Patents

US 10605705 B2: Cell-based composite materials with programmed structures and functions

Granted
2020-03-31
Filed
2018-04-11 application 15950979
Type
Utility · 12 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

The present invention is directed to the use of silicic acid to transform biological materials, including cellular architecture into inorganic materials to provide biocomposites (nanomaterials) with stabilized structure and function. In the present invention, there has been discovered a means to stabilize the structure and function of biological materials, including cells, biomolecules, peptides, proteins (especially including enzymes), lipids, lipid vesicles, polysaccharides, cytoskeletal filaments, tissue and organs with silicic acid such that these materials may be used as biocomposites. In many instances, these materials retain their original biological activity and may be used in harsh conditions which would otherwise destroy the integrity of the biological material. In certain instances, these biomaterials may be storage stable for long periods of time and reconstituted after storage to return the biological material back to its original form. In addition, by exposing an entire cell to form CSCs, the CSCs may function to provide a unique system to study enzymes or a cascade of enzymes which are otherwise unavailable.

Source: PVGPATDIS, file of 2026-04-10 (ipg200331.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
National Technology & Engineering Solutions of Sandia, LLC 1,085 patentsUS company or organizationAlbuquerque, NMPVGPATDIS, file of 2026-04-10
STC.UNM 475 patentsUS company or organizationAlbuquerque, NMPVGPATDIS, file of 2026-04-10

Inventors

InventorPlacePatentsPerson pageSource
Bryan James KaehrAlbuquerque, NM20PVGPATDIS, file of 2026-04-10
C. Jeffrey BrinkerAlbuquerque, NM27PVGPATDIS, file of 2026-04-10
Jason L. TownsonSeattle, WA4PVGPATDIS, file of 2026-04-10

CPC categories

SubclassCategoryFirst groupSource
G01NInvestigating or analysing materials by determining their chemical or physical propertiesG01N1/2806PVGPATDIS, file of 2026-04-10
C08KUse of inorganic or non-macromolecular organic substances as compounding ingredientsC08K3/36PVGPATDIS, file of 2026-04-10
C12NMicroorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture mediaC12N11/14PVGPATDIS, file of 2026-04-10

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

No recorded assignments or security interests on file for this patent.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.