Patents
US 11008373 B2: Designer osteogenic proteins
- Granted
- 2021-05-18
- Filed
- 2018-12-06 application 16211493
- Type
- Utility · 8 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.
Source: PVGPATDIS, file of 2026-04-10 (ipg210518.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Wyeth, LLC 476 patents | US company or organization | Madison, NJ | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Stephen Berasi | Arlington, MA | 8 | PVGPATDIS, file of 2026-04-10 | |
| Robert Vincent Martinez | Carlisle, MA | 5 | PVGPATDIS, file of 2026-04-10 | |
| Michael John Cain | Exeter, NH | 4 | PVGPATDIS, file of 2026-04-10 | |
| John M. Wozney | Hudson, MA | 12 | PVGPATDIS, file of 2026-04-10 | |
| Howard Seeherman | Cambridge, MA | 18 | PVGPATDIS, file of 2026-04-10 | |
| Zong Sean Juo | Cambridge, MA | 12 | PVGPATDIS, file of 2026-04-10 | |
| Valerie Calabro | Albi, FR | 10 | PVGPATDIS, file of 2026-04-10 | |
| Christopher BROWN | Chelmsford, MA | 19 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07K | Peptides | C07K14/51 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P11/00 | PVGPATDIS, file of 2026-04-10 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K38/16 | PVGPATDIS, file of 2026-04-10 |
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N5/10 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2019-03-22 | Assignment Assignment of assignor's interest | CAIN, MICHAEL JOHN signed 2011-07-27 CALABRO, VALERIE signed 2011-09-26 JUO, Z. SEAN signed 2011-09-26 SEEHERMAN, HOWARD signed 2011-09-26 BERASI, STEPHEN signed 2011-09-27 BROWN, CHRISTOPHER TODD signed 2011-09-27 WOZNEY, JOHN signed 2011-09-28 MARTINEZ, ROBERT VINCENT signed 2011-10-10 | WYETH LLC MADISON, NJ | 48667/309 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.