Patents
US 11034697 B2: Process for the preparation of Remimazolam and solid state forms of Remimazolam salts
- Granted
- 2021-06-15
- Filed
- 2018-02-08 application 16484165
- Type
- Utility · 20 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present disclosure relates to novel processes for the preparation of short acting benzodiazepines as well as to novel intermediates in this process. More particularly the disclosure relates to processes and intermediates for preparation of Methyl 3-[(4S)-8-bromo-1-methyl-6-(pyridin-2-yl)-4H-imidazo[1,2-a][1,4]benzodiazepin-4-yl]propanoate, commonly known as Remimazolam. The present disclosure also relates to solid state forms of Remimazolam salts, processes for the preparation thereof, pharmaceutical formulations/compositions thereof, and methods of use thereof.
Source: PVGPATDIS, file of 2026-04-10 (ipg210615.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| WATSON LABORATORIES INC. 21 patents | US company or organization | Corona, CA | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Dolitzky Ben-Zion | Netanya, IL | 2 | PVGPATDIS, file of 2026-04-10 | |
| Mendelovici Marioara | Rehovot, IL | 2 | PVGPATDIS, file of 2026-04-10 | |
| Bodkhe Arjun Rajaram | Thane, IN | 2 | PVGPATDIS, file of 2026-04-10 | |
| Mane Ganesh Shivaji | Thane, IN | 2 | PVGPATDIS, file of 2026-04-10 | |
| Samala Rajamouli Srihari | Thane, IN | 2 | PVGPATDIS, file of 2026-04-10 | |
| Joshi Ashutosh Vijay | Thane, IN | 3 | PVGPATDIS, file of 2026-04-10 | |
| Parven Kumar Luthra | New Delhi, IN | 15 | PVGPATDIS, file of 2026-04-10 | |
| Amit Singh | Greater Noida, IN | 10 | PVGPATDIS, file of 2026-04-10 | |
| Anantha Rajmohan Muthusamy | Delhi, IN | 21 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07D | Heterocyclic compounds | C07D487/04 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P23/00 | PVGPATDIS, file of 2026-04-10 |
| C07B | General methods of organic chemistry; apparatus therefor | C07B2200/13 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2022-02-09 | Assignment Assignment of assignor's interest | WATSON LABORATORIES INC. signed 2022-02-08 | ASSIA CHEMICAL INDUSTRIES LTD. PETACH TIKVA | 58935/310 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.