Patents
US 11299738 B2: Further novel oligonucleotide-ligand conjugates
- Granted
- 2022-04-12
- Filed
- 2018-04-05 application 16603211
- Type
- Utility · 23 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present invention relates to a compound comprising a modified saccharide moiety conjugated to a nucleic acid. The compound is useful in medicine for RNA interference therapy or for research and diagnostic purposes. In particular, the compound is useful in treating liver disease.
Source: PVGPATDIS, file of 2026-04-10 (ipg220412.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Sapience Therapeutics, Inc. 48 patents | US company or organization | Berlin, DE | SAPIENCE THERAPEUTICS, INC. State business registration EXACT high confidence: identical full name and state Sapience Therapeutics, Inc. Form D issuer EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Dmitry Samarsky | Berlin, DE | 30 | PVGPATDIS, file of 2026-04-10 | |
| Christian Frauendorf | Berlin, DE | 12 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07H | Sugars; derivatives thereof; nucleosides; nucleotides; nucleic acids | C07H21/00 | PVGPATDIS, file of 2026-04-10 |
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N15/1138 | PVGPATDIS, file of 2026-04-10 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K47/549 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P1/16 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2021-11-08 | Assignment Assignment of assignor's interest | SAMARSKY, DMITRY signed 2021-09-27 FRAUENDORF, CHRISTIAN signed 2021-10-12 | SILENCE THERAPEUTICS GMBH BERLIN | 58050/404 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.