Patents
US 11396653 B2: System for the biocontrol of disease-transmitting mosquitoes and their eggs using horizontally transferable symbiotic bacteria to deliver pathogen specific interfering RNA polynucleotides
- Granted
- 2022-07-26
- Filed
- 2018-07-10 application 16031607
- Type
- Utility · 14 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The inventive technology relates to novel paratransgenic strategies for the control of pathogens. The inventive technology may specifically include a novel paratransgenic system configured to deliver one or more inhibitory RNA molecules to pathogen/disease-transmitting organisms. In a preferred embodiment, the invention may include one or more genetically engineered symbiotic bacteria configured to persist throughout the life-cycle of a mosquito and deliver one or more interfering RNA molecules to pathogen/disease-transmitting mosquitoes.
Source: PVGPATDIS, file of 2026-04-10 (ipg220726.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Pebble Labs Inc. 7 patents | US company or organization | Los Alamos, NM | Pebble Labs Inc. Form D issuer EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
| Colorado State University Research Foundation 358 patents | US company or organization | Fort Collins, CO | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION Nonprofit EXACT high confidence: identical full name and state Colorado State University Research Foundation DBA CSU Strata State business registration FUZZY medium confidence: same name (legal endings aside) and state | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Richard T. Sayre | Los Alamos, NM | 29 | PVGPATDIS, file of 2026-04-10 | |
| Jiannong Xu | Las Cruces, NM | 8 | PVGPATDIS, file of 2026-04-10 | |
| Bradley R. Borlee | Fort Collins, CO | 2 | PVGPATDIS, file of 2026-04-10 | |
| Konstantinos Lymperopoulos | Los Alamos, NM | 1 | PVGPATDIS, file of 2026-04-10 | |
| Rebekah Kading | Fort Collins, CO | 1 | PVGPATDIS, file of 2026-04-10 | |
| William A. Black | Fort Collins, CO | 5 | PVGPATDIS, file of 2026-04-10 | |
| Kenneth C. Olson | Fort Collins, CO | 4 | PVGPATDIS, file of 2026-04-10 | |
| Carol Blair | Fort Collins, CO | 1 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N15/1131 | PVGPATDIS, file of 2026-04-10 |
| A01N | Preservation of bodies of humans or animals or plants or parts thereof ; biocides, e.g. as disinfectants, as pesticides or as herbicides ; pest repellants or attractants; plant growth regulators | A01N25/006 | PVGPATDIS, file of 2026-04-10 |
| Y02A | Technologies for adaptation to climate change | Y02A50/30 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2022-04-08 | Assignment Assignment of assignor's interest | BLAIR, CAROL signed 2022-01-06 KADING, REBEKAH signed 2022-01-06 BLACK, WILLIAM signed 2022-01-12 OLSON, KENNETH signed 2022-02-11 | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION FORT COLLINS, CO | 59546/244 | ECORSEXC, file of 2026-09-25 |
| 2021-12-07 | Assignment Assignment of assignor's interest | PEBBLE LABS USA INC. signed 2020-12-29 | PEBBLE LABS INC. LOS ALAMOS, NM | 58327/193 | ECORSEXC, file of 2026-09-25 |
| 2021-08-13 | Release of security interest Release of security interest | PEBBLE LABS INC. signed 2021-07-26 | GOTHAM GREEN FUND 1, L.P., GOTHAM GREEN FUND 1 (Q), L.P., GOTHAM GREEN FUND II, L.P., GOTHAM GREEN FUND II (Q), L.P., AND GOTHAM GREEN ADMIN 1, LLC SANTA MONICA, CA | 57176/338 | PASDL, file of 2026-10-15 |
| 2020-05-13 | Assignment Assignment of assignor's interest | SAYRE, RICHARD signed 2019-09-23 XU, JIANNONG signed 2019-09-23 LYMPEROPOULOS, KONSTANTINOS signed 2019-10-03 | PEBBLE LABS USA, INC. LOS ALAMOS, NM | 52652/642 | ECORSEXC, file of 2026-09-25 |
| 2018-10-23 | Assignment Assignment of assignor's interest | BORLEE, BRADLEY R. signed 2018-07-24 | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION FORT COLLINS, CO | 47272/75 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.