Patents
US 10729672 B2: Antineoplastic combinations with mTOR inhibitor, trastuzumab and/or HKI-272
- Granted
- 2020-08-04
- Filed
- 2013-04-30 application 13874147
- Type
- Utility · 14 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
A combination of temsirolimus and trastuzumab in the treatment of cancer is provided. A combination of temsirolimus and HKI-272 is provided. A combination of a trastuzumab and a HKI-272 is also provided. Regimens and kits for treatment of metastatic breast cancer, containing trastuzumab, temsirolimus and/or HKI-272, optionally in combination with other anti-neoplastic agents, or immune modulators are described.
Source: PVGPATDIS, file of 2026-04-10 (ipg200804.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Wyeth, LLC 476 patents | US company or organization | New York, NY | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Laurence Moore | Newton, MA | 1 | PVGPATDIS, file of 2026-04-10 | |
| Charles Michael Zacharchuk | Westford, MA | 6 | PVGPATDIS, file of 2026-04-10 | |
| Sridhar Krishna Rabindran | Chestnut Ridge, NY | 3 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K31/337 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P35/00 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2014-06-12 | Name change Change of name | WYETH signed 2009-11-09 | WYETH LLC NEW YORK, NY | 33136/667 | ECORSEXC, file of 2026-09-25 |
| 2014-06-12 | Assignment Assignment of assignor's interest | MOORE, LAURENCE signed 2006-10-18 ZACHARCHUK, CHARLES signed 2006-10-18 RABINDRAN, SRIDHAR K. signed 2006-10-20 | WYETH MADISON, NJ | 33090/805 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.