Patents
US 10969364 B1: Innovative nanopore sequencing technology including a self-assembled porous membrane
- Granted
- 2021-04-06
- Filed
- 2018-02-14 application 15896843
- Type
- Utility · 23 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Methods and apparatus for long read, label-free, optical nanopore long chain molecule sequencing. In general, the present disclosure describes a novel sequencing technology based on the integration of nanochannels to deliver single long-chain molecules with widely spaced (>wavelength), ˜1-nm aperture “tortuous” nanopores that slow translocation sufficiently to provide massively parallel, single base resolution using optical techniques. A novel, directed self-assembly nanofabrication scheme using simple colloidal nanoparticles is used to form the nanopore arrays atop nanochannels that unfold the long chain molecules. At the surface of the nanoparticle array, strongly localized electromagnetic fields in engineered plasmonic/polaritonic structures allow for single base resolution using optical techniques.
Source: PVGPATDIS, file of 2026-04-10 (ipg210406.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| STC.UNM 475 patents | US company or organization | Albuquerque, NM | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Steven R. J. Brueck | Albuquerque, NM | 80 | PVGPATDIS, file of 2026-04-10 | |
| Jeremy Scott Edwards | Albuquerque, NM | 16 | PVGPATDIS, file of 2026-04-10 | |
| Alexander Neumann | Albuquerque, NM | 39 | PVGPATDIS, file of 2026-04-10 | |
| Yuliya Kuznetsova | Albuquerque, NM | 14 | PVGPATDIS, file of 2026-04-10 | |
| Edgar A. Mendoza | Redondo Beach, CA | 6 | PVGPATDIS, file of 2026-04-10 | |
| C. Jeffrey Brinker | Albuquerque, NM | 27 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| G01N | Investigating or analysing materials by determining their chemical or physical properties | G01N27/44791 | PVGPATDIS, file of 2026-04-10 |
| B01L | Chemical or physical laboratory apparatus for general use | B01L3/502707 | PVGPATDIS, file of 2026-04-10 |
| C12Q | Measuring or testing processes involving enzymes, nucleic acids or microorganisms ; compositions or test papers therefor; processes of preparing such compositions; condition-responsive control in microbiological or enzymological processes | C12Q1/6869 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2018-10-22 | Assignment Assignment of assignor's interest | THE REGENTS OF THE UNIVERSITY OF NEW MEXICO signed 2018-10-03 | STC.UNM ALBUQUERQUE, NM | 47256/680 | ECORSEXC, file of 2026-09-25 |
| 2018-10-22 | Assignment Assignment of assignor's interest | BRINKER, CHARLES JEFFREY signed 2018-04-04 BRUECK, STEVEN signed 2018-08-24 EDWARDS, JEREMY signed 2018-09-11 KUZNETSOVA, YULIYA signed 2018-09-28 NEUMANN, ALEXANDER signed 2018-09-28 | THE REGENTS OF THE UNIVERSITY OF NEW MEXICO ALBUQUERQUE, NM | 47256/618 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.