUTICS, INC. CELEBRATION, FL | 75080/907 | PASDL, file of 2026-10-15 |
| 2024-04-08 | Security interest Security interest Security interest | ZEVRA THERAPEUTICS, INC. signed 2024-04-05 | ALTER DOMUS (US) LLC CHICAGO, IL | 67040/637 | PASDL, file of 2026-10-15 |
| 2021-01-14 | Assignment Assignment of assignor's interest | CHI, GUOCHEN signed 2019-11-07 GUENTHER, SVEN signed 2019-11-07 MICKLE, TRAVIS signed 2019-11-11 | KEMPHARM, INC. CELEBRATION, FL | 54920/66 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.