Patents
US 10618896 B2: Alkyl chain modified imidazoquinoline TLR7/8 agonist compounds and uses thereof
- Granted
- 2020-04-14
- Filed
- 2018-08-21 application 16107605
- Type
- Utility · 15 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Disclosed are alkyl chain modified 1H-imidazoquinoline compounds, derivatives and analogs thereof, as Toll-like receptor-7 and -8 agonists for enhancing immune responses. Also provided are methods of making pharmaceutical compositions containing these compounds. The present disclosure also describes methods of use for the alkyl chain modified 1H-imidazoquinoline compounds, derivatives and analogs thereof, and pharmaceutical compositions containing these compounds for the treatment of disease in a subject.
Source: PVGPATDIS, file of 2026-04-10 (ipg200414.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| DYNAVAX TECHNOLOGIES CORPORATION 50 patents | US company or organization | Berkeley, CA | DYNAVAX TECHNOLOGIES CORP SEC filer FUZZY low confidence: same name (legal endings aside), one of each nationally | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Stewart Chipman | Bainbridge Island, WA | 6 | PVGPATDIS, file of 2026-04-10 | |
| John DeMattei | Berthoud, CO | 20 | PVGPATDIS, file of 2026-04-10 | |
| Radwan Kiwan | Richmond, CA | 8 | PVGPATDIS, file of 2026-04-10 | |
| Melissa A. KACHURA | Berkeley, CA | 3 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07D | Heterocyclic compounds | C07D471/04 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P31/00 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2018-08-30 | Assignment Assignment of assignor's interest | CHIPMAN, STEWART D. signed 2018-08-23 DEMATTEI, JOHN signed 2018-08-24 KIWAN, RADWAN signed 2018-08-23 KACHURA, MELISSA A. signed 2018-08-23 | DYNAVAX TECHNOLOGIES CORPORATION BERKELEY, CA | 46758/145 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.