Patents
US 11458104 B1: Enteric coated tiopronin tablet
- Granted
- 2022-10-04
- Filed
- 2019-09-05 application 16562224
- Type
- Utility · 6 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
A solid pharmaceutical composition is provided that includes a core, an inner coating, and an outer coating. The core includes tiopronin as an active agent. Further, the inner coating, which includes a cellulose-based polymer, surrounds the core, and the outer coating, which includes an enteric polymer, surrounds the inner coating. As a result of the specific components of the solid pharmaceutical composition, the solid pharmaceutical composition exhibits a fed state Cmax of tiopronin that is at least 70% of a 12-hour fasted state Cmax of tiopronin after oral administration of the solid pharmaceutical composition when administered as a 300 milligram dose. As such, it is possible for the solid pharmaceutical composition to be administered orally with or without food (e.g., in a fed or fasted state) while still achieving a desired maximum plasma concentration of the tiopronin in a delayed release formulation.
Source: PVGPATDIS, file of 2026-04-10 (ipg221004.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| MISSION PHARMACAL COMPANY 8 patents | US company or organization | San Antonio, TX | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Jon Taylor | San Antonio, TX | 1 | PVGPATDIS, file of 2026-04-10 | |
| Stuart Smoot | San Antonio, TX | 1 | PVGPATDIS, file of 2026-04-10 | |
| Stuart Schoenherr | Spring Branch, TX | 5 | PVGPATDIS, file of 2026-04-10 | |
| Paul Werchan | Bulverde, TX | 1 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K9/2866 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2021-06-21 | Assignment Assignment of assignor's interest | SMOOT, STUART signed 2018-06-20 SCHOENHERR, STUART signed 2018-06-21 TAYLOR, JON signed 2018-06-21 WERCHAN, PAUL signed 2018-06-21 | MISSION PHARMACAL COMPANY SAN ANTONIO, TX | 56599/716 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.