Patents

US 10369168 B2: Administration of polynucleotide toll-like receptor 9 agonists for treating cancer

Granted
2019-08-06
Filed
2018-09-25 application 16141828
Type
Utility · 23 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

The present disclosure relates to methods for treating cancer by intrapulmonary administration of a polynucleotide Toll-like receptor 9 agonist. The methods of the present disclosure are suitable for treating primary cancer of the lung, as well as metastatic cancer to the lung and extra pulmonary cancers thereof. Additionally, the present disclosure provides polynucleotide Toll-like receptor 9 agonists with immune stimulatory and toxicity profiles suitable for intrapulmonary administration.

Source: PVGPATDIS, file of 2026-04-10 (ipg190806.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
DYNAVAX TECHNOLOGIES CORPORATION 50 patentsUS company or organizationBerkeley, CADYNAVAX TECHNOLOGIES CORP SEC filer FUZZY low confidence: same name (legal endings aside), one of each nationallyPVGPATDIS, file of 2026-04-10

Inventors

InventorPlacePatentsPerson pageSource
Cristiana GuiducciAlbany, CA14PVGPATDIS, file of 2026-04-10
Robert L. CoffmanPortola Valley, CA23PVGPATDIS, file of 2026-04-10

CPC categories

SubclassCategoryFirst groupSource
A61KPreparations for medical, dental or toiletry purposesA61K31/713PVGPATDIS, file of 2026-04-10
A61NElectrotherapy; magnetotherapy; radiation therapy; ultrasound therapyA61N5/00PVGPATDIS, file of 2026-04-10
A61PSpecific therapeutic activity of chemical compounds or medicinal preparationsA61P35/00PVGPATDIS, file of 2026-04-10
C07KPeptidesC07K14/435PVGPATDIS, file of 2026-04-10

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

RecordedWhatFromToReel/frameSource
2019-01-10Assignment
Assignment of assignor's interest
COFFMAN, ROBERT L. signed 2016-07-07
GUIDUCCI, CRISTIANA signed 2016-07-07
DYNAVAX TECHNOLOGIES CORPORATION BERKELEY, CA47961/57ECORSEXC, file of 2026-09-25

Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.