Patents

US 10041943 B2: Methods of using chimeric receptors to identify autoimmune disease

Granted
2018-08-07
Filed
2017-08-21 application 15682247
Type
Utility · 12 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

The present invention provides methods and compositions useful in the diagnosis and management of autoimmune diseases. In particular, the present invention provides improved methods and compositions for the diagnosis and management of Graves' disease. The methods of the present invention not only avoids the need for radioactivity and are much simpler, economical, and rapid than methods traditionally used for the diagnosis of Graves' disease, but also improve upon the sensitivity and detection abilities of previous luciferase-based autoantibody detection assays.

Source: PVGPATDIS, file of 2026-04-10 (ipg180807.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
Diagnostic Hybrids, Inc. 13 patentsUS company or organizationAthens, OHDIAGNOSTIC HYBRIDS, INC. State business registration EXACT high confidence: identical full name and statePVGPATDIS, file of 2026-04-10

Inventors

InventorPlacePatentsPerson pageSource
James L. BrownAthens, OH12PVGPATDIS, file of 2026-04-10

CPC categories

SubclassCategoryFirst groupSource
G01NInvestigating or analysing materials by determining their chemical or physical propertiesG01N33/564PVGPATDIS, file of 2026-04-10
C07KPeptidesC07K14/721PVGPATDIS, file of 2026-04-10
Y10STechnical subjects covered by former uspc cross-reference art collections [xracs] and digestsY10S435/80PVGPATDIS, file of 2026-04-10

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

RecordedWhatFromToReel/frameSource
2022-05-31Release of security interest
Release of security interest
BANK OF AMERICA, N.A. signed 2022-05-27DIAGNOSTIC HYBRIDS, INC. ATHENS, OH60053/211ECORSEXC, file of 2026-09-25
2018-08-31Security interest Security interest
Security interest
DIAGNOSTIC HYBRIDS, INC. signed 2018-08-31BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT CHARLOTTE, NC46767/806ECORSEXC, file of 2026-09-25
2017-09-25Assignment
Assignment of assignor's interest
BROWN, JAMES L. signed 2008-03-20DIAGNOSTIC HYBRIDS, INC. ATHENS, OH43684/493ECORSEXC, file of 2026-09-25

Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.