Patents
US 10022472 B2: Connective-tissue-based or dermal-tissue-based grafts/implants
- Granted
- 2018-07-17
- Filed
- 2016-06-24 application 15192368
- Type
- Utility · 21 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present invention is directed to a composition comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. Also disclosed is a tissue graft or implant comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. The composition and/or tissue graft or implant of the invention is usable in combination with seeded cells, a tissue growth factor, and/or a chemotactic gent to attract a desired cell.
Source: PVGPATDIS, file of 2026-04-10 (ipg180717.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| RTI Surgical, Inc. 21 patents | US company or organization | Alachua, FL | RTI SURGICAL, INC. SEC filer EXACT medium confidence: identical full name, one of each nationally | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| C. Randal Mills | Deltona, FL | 11 | PVGPATDIS, file of 2026-04-10 | |
| John R. Bianchi | Gainesville, FL | 13 | PVGPATDIS, file of 2026-04-10 | |
| Michael R. Roberts | Gainesville, FL | 7 | PVGPATDIS, file of 2026-04-10 | |
| David T. Cheung | Arcadia, CA | 10 | PVGPATDIS, file of 2026-04-10 | |
| Chandrasekaran Nataraj | Gainesville, FL | 9 | PVGPATDIS, file of 2026-04-10 | |
| John W. Howell, Jr. | Gainesville, FL | 7 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61L | Methods or apparatus for sterilising materials or objects in general; disinfection, sterilisation or deodorisation of air; chemical aspects of bandages, dressings, absorbent pads or surgical articles; materials for bandages, dressings, absorbent pads or surgical articles | A61L27/3608 | PVGPATDIS, file of 2026-04-10 |
| A61F | Filters implantable into blood vessels; prostheses; devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents; orthopaedic, nursing or contraceptive devices; fomentation; treatment or protection of eyes or ears; bandages, dressings or absorbent pads; first-aid kits | A61F2/08 | PVGPATDIS, file of 2026-04-10 |
| B33Y | Additive manufacturing, i.e. manufacturing of three-dimensional [3d] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3d printing, stereolithography or selective laser sintering | B33Y80/00 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2025-09-25 | Release of security interest Termination and release of security interest in patents and trademarks | ARES CAPITAL CORPORATION signed 2025-09-25 | RTI SURGICAL INC. D/B/A EVERGEN ALACHUA, FL | 72938/203 | PASDL, file of 2026-10-15 |
| 2020-07-21 | Release of security interest Release of security interest | JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT signed 2020-07-20 | RTI SURGICAL, INC. ALACHUA, FL PIONEER SURGICAL TECHNOLOGY, INC. ALACHUA, FL TUTOGEN MEDICAL, INC. ALACHUA, FL | 53260/398 | PASDL, file of 2026-10-15 |
| 2020-07-20 | Name change Change of name | RTI OEM, LLC signed 2020-07-17 | RTI SURGICAL, INC. PARIS | 53259/146 | PASDL, file of 2026-10-15 |
| 2020-07-20 | Assignment Intellectual property assignment agreement | SURGALIGN SPINE TECHNOLOGIES, INC. (FORMERLY KNOWN AS RTI SURGICAL, INC.) signed 2020-07-17 | RTI OEM, LLC PARIS | 53259/19 | PASDL, file of 2026-10-15 |
| 2020-07-20 | Release of security interest Release of security interest | ARES CAPITAL CORPORATION, AS AGENT signed 2020-07-20 | RTI SURGICAL, INC. ALACHUA, FL PIONEER SURGICAL TECHNOLOGY, INC. ALACHUA, FL TUTOGEN MEDICAL, INC. ALACHUA, FL PARADIGM SPINE, LLC NEW YORK, NY FOURTH DIMENSION SPINE, LLC NEW YORK, NY | 53257/652 | PASDL, file of 2026-10-15 |
| 2020-07-20 | Name change Change of name | RTI SURGICAL, INC. signed 2020-07-17 | SURGALIGN SPINE TECHNOLOGIES, INC. DEERFIELD, IL | 53248/432 | PASDL, file of 2026-10-15 |
| 2019-03-08 | Security interest Security interest Security interest | RTI SURGICAL, INC. signed 2019-03-08 PIONEER SURGICAL TECHNOLOGY, INC. signed 2019-03-08 TUTOGEN MEDICAL, INC. signed 2019-03-08 PARADIGM SPINE, LLC signed 2019-03-08 FOURTH DIMENSION SPINE, LLC signed 2019-03-08 | ARES CAPITAL CORPORATION, AS ADMINISTRATIVE AGENT NEW YORK, NY | 48543/505 | PASDL, file of 2026-10-15 |
| 2018-07-20 | Assignment Assignment of assignor's interest | MILLS, C. RANDAL signed 2005-11-17 BIANCHI, JOHN R. signed 2005-05-05 ROBERTS, MICHAEL R. signed 2005-11-17 CHEUNG, DAVID T. signed 2005-12-19 NATARAJ, CHANDRASEKARAN signed 2005-05-03 HOWELL, JOHN W., JR. signed 2005-05-03 | REGENERATION TECHNOLOGIES, INC. ALACHUA, FL | 46410/374 | PASDL, file of 2026-10-15 |
| 2018-06-07 | Release of security interest Release of security interest | TD BANK, N.A., AS ADMINISTRATIVE AGENT signed 2018-06-05 | RTI SURGICAL, INC. ALACHUA, FL | 46327/864 | PASDL, file of 2026-10-15 |
| 2018-06-06 | Security interest Security interest Security interest | RTI SURGICAL, INC. signed 2018-06-05 PIONEER SURGICAL TECHNOLOGY, INC. signed 2018-06-05 TUTOGEN MEDICAL, INC. signed 2018-06-05 | JPMORGAN CHASE BANK, N.A., AS THE ADMINISTRATIVE AGENT CHICAGO, IL | 46303/926 | PASDL, file of 2026-10-15 |
| 2018-02-26 | Merger Merger | REGENERATION TECHNOLOGIES, INC. signed 2008-02-27 | RTI BIOLOGICS, INC. DOVER, DE | 45441/347 | PASDL, file of 2026-10-15 |
| 2018-02-26 | Merger Merger | RTI BIOLOGICS, INC. signed 2013-07-16 | RTI SURGICAL, INC. ALACHUA, FL | 45441/310 | PASDL, file of 2026-10-15 |
| 2018-02-26 | Merger Merger | REGENERATION TECHNOLOGIES, INC. signed 2006-07-17 | REGENERATION TECHNOLOGIES, INC. DOVER, DE | 45038/275 | PASDL, file of 2026-10-15 |
| 2018-02-26 | Assignment Assignment of assignor's interest | MILLS, C. RANDAL signed 2005-11-17 BIANCHI, JOHN R signed 2005-05-05 ROBERTS, MICHAEL R signed 2005-11-17 CHEUNG, DAVID T signed 2005-12-19 NATARAJ, CHANDRASEKARAN signed 2005-05-03 HOWELL, JOHN W, JR. signed 2005-05-03 | REGENERATION TECHNOLOGIES, INC. ALACHUA, FL | 45038/183 | PASDL, file of 2026-10-15 |
| 2017-08-20 | Security interest Security interest Security interest | RTI SURGICAL, INC. signed 2017-07-18 | TD BANK, N.A. CHERRY HILL, NJ | 43608/874 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.