Patents
US 10596162 B2: Method for treating gefitinib resistant cancer
- Granted
- 2020-03-24
- Filed
- 2016-07-11 application 15207349
- Type
- Utility · 4 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present invention is directed to methods for the treatment of gefitinib and/or erlotinib resistant cancer. An individual with cancer is monitored for cancer progression following treatment with gefitinib and/or erlotinib. Progression of the cancer is indicative that the cancer is resistant to gefitinib and/or erlotinib. Once progression of cancer is noted, the subject is administered a pharmaceutical composition comprising an irreversible epidermal growth factor receptor (EGFR) inhibitor. In preferred embodiments, the irreversible EGFR inhibitor is EKB 569, HKI-272 and HKI-357.
Source: PVGPATDIS, file of 2026-04-10 (ipg200324.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Wyeth, LLC 476 patents | US company or organization | New York, NY | PVGPATDIS, file of 2026-04-10 | |
| The General Hospital Corporation 1,995 patents | US company or organization | Boston, MA | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Daniel A. Haber | Sharon, MA | 28 | PVGPATDIS, file of 2026-04-10 | |
| Daphne Winifred Bell | Bethesda, MD | 8 | PVGPATDIS, file of 2026-04-10 | |
| Jeffrey E. Settleman | Newton, MA | 9 | PVGPATDIS, file of 2026-04-10 | |
| Raffaella Sordella | Cold Spring Harbor, NY | 11 | PVGPATDIS, file of 2026-04-10 | |
| Nadia G. Godin-Heymann | Grafton, GB | 1 | PVGPATDIS, file of 2026-04-10 | |
| Eunice L. Kwak | Marlborough, MA | 1 | PVGPATDIS, file of 2026-04-10 | |
| Sridhar Krishna Rabindran | Eagleville, PA | 3 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K31/4709 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P35/00 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2019-10-28 | Name change Change of name | WYETH signed 2009-11-09 | WYETH LLC NEW YORK, NY | 50848/225 | ECORSEXC, file of 2026-09-25 |
| 2019-10-28 | Assignment Assignment of assignor's interest | RABINDRAN, SRIDHAR KRISHNA signed 2007-07-13 | WYETH MADISON, NJ | 50846/307 | ECORSEXC, file of 2026-09-25 |
| 2019-10-28 | Assignment Assignment of assignor's interest | BELL, DAPHNE WINIFRED signed 2006-02-17 GODIN-HEYMANN, NADIA G. signed 2006-02-19 HABER, DANIEL A. signed 2006-02-20 SETTLEMAN, JEFFREY E. signed 2006-02-22 SORDELLA, RAFFAELLA signed 2006-02-23 KWAK, EUNICE L. signed 2006-02-28 | THE GENERAL HOSPITAL CORPORATION BOSTON, MA | 50846/288 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.