Patents
US 10654863 B2: Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof
- Granted
- 2020-05-19
- Filed
- 2018-02-21 application 15901828
- Type
- Utility · 46 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The presently described technology provides methods of treating a patient having moderate to severe pain, narcotic or opioid abuse or narcotic or opioid withdrawal. The presently described methods are carried out by comprising administering to the patient a pharmaceutically effective amount of a composition comprising acetaminophen and benzoate-hydrocodone hydrochloride. The composition has reduced side effects when compared with unconjugated hydrocodone.
Source: PVGPATDIS, file of 2026-04-10 (ipg200519.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| KEMPHARM, INC. 57 patents | US company or organization | Four Corners, FL | KEMPHARM, INC Form D issuer EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Travis Mickle | Kissimmee, FL | 83 | PVGPATDIS, file of 2026-04-10 | |
| Sven Guenther | Coralville, IA | 63 | PVGPATDIS, file of 2026-04-10 | |
| Christal Mickle | Kissimmee, FL | 18 | PVGPATDIS, file of 2026-04-10 | |
| Guochen Chi | Coralville, IA | 41 | PVGPATDIS, file of 2026-04-10 | |
| Jaroslaw Kanski | Blacksburg, VA | 30 | PVGPATDIS, file of 2026-04-10 | |
| Andrea K. Martin | Fincastle, VA | 30 | PVGPATDIS, file of 2026-04-10 | |
| Bindu Bera | Blacksburg, VA | 29 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07D | Heterocyclic compounds | C07D489/02 | PVGPATDIS, file of 2026-04-10 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K9/0019 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P25/30 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2026-03-13 | Release of security interest Release of security interest | ALTER DOMUS (US) LLC signed 2026-03-12 | ZEVRA THERAPEUTICS, INC. CELEBRATION, FL | 75080/907 | PASDL, file of 2026-10-15 |
| 2024-04-08 | Security interest Security interest Security interest | ZEVRA THERAPEUTICS, INC. signed 2024-04-05 | ALTER DOMUS (US) LLC CHICAGO, IL | 67040/637 | PASDL, file of 2026-10-15 |
| 2024-02-23 | Name change Change of name | KEMPHARM, INC. signed 2023-02-21 | ZEVRA THERAPEUTICS, INC. CELEBRATION, FL | 66664/108 | PASDL, file of 2026-10-15 |
| 2018-03-16 | Assignment Assignment of assignor's interest | MICKLE, CHRISTAL signed 2018-02-28 MICKLE, TRAVIS signed 2018-02-28 CHI, GUOCHEN signed 2018-03-02 GUENTHER, SVEN signed 2018-03-02 BERA, BINDU signed 2018-03-05 KANSKI, JAROSLAW signed 2018-03-05 MARTIN, ANDREA K signed 2018-03-05 | KEMPHARM, INC. CORALVILLE, IA | 45254/754 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.