Patents

US 10729732 B2: Compositions of microbiota and methods related thereto

Granted: 2020-08-04
Filed: 2019-10-30 application 16669143
Type: Utility · 20 claims
Elsewhere: Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

Methods and compositions are provided for treating weight related conditions and metabolic disorders by altering microbiota in a subject. One aspect provides methods and compositions to alter microbiota in a subject by administering to the subject a composition that includes a substantially purified microbiota from phyla such as Bacteroidetes, Proteobacteria, Firmicutes and Verrucomicrobia or orders such as Bacteroidales, Verrucomicrobiales, Clostridiales and Enterobacteriales or genera such as Alistipes, Clostridium, Escherichia, and Akkermansia. Another aspect includes a pharmaceutical composition for altering microbiota that includes a therapeutically effective amount of substantially purified microbiota and a pharmaceutically acceptable carrier. Yet another aspect includes methods for treating a disorder, such as obesity, in a subject in need of such treatment by changing relative abundance of microbiota in a gastrointestinal tract of the subject without or in addition to a surgical procedure.

Source: PVGPATDIS, file of 2026-04-10 (ipg200804.xml).

Assignees

Assignee	Type	Place	Also on furp.org	Source
Ethicon Endo-Surgery, Inc. 1,347 patents	US company or organization	Cincinnati, OH	ETHICON ENDO-SURGERY. INC. State business registration EXACT high confidence: identical full name and state	PVGPATDIS, file of 2026-04-10
The General Hospital Corporation 1,995 patents	US company or organization	Boston, MA		PVGPATDIS, file of 2026-04-10
President and Fellows of Harvard College 2,238 patents	US company or organization	Cambridge, MA	Harvard University College or university EXACT high confidence: through the nonprofit with the college's EIN (identical full name and state) PRESIDENT & FELLOWS OF HARVARD COLLEGE Form D issuer EXACT high confidence: identical full name and state PRESIDENT AND FELLOWS OF HARVARD COLLEGE Federal lobbying client EXACT high confidence: identical full name and state PRESIDENT AND FELLOWS OF HARVARD COLLEGE Nonprofit EXACT high confidence: identical full name and state	PVGPATDIS, file of 2026-04-10

Inventors

Inventor	Place	Patents	Source
Lee M. Kaplan	Wellesley, MA	19	PVGPATDIS, file of 2026-04-10
Alice P. Liou	Boston, MA	7	PVGPATDIS, file of 2026-04-10
Peter J. Turnbaugh	Somerville, MA	6	PVGPATDIS, file of 2026-04-10
Jason L. Harris	Lebanon, OH	1286	PVGPATDIS, file of 2026-04-10

CPC categories

Subclass	Category	First group	Source
A61K	Preparations for medical, dental or toiletry purposes	A61K35/74	PVGPATDIS, file of 2026-04-10
A61P	Specific therapeutic activity of chemical compounds or medicinal preparations	A61P1/16	PVGPATDIS, file of 2026-04-10
C12Q	Measuring or testing processes involving enzymes, nucleic acids or microorganisms ; compositions or test papers therefor; processes of preparing such compositions; condition-responsive control in microbiological or enzymological processes	C12Q1/689	PVGPATDIS, file of 2026-04-10
Y02A	Technologies for adaptation to climate change	Y02A50/30	PVGPATDIS, file of 2026-04-10

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

Recorded	What	From	To	Reel/frame	Source
2026-05-29	Security interest Security interest Security interest	PENDULUM THERAPEUTICS, INC. signed 2026-05-29	FIRST-CITIZENS BANK & TRUST COMPANY, AS AGENT SAN FRANCISCO, CA	74795/730	PASDL, file of 2026-10-15
2024-10-28	Name change Change of name	JOHNSON & JOHNSON CONSUMER INC. signed 2024-10-28	KENVUE BRANDS LLC SUMMIT, NJ	69267/143	PASDL, file of 2026-10-15
2023-01-19	Correction Certificate of conversion	JOHNSON & JOHNSON CONSUMER INC. signed 2023-01-03	JOHNSON & JOHNSON CONSUMER INC. SKILLMAN, NJ	62438/521	PASDL, file of 2026-10-15
2023-01-19	Assignment Assignment of assignor's interest	JOHNSON & JOHNSON CONSUMER INC. signed 2023-01-02	JOHNSON & JOHNSON CONSUMER INC. SKILLMAN, NJ	62438/372	PASDL, file of 2026-10-15
2023-01-11	Assignment Assignment of assignor's interest	ETHICON ENDO-SURGERY, INC. signed 2023-01-09	JOHNSON & JOHNSON CONSUMER INC. SKILLMAN, NJ	62341/767	PASDL, file of 2026-10-15
2022-01-18	Security interest Security interest Security interest	PENDULUM THERAPEUTICS, INC. signed 2021-12-31	TRINITY CAPITAL INC. PHOENIX, AZ	58678/276	PASDL, file of 2026-10-15
2020-10-21	Assignment Quitclaim assignment	THE GENERAL HOSPITAL CORPORATION D/B/A MASSACHUSETTS GENERAL HOSPITAL signed 2014-06-24	TURNBAUGH, PETER J. SAN FRANCISCO, CA	54171/725	PASDL, file of 2026-10-15
2020-10-21	Assignment Assignment of assignor's interest	TURNBAUGH, PETER J. signed 2014-10-20	PRESIDENT AND FELLOWS OF HARVARD COLLEGE CAMBRIDGE, MA	54128/957	PASDL, file of 2026-10-15
2020-10-21	Assignment Assignment of assignor's interest	HARRIS, JASON L. signed 2013-03-13	ETHICON ENDO-SURGERY, INC. CINCINNATI, OH	54128/664	PASDL, file of 2026-10-15
2020-10-21	Assignment Assignment of assignor's interest	KAPLAN, LEE M. signed 2013-03-13 LIOU, ALICE P. signed 2013-03-27 TURNBAUGH, PETER J. signed 2013-03-13	THE GENERAL HOSPITAL CORPORATION D/B/A MASSACHUSETTS GENERAL HOSPITAL BOSTON, MA	54128/519	PASDL, file of 2026-10-15

Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.