Patents
US 11154559 B2: Methods and compositions of bile acids
- Granted
- 2021-10-26
- Filed
- 2012-09-28 application 13631095
- Type
- Utility · 19 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Methods and compositions are provided for treating metabolic disorders by modulating bile acid levels. Generally, the methods and compositions can modulate bile acid levels, such as serum bile acid levels, to treat a metabolic disorder. In one embodiment, a method of modulating a bile acid level includes measuring a bile acid level and delivering a composition effective to modulate the bile acid level. A method for modulating a bile acid profile includes comparing a bile acid profile to a target profile and delivering a bile acid cocktail to increase bile acid levels. In another embodiment, a pharmaceutical composition for increasing bile acid levels includes a bile acid cocktail effective to increase bile acid levels. The composition is further useful as part of an implantable system.
Source: PVGPATDIS, file of 2026-04-10 (ipg211026.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Ethicon Endo-Surgery, Inc. 1,347 patents | US company or organization | Cincinnati, OH | ETHICON ENDO-SURGERY. INC. State business registration EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
| The General Hospital Corporation 1,995 patents | US company or organization | Boston, MA | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Lee M. Kaplan | Wellesley, MA | 19 | PVGPATDIS, file of 2026-04-10 | |
| Nadia N. Ahmad | Medford, MA | 1 | PVGPATDIS, file of 2026-04-10 | |
| Jason L. Harris | Mason, OH | 1286 | PVGPATDIS, file of 2026-04-10 | |
| Kevin D. Felder | Cincinnati, OH | 55 | PVGPATDIS, file of 2026-04-10 | |
| Alessandro Pastorelli | Roma, IT | 18 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K31/56 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P1/00 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2013-01-23 | Assignment Assignment of assignor's interest | AHMAD, NADIA N. signed 2013-01-22 KAPLAN, LEE M. signed 2013-01-22 | THE GENERAL HOSPITAL CORPORATION D/B/A MASSACHUSETTS GENERAL HOSPITAL BOSTON, MA | 29680/353 | ECORSEXC, file of 2026-09-25 |
| 2013-01-23 | Assignment Assignment of assignor's interest | HARRIS, JASON L. signed 2012-10-11 FELDER, KEVIN D. signed 2012-10-16 PASTORELLI, ALESSANDRO signed 2012-11-13 | ETHICON ENDO-SURGERY, INC. CINCINNATI, OH | 29680/318 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.