Patents
US 10954212 B2: Compositions comprising methylphenidate-prodrugs, processes of making and using the same
- Granted
- 2021-03-23
- Filed
- 2019-09-30 application 16588914
- Type
- Utility · 7 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present technology is directed to d-threo-methylphenidate conjugates and a composition comprising d-threomethylphenidate conjugated to nicotinoyl-L-serine, or salt thereof. The present technology also relates to a composition comprising at least one conjugate of d-methylphenidate having at least two or more chiral centers. The composition is optically active. The present technology additionally relates to oral formulations and pharmaceutical kits comprising at least one d-threo-methylphenidate conjugate.The pharmaceutical kit may comprise a specified amount of individual doses in a package. Each individual dose in the package may contain a pharmaceutically effective amount of a conjugate of d-threo methylphenidate.
Source: PVGPATDIS, file of 2026-04-10 (ipg210323.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| KEMPHARM, INC. 57 patents | US company or organization | Four Corners, FL | KEMPHARM, INC Form D issuer EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Travis Mickle | Kissimmee, FL | 83 | PVGPATDIS, file of 2026-04-10 | |
| Sven Guenther | Coralville, IA | 63 | PVGPATDIS, file of 2026-04-10 | |
| Guochen Chi | Coralville, IA | 41 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07D | Heterocyclic compounds | C07D401/12 | PVGPATDIS, file of 2026-04-10 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K9/0053 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P3/04 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2026-09-11 | Security interest Security interest Security interest | COMMAVE THERAPEUTICS SA signed 2026-09-10 | TRUIST BANK, AS ADMINISTRATIVE AGENT ATLANTA, GA | 75980/787 | PASDL, file of 2026-09-15 |
| 2026-03-26 | Assignment Assignment of assignor's interest | ZEVRA THERAPEUTICS, INC. signed 2026-03-13 | COMMAVE THERAPEUTICS SA GENÈVE | 74195/8 | ECORSEXC, file of 2026-09-25 |
| 2026-03-25 | Assignment Assignment of assignor's interest | ZEVRA THERAPEUTICS, INC. signed 2026-03-13 | COMMAVE THERAPEUTICS SA GENEVA | 74186/531 | PASDL, file of 2026-10-15 |
| 2026-03-13 | Release of security interest Release of security interest | ALTER DOMUS (US) LLC signed 2026-03-12 | ZEVRA THERAPEUTICS, INC. CELEBRATION, FL | 75080/907 | PASDL, file of 2026-10-15 |
| 2024-04-08 | Security interest Security interest Security interest | ZEVRA THERAPEUTICS, INC. signed 2024-04-05 | ALTER DOMUS (US) LLC CHICAGO, IL | 67040/637 | PASDL, file of 2026-10-15 |
| 2024-02-26 | Name change Change of name | KEMPHARM, INC. signed 2023-02-21 | ZEVRA THERAPEUTICS, INC. CELEBRATION, FL | 66679/668 | PASDL, file of 2026-10-15 |
| 2019-12-11 | Assignment Assignment of assignor's interest | CHI, GUOCHEN signed 2019-11-07 GUENTHER, SVEN signed 2019-11-07 MICKLE, TRAVIS signed 2019-11-11 | KEMPHARM, INC. CELEBRATION, FL | 51245/645 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.