NEW YORK GENOME CENTER INC: Form 990, tax year 2016

View the entire original 990 at ProPublica ↗

Organization: NEW YORK GENOME CENTER INC (EIN 80-0631734)
Tax period: 2016-01-01 to 2016-12-31
Filed: 2017-11-14
IRS object ID: 201743189349306454
Schema version: 2016v3.1
Source: Download XML · Original 990 at ProPublica

Every field in the e-filed return. Faint text is the IRS element name, for citing.

Return header
Form 990
Schedule A
Schedule B
Schedule C
Schedule D
Schedule G
Schedule I
Schedule J
Schedule O

Return header ReturnHeader

Field	Value	IRS element (for citing)
Return	2017-11-14T13:35:14-06:00	ReturnTs
Tax Period End	2016-12-31	TaxPeriodEndDt

Preparer Firm PreparerFirmGrp

Preparer Firm Name PreparerFirmName

Field	Value	IRS element (for citing)
Business Name Line1	KPMG LLP	BusinessNameLine1Txt

Preparer US Address PreparerUSAddress

Field	Value	IRS element (for citing)
Address Line1	345 Park Avenue	AddressLine1Txt
City	New York	CityNm
State Abbreviation	NY	StateAbbreviationCd
ZIP	101540102	ZIPCd

Field	Value	IRS element (for citing)
Return Type	990	ReturnTypeCd
Tax Period Begin	2016-01-01	TaxPeriodBeginDt

Filer Filer

Field	Value	IRS element (for citing)
EIN	800631734	EIN

Business Name BusinessName

Field	Value	IRS element (for citing)
Business Name Line1	NEW YORK GENOME CENTER INC	BusinessNameLine1Txt

Field	Value	IRS element (for citing)
In Care Of	% CHRISTOPHER DUIGNAN	InCareOfNm
Business Name Control	NEWY	BusinessNameControlTxt
Phone	6469777000	PhoneNum

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	101 AVENUE OF THE AMERICAS	AddressLine1Txt
City	NEW YORK	CityNm
State Abbreviation	NY	StateAbbreviationCd
ZIP	10013	ZIPCd

Business Officer BusinessOfficerGrp

Field	Value	IRS element (for citing)
Person	CHRIS DUIGNAN	PersonNm
Person Title	VP FINANCE	PersonTitleTxt
Phone	6469777000	PhoneNum
Signature	2017-11-14	SignatureDt
Discuss With Paid Preparer	Yes (true)	DiscussWithPaidPreparerInd

Preparer Person PreparerPersonGrp

Field	Value	IRS element (for citing)
Preparer Person	DEVIN L DUNCAN	PreparerPersonNm
PTIN	P01249521	PTIN
Phone	2127589700	PhoneNum
Preparation	2017-11-08	PreparationDt

Filing Security Information FilingSecurityInformation

IP Address IPAddress

Field	Value	IRS element (for citing)
I Pv4 Address	167.68.102.5	IPv4AddressTxt

Field	Value	IRS element (for citing)
Federal Original Submission Id	13407320173185000048	FederalOriginalSubmissionId
Federal Original Submission Id	2017-11-14	FederalOriginalSubmissionIdDt
Filing License Type	P	FilingLicenseTypeCd
At Submission Creation Device Id	0D7119A55B03D1977737C3E9AB8A10DDBEE9119B	AtSubmissionCreationDeviceId
At Submission Filing Device Id	864472CFA5603F93919C1814BAA1FB0991BE5F91	AtSubmissionFilingDeviceId

Field	Value	IRS element (for citing)
Tax	2016	TaxYr
Build TS	2017-02-10 21:41:12Z	BuildTS

Form 990 IRS990

Field	Value	IRS element (for citing)
Principal Officer	CHERYL MOORE	PrincipalOfficerNm

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	101 AVENUE OF THE AMERICAS	AddressLine1Txt
City	NEW YORK	CityNm
State Abbreviation	NY	StateAbbreviationCd
ZIP	10013	ZIPCd

Field	Value	IRS element (for citing)
Gross Receipts	$132,356,996	GrossReceiptsAmt
Group Return For Affiliates	false	GroupReturnForAffiliatesInd
Organization501c3	Yes (X)	Organization501c3Ind
Website Address	www.nygenome.org	WebsiteAddressTxt
Type Of Organization Corp	Yes (X)	TypeOfOrganizationCorpInd
Formation	2010	FormationYr
Legal Domicile State	DE	LegalDomicileStateCd
Activity Or Mission	NYGC IS AN INDEPENDENT, NONPROFIT ACADEMIC RESEARCH INSTITUTION AT THE FOREFRONT OF TRANSFORMING BIOMEDICAL RESEARCH AND CLINICAL CARE.	ActivityOrMissionDesc
Voting Members Governing Body	28	VotingMembersGoverningBodyCnt
Voting Members Independent	26	VotingMembersIndependentCnt
Total Employee	230	TotalEmployeeCnt
Total Volunteers	28	TotalVolunteersCnt
Total Gross UBI	$840,279	TotalGrossUBIAmt
Net Unrelated Bus Txbl Incm	-$19,285	NetUnrelatedBusTxblIncmAmt
PY Contributions Grants	$61,060,764	PYContributionsGrantsAmt
CY Contributions Grants	$94,901,046	CYContributionsGrantsAmt
PY Program Service Revenue	$17,719,082	PYProgramServiceRevenueAmt
CY Program Service Revenue	$37,095,198	CYProgramServiceRevenueAmt
PY Investment Income	$840,757	PYInvestmentIncomeAmt
CY Investment Income	$23,269	CYInvestmentIncomeAmt
PY Other Revenue	$182,495	PYOtherRevenueAmt
CY Other Revenue	$58,024	CYOtherRevenueAmt
PY Total Revenue	$79,803,098	PYTotalRevenueAmt
CY Total Revenue	$132,077,537	CYTotalRevenueAmt
PY Grants And Similar Paid	$27,788	PYGrantsAndSimilarPaidAmt
CY Grants And Similar Paid	$444,802	CYGrantsAndSimilarPaidAmt
PY Benefits Paid To Members	$0	PYBenefitsPaidToMembersAmt
CY Benefits Paid To Members	$0	CYBenefitsPaidToMembersAmt
PY Salaries Comp Emp Bnft Paid	$22,326,706	PYSalariesCompEmpBnftPaidAmt
CY Salaries Comp Emp Bnft Paid	$32,325,804	CYSalariesCompEmpBnftPaidAmt
PY Total Prof Fndrsng Expns	$1,450	PYTotalProfFndrsngExpnsAmt
CY Total Prof Fndrsng Expns	$130,033	CYTotalProfFndrsngExpnsAmt
CY Total Fundraising Expense	$1,097,140	CYTotalFundraisingExpenseAmt
PY Other Expenses	$53,944,287	PYOtherExpensesAmt
CY Other Expenses	$65,312,805	CYOtherExpensesAmt
PY Total Expenses	$76,300,231	PYTotalExpensesAmt
CY Total Expenses	$98,213,444	CYTotalExpensesAmt
PY Revenues Less Expenses	$3,502,867	PYRevenuesLessExpensesAmt
CY Revenues Less Expenses	$33,864,093	CYRevenuesLessExpensesAmt
Total Assets BOY	$110,178,881	TotalAssetsBOYAmt
Total Assets EOY	$122,070,905	TotalAssetsEOYAmt
Total Liabilities BOY	$104,841,816	TotalLiabilitiesBOYAmt
Total Liabilities EOY	$82,869,747	TotalLiabilitiesEOYAmt
Net Assets Or Fund Balances BOY	$5,337,065	NetAssetsOrFundBalancesBOYAmt
Net Assets Or Fund Balances EOY	$39,201,158	NetAssetsOrFundBalancesEOYAmt
Info In Schedule O Part III	Yes (X)	InfoInScheduleOPartIIIInd
Mission	OPERATE A STATE-OF-THE-ART, WORLD CLASS GENOME SEQUENCING, BIOINFORMATICS AND RESEARCH CENTER IN NEW YORK CITY. FOR MORE INFORMATION, SEE SCHEDULE O.	MissionDesc
Significant New Program Srvc	Yes (true)	SignificantNewProgramSrvcInd
Significant Change	false	SignificantChangeInd
Expense	$41,136,738	ExpenseAmt
Revenue	$27,739,608	RevenueAmt
Desc	RESEARCH SEQUENCING IN 2016, NYGC sequenced 20,000 whole genome samples, completed 1,000 projects, and collaborated with 260 investigators from 89 institutions worldwide. Included in these statistics are 5,000 whole genomes that were sequenced for National Heart, Lung and Blood Institute Trans-omics for Precision Medicine program. As of December 2016, the NYGC facility contained 16 Illumina HiSeq X instruments and 12 Illumina HiSeq 2500 instruments. FOR MORE INFORMATION, SEE SCHEDULE O.	Desc

Prog Srvc Accom Acty2 ProgSrvcAccomActy2Grp

Field	Value	IRS element (for citing)
Expense	$25,689,992	ExpenseAmt
Grant	$444,802	GrantAmt
Revenue	$5,149,401	RevenueAmt
Desc	RESEARCH Our research scientists and faculty are exploring the genomic contributions to human disease, both in their own projects and through collaborations. NYGC researchers have projects underway in cancer, including lung, liver, breast and melanoma; neurodegenerative diseases, focusing on ALS; and autism, among many others. Our bioinformatics scientists play a leadership role in the complex analysis of datasets, including integrating and harmonizing clinical and genomic data necessary for advanced research. FOR MORE INFORMATION, SEE SCHEDULE O.	Desc

Prog Srvc Accom Acty3 ProgSrvcAccomActy3Grp

Field	Value	IRS element (for citing)
Expense	$4,242,468	ExpenseAmt
Revenue	$4,206,189	RevenueAmt
Desc	CLINICAL SEQUENCING - NYGCs Clinical Sequencing Laboratory offers tests that are intended to further the mission of translating genomic research into clinical solutions for serious disease. In 2016, the NYGC received conditional approval from the NYS DOH for constitutional whole genome sequencing for undiagnosed disease, as well as those patients who are seeking predispositional genetic testing. FOR MORE INFORMATION, SEE SCHEDULE O.	Desc

Field	Value	IRS element (for citing)
Total Program Service Expenses	$71,069,198	TotalProgramServiceExpensesAmt
Described In Section501c3	Yes (true)	DescribedInSection501c3Ind
Schedule B Required	Yes (true)	ScheduleBRequiredInd
Political Campaign Acty	false	PoliticalCampaignActyInd
Lobbying Activities	Yes (true)	LobbyingActivitiesInd
Subject To Proxy Tax	false	SubjectToProxyTaxInd
Donor Advised Fund	false	DonorAdvisedFundInd
Conservation Easements	false	ConservationEasementsInd
Collections Of Art	false	CollectionsOfArtInd
Credit Counseling	false	CreditCounselingInd
Temp Or Permanent Endowments	false	TempOrPermanentEndowmentsInd
Report Land Building Equipment	Yes (true)	ReportLandBuildingEquipmentInd
Report Investments Other Sec	false	ReportInvestmentsOtherSecInd
Report Program Related Invst	false	ReportProgramRelatedInvstInd
Report Other Assets	Yes (true)	ReportOtherAssetsInd
Report Other Liabilities	Yes (true)	ReportOtherLiabilitiesInd
Include FIN48 Footnote	Yes (true)	IncludeFIN48FootnoteInd
Independent Audit Fincl Stmt	Yes (true)	IndependentAuditFinclStmtInd
Consolidated Audit Fincl Stmt	false	ConsolidatedAuditFinclStmtInd
School Operating	false	SchoolOperatingInd
Foreign Office	false	ForeignOfficeInd
Foreign Activities	false	ForeignActivitiesInd
More Than5000 K To Org	false	MoreThan5000KToOrgInd
More Than5000 K To Individuals	false	MoreThan5000KToIndividualsInd
Professional Fundraising	Yes (true)	ProfessionalFundraisingInd
Fundraising Activities	false	FundraisingActivitiesInd
Gaming Activities	false	GamingActivitiesInd
Operate Hospital	false	OperateHospitalInd
Grants To Organizations	Yes (true)	GrantsToOrganizationsInd
Grants To Individuals	false	GrantsToIndividualsInd
Schedule J Required	Yes (true)	ScheduleJRequiredInd
Tax Exempt Bonds	false	TaxExemptBondsInd
Engaged In Excess Benefit Trans	false	EngagedInExcessBenefitTransInd
PY Excess Benefit Trans	false	PYExcessBenefitTransInd
Loan Outstanding	false	LoanOutstandingInd
Grant To Related Person	false	GrantToRelatedPersonInd
Business Rln With Org Mem	false	BusinessRlnWithOrgMemInd
Business Rln With Fam Mem	false	BusinessRlnWithFamMemInd
Business Rln With Officer Ent	false	BusinessRlnWithOfficerEntInd
Deductible Non Cash Contri	false	DeductibleNonCashContriInd
Deductible Art Contribution	false	DeductibleArtContributionInd
Terminate Operations	false	TerminateOperationsInd
Partial Liquidation	false	PartialLiquidationInd
Disregarded Entity	false	DisregardedEntityInd
Related Entity	false	RelatedEntityInd
Related Organization Ctrl Ent	false	RelatedOrganizationCtrlEntInd
Trnsfr Exmpt Non Chrtbl Rltd Org	false	TrnsfrExmptNonChrtblRltdOrgInd
Activities Conducted Prtshp	false	ActivitiesConductedPrtshpInd
Schedule O Required	Yes (true)	ScheduleORequiredInd
IRP Document	74	IRPDocumentCnt
IRP Document W2 G	0	IRPDocumentW2GCnt
Backup Wthld Compliance	Yes (true)	BackupWthldComplianceInd
Employee	230	EmployeeCnt
Employment Tax Returns Filed	Yes (true)	EmploymentTaxReturnsFiledInd
Unrelated Bus Incm Over Limit	Yes (true)	UnrelatedBusIncmOverLimitInd
Form990 T Filed	Yes (true)	Form990TFiledInd
Foreign Financial Account	false	ForeignFinancialAccountInd
Prohibited Tax Shelter Trans	false	ProhibitedTaxShelterTransInd
Taxable Party Notification	false	TaxablePartyNotificationInd
Nondeductible Contributions	false	NondeductibleContributionsInd
Quid Pro Quo Contributions	false	QuidProQuoContributionsInd
Form8282 Property Disposed Of	false	Form8282PropertyDisposedOfInd
Rcv Fnds To Pay Prsnl Bnft Cntrct	false	RcvFndsToPayPrsnlBnftCntrctInd
Pay Premiums Prsnl Bnft Cntrct	false	PayPremiumsPrsnlBnftCntrctInd
Indoor Tanning Services	false	IndoorTanningServicesInd
Info In Schedule O Part VI	Yes (X)	InfoInScheduleOPartVIInd
Governing Body Voting Members	28	GoverningBodyVotingMembersCnt
Independent Voting Member	26	IndependentVotingMemberCnt
Family Or Business Rln	false	FamilyOrBusinessRlnInd
Delegation Of Mgmt Duties	false	DelegationOfMgmtDutiesInd
Change To Org Documents	Yes (true)	ChangeToOrgDocumentsInd
Material Diversion Or Misuse	false	MaterialDiversionOrMisuseInd
Members Or Stockholders	Yes (true)	MembersOrStockholdersInd
Election Of Board Members	Yes (true)	ElectionOfBoardMembersInd
Decisions Subject To Approva	Yes (true)	DecisionsSubjectToApprovaInd
Minutes Of Governing Body	Yes (true)	MinutesOfGoverningBodyInd
Minutes Of Committees	Yes (true)	MinutesOfCommitteesInd
Officer Mailing Address	false	OfficerMailingAddressInd
Local Chapters	false	LocalChaptersInd
Form990 Provided To Gvrn Body	Yes (true)	Form990ProvidedToGvrnBodyInd
Conflict Of Interest Policy	Yes (true)	ConflictOfInterestPolicyInd
Annual Disclosure Covered Prsn	Yes (true)	AnnualDisclosureCoveredPrsnInd
Regular Monitoring Enfrc	Yes (true)	RegularMonitoringEnfrcInd
Whistleblower Policy	Yes (true)	WhistleblowerPolicyInd
Document Retention Policy	Yes (true)	DocumentRetentionPolicyInd
Compensation Process CEO	Yes (true)	CompensationProcessCEOInd
Compensation Process Other	Yes (true)	CompensationProcessOtherInd
Investment In Joint Venture	Yes (true)	InvestmentInJointVentureInd
Written Policy Or Procedure	Yes (true)	WrittenPolicyOrProcedureInd
States Where Copy Of Return Is Fld	CT	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	FL	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	NJ	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	NY	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	OK	StatesWhereCopyOfReturnIsFldCd
Upon Request	Yes (X)	UponRequestInd

Books In Care Of Detail BooksInCareOfDetail

Field	Value	IRS element (for citing)
Person	CHRISTOPHER DUIGNAN	PersonNm
Phone	6469777303	PhoneNum

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	101 AVENUE OF THE AMERICAS 7TH FLO	AddressLine1Txt
City	NEW YORK	CityNm
State Abbreviation	NY	StateAbbreviationCd
ZIP	10013	ZIPCd

Field	Value	IRS element (for citing)
Info In Schedule O Part VII	Yes (X)	InfoInScheduleOPartVIIInd

Form990 Part VII Section A Form990PartVIISectionAGrp (41 entries)

TitleTitleTxt	Average Hours Per WeekAverageHoursPerWeekRt	Average Hours Per Week Rltd OrgAverageHoursPerWeekRltdOrgRt	Individual Trustee Or DirectorIndividualTrusteeOrDirectorInd	Reportable Comp From OrgReportableCompFromOrgAmt	Reportable Comp From Rltd OrgReportableCompFromRltdOrgAmt	Other CompensationOtherCompensationAmt	OfficerOfficerInd	Key EmployeeKeyEmployeeInd	Highest Compensated EmployeeHighestCompensatedEmployeeInd
DAFNA BAR-SAGI PHD
DIRECTOR	1.0	0.0	Yes (X)	$0	$0	$0
RUSSELL L CARSON MBA
DIRECTOR & CO-CHAIR	4.0	0.0	Yes (X)	$0	$0	$0	Yes (X)
DENNIS S CHARNEY MD
DIRECTOR	1.0	0.0	Yes (X)	$0	$0	$0
AUGUSTINE MK CHOI MD
DIRECTOR - EFF. 8/11/16	1.0	0.0	Yes (X)	$0	$0	$0
ROBERT B DARNELL MD PHD
FOUNDING DIR&CEO-THRU 12/31/16	10.0	0.0	Yes (X)	$340,962	$0	$0	Yes (X)
NICHOLAS DONOFRIO
DIRECTOR	1.0	0.0	Yes (X)	$0	$0	$0
JOHN B EHRENKRANZ
DIRECTOR	1.0	0.0	Yes (X)	$0	$0	$0
ANTHONY B EVNIN PHD
DIRECTOR	1.0	0.0	Yes (X)	$0	$0	$0
WILLIAM E FORD
DIRECTOR	1.0	0.0	Yes (X)	$0	$0	$0
LAURIE H GLIMCHER MD
DIRECTOR - THRU 8/11/16	1.0	0.0	Yes (X)	$0	$0	$0
LEE GOLDMAN MD MPH
DIRECTOR	1.0	0.0	Yes (X)	$0	$0	$0
JOHN HAVENS
DIRECTOR / COMMITTEE CHAIR	1.0	0.0	Yes (X)	$0	$0	$0
WESLIE R JANEWAY
DIRECTOR	1.0	0.0	Yes (X)	$0	$0	$0
RICHARD P LIFTON MD PHD
DIRECTOR - EFF. 11/10/16	1.0	0.0	Yes (X)	$0	$0	$0
EDISON T LIU MD
DIRECTOR	1.0	0.0	Yes (X)	$0	$0	$0
TOM MANIATIS PHD
DIRECTOR	1.0	0.0	Yes (X)	$0	$0	$0
CHERYL A MOORE
PRESIDENT & COO - EFF. 1/11/16	40.0	0.0	Yes (X)	$1,275,300	$0	$199,690	Yes (X)
HERB PARDES MD
DIRECTOR & VICE CHAIR	1.0	0.0	Yes (X)	$0	$0	$0
FRANK E RICHARDSON MA JD
DIRECTOR	1.0	0.0	Yes (X)	$0	$0	$0
ARTHUR J SAMBERG
DIRECTOR	1.0	0.0	Yes (X)	$0	$0	$0
IVAN G SEIDENBERG MBA
DIRECTOR & CO-CHAIR	4.0	0.0	Yes (X)	$0	$0	$0	Yes (X)
FRANK V SICA
DIRECTOR	1.0	0.0	Yes (X)	$0	$0	$0
JIM SIMONS PHD
DIRECTOR	1.0	0.0	Yes (X)	$0	$0	$0
STEVEN SINGER ESQ
DIRECTOR	1.0	0.0	Yes (X)	$0	$0	$0
ALLEN M SPIEGEL MD
DIRECTOR	1.0	0.0	Yes (X)	$0	$0	$0
SAMUEL L STANLEY JR MD
DIRECTOR	1.0	0.0	Yes (X)	$0	$0	$0
BRUCE STILLMAN PHD
DIRECTOR	1.0	0.0	Yes (X)	$0	$0	$0
MARC TESSIER-LAVIGNE PHD
DIRECTOR - THRU 8/31/16	1.0	0.0	Yes (X)	$0	$0	$0
CRAIG B THOMPSON MD
DIRECTOR	1.0	0.0	Yes (X)	$0	$0	$0
KEVIN J TRACEY MD
DIRECTOR	1.0	0.0	Yes (X)	$0	$0	$0
CHRIS DUIGNAN
VP, FINANCE	40.0	0.0		$299,329	$0	$43,017	Yes (X)
CAROL ASHE
CHIEF BUSINESS OFFICER	40.0	0.0		$456,449	$0	$13,367		Yes (X)
HAROLD SWERDLOW PHD
VICE PRESIDENT OF SEQUENCING	40.0	0.0		$405,211	$0	$39,318		Yes (X)
KATHLEEN MCGOVERN KEARNS
VICE PRESIDENT, DEV'T & COMM	40.0	0.0		$395,415	$0	$28,979		Yes (X)
TOBY BLOOM PHD
DEPUTY SCIENTIFIC DIR., INFO.	40.0	0.0		$349,086	$0	$34,729		Yes (X)
MATTHEW J PELO
VP, FINANCIAL STRATEGY & OPS	40.0	0.0		$311,307	$0	$20,726		Yes (X)
ELIZABETH O'BRIEN
VICE PRESIDENT & GEN. COUNSEL	40.0	0.0		$384,832	$0	$37,987			Yes (X)
SHAILAJA GARGEYA
SENIOR DIR. SOFTWARE ENGINEER	40.0	0.0		$286,274	$0	$24,941			Yes (X)
LISA ESCUDERO
VP, HUMAN RESOURCES	40.0	0.0		$244,910	$0	$30,989			Yes (X)
DAYNA M OSCHWALD
SNR. DIR, INFO. PGM MGMT	40.0	0.0		$225,586	$0	$24,998			Yes (X)
JOSEPH PICKRELL
CORE MEMBER, ASST INVESTIGATOR	40.0	0.0		$199,141	$0	$31,188			Yes (X)

Field	Value	IRS element (for citing)
Total Reportable Comp From Org	$5,173,802	TotalReportableCompFromOrgAmt
Tot Reportable Comp Rltd Org	$0	TotReportableCompRltdOrgAmt
Total Other Compensation	$529,929	TotalOtherCompensationAmt
Indiv Rcvd Greater Than100 K	90	IndivRcvdGreaterThan100KCnt
Former Ofcr Employees Listed	false	FormerOfcrEmployeesListedInd
Total Comp Greater Than150 K	Yes (true)	TotalCompGreaterThan150KInd
Compensation From Other Srcs	false	CompensationFromOtherSrcsInd

Contractor Compensation ContractorCompensationGrp (5 entries)

Address Line1ContractorAddress/USAddress/AddressLine1Txt	CityContractorAddress/USAddress/CityNm	State AbbreviationContractorAddress/USAddress/StateAbbreviationCd	ZIPContractorAddress/USAddress/ZIPCd	ServicesServicesDesc	CompensationCompensationAmt
ROBERT DARNELL MD PHD
236 Elderwood Ave	PELHAM	NY	10803	management services	$340,962
GREG HANNON
402 WEST 20TH ST	NEW YORK	NY	10011	research services	$262,581
PRICEWATERHOUSECOOPERS LLP
4040 W BOY SCOUT BLVD	TAMPA	FL	33607	advisory services	$261,663
PJ MECHANICAL SERVICE MAINTENAN
55 BROAD STREET	NEW YORK	NY	10004	engineering services	$526,160
SPENCERSTUART
PO BOX 98991	CHICAGO	IL	60693	recruitment services	$326,571

Field	Value	IRS element (for citing)
Cntrct Rcvd Greater Than100 K	18	CntrctRcvdGreaterThan100KCnt
Membership Dues	$3,035,000	MembershipDuesAmt
Government Grants	$18,272,423	GovernmentGrantsAmt
All Other Contributions	$73,593,623	AllOtherContributionsAmt
Total Contributions	$94,901,046	TotalContributionsAmt

Program Service Revenue ProgramServiceRevenueGrp (3 entries)

DescDesc	BusinessBusinessCd	Total Revenue ColumnTotalRevenueColumnAmt	Related Or Exempt Func IncomeRelatedOrExemptFuncIncomeAmt	Unrelated Business RevenueUnrelatedBusinessRevenueAmt
RESEARCH SEQUENCING	541700	$27,739,608	$26,899,329	$840,279
RESEARCH	541700	$5,149,401	$5,149,401
CLINICAL SEQUENCING	541700	$4,206,189	$4,206,189

Field	Value	IRS element (for citing)
Total Program Service Revenue	$37,095,198	TotalProgramServiceRevenueAmt

Investment Income InvestmentIncomeGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$23,269	TotalRevenueColumnAmt
Exclusion	$23,269	ExclusionAmt

Incm From Invest Bond Proceeds IncmFromInvestBondProceedsGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$0	TotalRevenueColumnAmt

Royalties Revenue RoyaltiesRevenueGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$0	TotalRevenueColumnAmt

Gross Rents GrossRentsGrp

Field	Value	IRS element (for citing)
Real	$279,459	RealAmt

Less Rental Expenses LessRentalExpensesGrp

Field	Value	IRS element (for citing)
Real	$279,459	RealAmt

Rental Income Or Loss RentalIncomeOrLossGrp

Field	Value	IRS element (for citing)
Real	$0	RealAmt
Personal	$0	PersonalAmt

Net Rental Income Or Loss NetRentalIncomeOrLossGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$0	TotalRevenueColumnAmt

Net Gain Or Loss Investments NetGainOrLossInvestmentsGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$0	TotalRevenueColumnAmt

Field	Value	IRS element (for citing)
Fundraising Gross Income	$0	FundraisingGrossIncomeAmt
Fundraising Direct Expenses	$0	FundraisingDirectExpensesAmt

Net Incm From Fundraising Evt NetIncmFromFundraisingEvtGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$0	TotalRevenueColumnAmt

Field	Value	IRS element (for citing)
Gaming Gross Income	$0	GamingGrossIncomeAmt
Gaming Direct Expenses	$0	GamingDirectExpensesAmt

Net Income From Gaming NetIncomeFromGamingGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$0	TotalRevenueColumnAmt

Field	Value	IRS element (for citing)
Gross Sales Of Inventory	$0	GrossSalesOfInventoryAmt
Cost Of Goods Sold	$0	CostOfGoodsSoldAmt

Net Income Or Loss NetIncomeOrLossGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$0	TotalRevenueColumnAmt

Other Revenue Misc OtherRevenueMiscGrp (2 entries)

DescDesc	BusinessBusinessCd	Total Revenue ColumnTotalRevenueColumnAmt	ExclusionExclusionAmt
EVENT SPACE REVENUE	900099	$45,250	$45,250
OTHER REVENUE	900099	$12,774	$12,774

Field	Value	IRS element (for citing)
Other Revenue Total	$58,024	OtherRevenueTotalAmt

Total Revenue TotalRevenueGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$132,077,537	TotalRevenueColumnAmt
Related Or Exempt Func Income	$36,254,919	RelatedOrExemptFuncIncomeAmt
Unrelated Business Revenue	$840,279	UnrelatedBusinessRevenueAmt
Exclusion	$81,293	ExclusionAmt

Grants To Domestic Orgs GrantsToDomesticOrgsGrp

Field	Value	IRS element (for citing)
Total	$444,802	TotalAmt
Program Services	$444,802	ProgramServicesAmt

Grants To Domestic Individuals GrantsToDomesticIndividualsGrp

Field	Value	IRS element (for citing)
Total	$0	TotalAmt

Foreign Grants ForeignGrantsGrp

Field	Value	IRS element (for citing)
Total	$0	TotalAmt

Benefits To Members BenefitsToMembersGrp

Field	Value	IRS element (for citing)
Total	$0	TotalAmt

Comp Current Ofcr Directors CompCurrentOfcrDirectorsGrp

Field	Value	IRS element (for citing)
Total	$4,212,884	TotalAmt
Program Services	$1,160,377	ProgramServicesAmt
Management And General	$2,628,114	ManagementAndGeneralAmt
Fundraising	$424,393	FundraisingAmt

Comp Disqual Persons CompDisqualPersonsGrp

Field	Value	IRS element (for citing)
Total	$0	TotalAmt

Other Salaries And Wages OtherSalariesAndWagesGrp

Field	Value	IRS element (for citing)
Total	$22,347,246	TotalAmt
Program Services	$17,197,015	ProgramServicesAmt
Management And General	$4,915,249	ManagementAndGeneralAmt
Fundraising	$234,982	FundraisingAmt

Pension Plan Contributions PensionPlanContributionsGrp

Field	Value	IRS element (for citing)
Total	$1,008,453	TotalAmt
Program Services	$704,544	ProgramServicesAmt
Management And General	$273,681	ManagementAndGeneralAmt
Fundraising	$30,228	FundraisingAmt

Other Employee Benefits OtherEmployeeBenefitsGrp

Field	Value	IRS element (for citing)
Total	$3,101,863	TotalAmt
Program Services	$2,063,284	ProgramServicesAmt
Management And General	$988,605	ManagementAndGeneralAmt
Fundraising	$49,974	FundraisingAmt

Payroll Taxes PayrollTaxesGrp

Field	Value	IRS element (for citing)
Total	$1,655,358	TotalAmt
Program Services	$1,214,565	ProgramServicesAmt
Management And General	$404,643	ManagementAndGeneralAmt
Fundraising	$36,150	FundraisingAmt

Fees For Services Management FeesForServicesManagementGrp

Field	Value	IRS element (for citing)
Total	$0	TotalAmt

Fees For Services Legal FeesForServicesLegalGrp

Field	Value	IRS element (for citing)
Total	$543,456	TotalAmt
Management And General	$543,456	ManagementAndGeneralAmt

Fees For Services Accounting FeesForServicesAccountingGrp

Field	Value	IRS element (for citing)
Total	$216,051	TotalAmt
Management And General	$216,051	ManagementAndGeneralAmt

Fees For Services Lobbying FeesForServicesLobbyingGrp

Field	Value	IRS element (for citing)
Total	$92,490	TotalAmt
Management And General	$92,490	ManagementAndGeneralAmt

Fees For Services Prof Fundraising FeesForServicesProfFundraising

Field	Value	IRS element (for citing)
Total	$130,033	TotalAmt
Fundraising	$130,033	FundraisingAmt

Fees For Srvc Invst Mgmnt Fees FeesForSrvcInvstMgmntFeesGrp

Field	Value	IRS element (for citing)
Total	$0	TotalAmt

Fees For Services Other FeesForServicesOtherGrp

Field	Value	IRS element (for citing)
Total	$916,621	TotalAmt
Program Services	$481,851	ProgramServicesAmt
Management And General	$427,248	ManagementAndGeneralAmt
Fundraising	$7,522	FundraisingAmt

Advertising AdvertisingGrp

Field	Value	IRS element (for citing)
Total	$229,423	TotalAmt
Program Services	$3,583	ProgramServicesAmt
Management And General	$225,840	ManagementAndGeneralAmt

Office Expenses OfficeExpensesGrp

Field	Value	IRS element (for citing)
Total	$957,505	TotalAmt
Program Services	$235,294	ProgramServicesAmt
Management And General	$721,308	ManagementAndGeneralAmt
Fundraising	$903	FundraisingAmt

Information Technology InformationTechnologyGrp

Field	Value	IRS element (for citing)
Total	$2,638,722	TotalAmt
Program Services	$1,200,828	ProgramServicesAmt
Management And General	$1,433,169	ManagementAndGeneralAmt
Fundraising	$4,725	FundraisingAmt

Royalties RoyaltiesGrp

Field	Value	IRS element (for citing)
Total	$0	TotalAmt

Occupancy OccupancyGrp

Field	Value	IRS element (for citing)
Total	$14,818,660	TotalAmt
Program Services	$9,387,181	ProgramServicesAmt
Management And General	$5,312,166	ManagementAndGeneralAmt
Fundraising	$119,313	FundraisingAmt

Travel TravelGrp

Field	Value	IRS element (for citing)
Total	$519,640	TotalAmt
Program Services	$272,275	ProgramServicesAmt
Management And General	$243,743	ManagementAndGeneralAmt
Fundraising	$3,622	FundraisingAmt

Pymt Travel Entrtnmnt Pub Ofcl PymtTravelEntrtnmntPubOfclGrp

Field	Value	IRS element (for citing)
Total	$0	TotalAmt

Conferences Meetings ConferencesMeetingsGrp

Field	Value	IRS element (for citing)
Total	$267,267	TotalAmt
Program Services	$108,564	ProgramServicesAmt
Management And General	$152,383	ManagementAndGeneralAmt
Fundraising	$6,320	FundraisingAmt

Interest InterestGrp

Field	Value	IRS element (for citing)
Total	$1,014,537	TotalAmt
Program Services	$756,093	ProgramServicesAmt
Management And General	$250,309	ManagementAndGeneralAmt
Fundraising	$8,135	FundraisingAmt

Payments To Affiliates PaymentsToAffiliatesGrp

Field	Value	IRS element (for citing)
Total	$0	TotalAmt

Depreciation Depletion DepreciationDepletionGrp

Field	Value	IRS element (for citing)
Total	$15,234,042	TotalAmt
Program Services	$8,913,997	ProgramServicesAmt
Management And General	$6,289,266	ManagementAndGeneralAmt
Fundraising	$30,779	FundraisingAmt

Insurance InsuranceGrp

Field	Value	IRS element (for citing)
Total	$445,490	TotalAmt
Management And General	$445,490	ManagementAndGeneralAmt

Other Expenses OtherExpensesGrp (4 entries)

DescDesc	TotalTotalAmt	Program ServicesProgramServicesAmt	Management And GeneralManagementAndGeneralAmt	FundraisingFundraisingAmt
DIRECT COST OF SEQUENCING	$23,268,143	$23,268,143
RESEARCH & CLIA	$3,382,423	$3,382,423
RECRUITMENT	$489,725	$118,193	$371,532
ALL OTHER EXPENSE	$278,610	$156,186	$112,363	$10,061

Total Functional Expenses TotalFunctionalExpensesGrp

Field	Value	IRS element (for citing)
Total	$98,213,444	TotalAmt
Program Services	$71,069,198	ProgramServicesAmt
Management And General	$26,047,106	ManagementAndGeneralAmt
Fundraising	$1,097,140	FundraisingAmt

Field	Value	IRS element (for citing)
Info In Schedule O Part X	Yes (X)	InfoInScheduleOPartXInd

Cash Non Interest Bearing CashNonInterestBearingGrp

Field	Value	IRS element (for citing)
BOY	$8,314,331	BOYAmt
EOY	$15,120,314	EOYAmt

Savings And Temp Cash Invst SavingsAndTempCashInvstGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Pledges And Grants Receivable PledgesAndGrantsReceivableGrp

Field	Value	IRS element (for citing)
BOY	$7,904,830	BOYAmt
EOY	$19,131,071	EOYAmt

Accounts Receivable AccountsReceivableGrp

Field	Value	IRS element (for citing)
BOY	$4,256,171	BOYAmt
EOY	$6,687,337	EOYAmt

Receivables From Officers Etc ReceivablesFromOfficersEtcGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Rcvbl From Disqualified Prsn RcvblFromDisqualifiedPrsnGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Oth Notes Loans Receivable Net OthNotesLoansReceivableNetGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Inventories For Sale Or Use InventoriesForSaleOrUseGrp

Field	Value	IRS element (for citing)
BOY	$6,724,235	BOYAmt
EOY	$7,515,459	EOYAmt

Prepaid Expenses Defrd Charges PrepaidExpensesDefrdChargesGrp

Field	Value	IRS element (for citing)
BOY	$4,607,181	BOYAmt
EOY	$2,375,799	EOYAmt

Field	Value	IRS element (for citing)
Land Bldg Equip Cost Or Other Bss	$103,716,928	LandBldgEquipCostOrOtherBssAmt
Land Bldg Equip Accum Deprec	$43,799,525	LandBldgEquipAccumDeprecAmt

Land Bldg Equip Basis Net LandBldgEquipBasisNetGrp

Field	Value	IRS element (for citing)
BOY	$67,303,356	BOYAmt
EOY	$59,917,403	EOYAmt

Investments Pub Traded Sec InvestmentsPubTradedSecGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Investments Other Securities InvestmentsOtherSecuritiesGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Investments Program Related InvestmentsProgramRelatedGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Intangible Assets IntangibleAssetsGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Other Assets Total OtherAssetsTotalGrp

Field	Value	IRS element (for citing)
BOY	$11,068,777	BOYAmt
EOY	$11,323,522	EOYAmt

Total Assets TotalAssetsGrp

Field	Value	IRS element (for citing)
BOY	$110,178,881	BOYAmt
EOY	$122,070,905	EOYAmt

Accounts Payable Accr Expnss AccountsPayableAccrExpnssGrp

Field	Value	IRS element (for citing)
BOY	$5,194,484	BOYAmt
EOY	$14,754,579	EOYAmt

Grants Payable GrantsPayableGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Deferred Revenue DeferredRevenueGrp

Field	Value	IRS element (for citing)
BOY	$7,050,115	BOYAmt
EOY	$13,596,240	EOYAmt

Tax Exempt Bond Liabilities TaxExemptBondLiabilitiesGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Escrow Account Liability EscrowAccountLiabilityGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Loans From Officers Directors LoansFromOfficersDirectorsGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Mortg Notes Pybl Scrd Invst Prop MortgNotesPyblScrdInvstPropGrp

Field	Value	IRS element (for citing)
BOY	$6,411,955	BOYAmt
EOY	$5,543,160	EOYAmt

Unsecured Notes Loans Payable UnsecuredNotesLoansPayableGrp

Field	Value	IRS element (for citing)
BOY	$54,999,000	BOYAmt
EOY	$21,885,110	EOYAmt

Other Liabilities OtherLiabilitiesGrp

Field	Value	IRS element (for citing)
BOY	$31,186,262	BOYAmt
EOY	$27,090,658	EOYAmt

Total Liabilities TotalLiabilitiesGrp

Field	Value	IRS element (for citing)
BOY	$104,841,816	BOYAmt
EOY	$82,869,747	EOYAmt

Field	Value	IRS element (for citing)
Organization Follows SFAS117	Yes (X)	OrganizationFollowsSFAS117Ind

Unrestricted Net Assets UnrestrictedNetAssetsGrp

Field	Value	IRS element (for citing)
BOY	-$5,804,618	BOYAmt
EOY	$17,485,267	EOYAmt

Temporarily Rstr Net Assets TemporarilyRstrNetAssetsGrp

Field	Value	IRS element (for citing)
BOY	$11,141,683	BOYAmt
EOY	$21,715,891	EOYAmt

Permanently Rstr Net Assets PermanentlyRstrNetAssetsGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Total Net Assets Fund Balance TotalNetAssetsFundBalanceGrp

Field	Value	IRS element (for citing)
BOY	$5,337,065	BOYAmt
EOY	$39,201,158	EOYAmt

Tot Liab Net Assets Fund Balance TotLiabNetAssetsFundBalanceGrp

Field	Value	IRS element (for citing)
BOY	$110,178,881	BOYAmt
EOY	$122,070,905	EOYAmt

Field	Value	IRS element (for citing)
Info In Schedule O Part XI	Yes (X)	InfoInScheduleOPartXIInd
Reconcilation Revenue Expnss	$33,864,093	ReconcilationRevenueExpnssAmt
Method Of Accounting Accrual	Yes (X)	MethodOfAccountingAccrualInd
Accountant Compile Or Review	false	AccountantCompileOrReviewInd
FS Audited	Yes (true)	FSAuditedInd

FS Audited Basis FSAuditedBasisGrp

Field	Value	IRS element (for citing)
Separate Basis Fincl Stmt	Yes (X)	SeparateBasisFinclStmtInd

Field	Value	IRS element (for citing)
Audit Committee	Yes (true)	AuditCommitteeInd
Federal Grant Audit Required	Yes (true)	FederalGrantAuditRequiredInd
Federal Grant Audit Performed	Yes (true)	FederalGrantAuditPerformedInd

Schedule A IRS990ScheduleA

Field	Value	IRS element (for citing)
Public Organization170	Yes (X)	PublicOrganization170Ind

Gifts Grants Contri Rcvd170 GiftsGrantsContriRcvd170Grp

Field	Value	IRS element (for citing)
Current Tax Year Minus4 Years	$19,649,601	CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years	$14,419,687	CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years	$52,034,400	CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year	$61,060,764	CurrentTaxYearMinus1YearAmt
Current Tax Year	$94,901,046	CurrentTaxYearAmt
Total	$242,065,498	TotalAmt

Tax Rev Levied Orgnztnl Bnft170 TaxRevLeviedOrgnztnlBnft170Grp

Field	Value	IRS element (for citing)
Total	$0	TotalAmt

Govt Furn Srvc Fclts Vl170 GovtFurnSrvcFcltsVl170Grp

Field	Value	IRS element (for citing)
Total	$0	TotalAmt

Total Calendar Year170 TotalCalendarYear170Grp

Field	Value	IRS element (for citing)
Current Tax Year Minus4 Years	$19,649,601	CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years	$14,419,687	CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years	$52,034,400	CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year	$61,060,764	CurrentTaxYearMinus1YearAmt
Current Tax Year	$94,901,046	CurrentTaxYearAmt
Total	$242,065,498	TotalAmt

Field	Value	IRS element (for citing)
Substantial Contributors Tot	$71,208,018	SubstantialContributorsTotAmt
Public Support Total170	$170,857,480	PublicSupportTotal170Amt

Gross Investment Income170 GrossInvestmentIncome170Grp

Field	Value	IRS element (for citing)
Current Tax Year Minus4 Years	$24,896	CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years	$83,412	CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years	$556,550	CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year	$268,801	CurrentTaxYearMinus1YearAmt
Current Tax Year	$302,728	CurrentTaxYearAmt
Total	$1,236,387	TotalAmt

Unrelated Business Net Incm170 UnrelatedBusinessNetIncm170Grp

Field	Value	IRS element (for citing)
Current Tax Year Minus4 Years	$43,718	CurrentTaxYearMinus4YearsAmt
Total	$43,718	TotalAmt

Other Income170 OtherIncome170Grp

Field	Value	IRS element (for citing)
Current Tax Year Minus1 Year	$116,870	CurrentTaxYearMinus1YearAmt
Current Tax Year	$58,024	CurrentTaxYearAmt
Total	$174,894	TotalAmt

Field	Value	IRS element (for citing)
Total Support	$243,520,497	TotalSupportAmt
Gross Receipts Rltd Activities	$67,239,847	GrossReceiptsRltdActivitiesAmt
Public Support CY170	0.70161	PublicSupportCY170Pct
Public Support PY170	0.61260	PublicSupportPY170Pct
Thirty Thr Pct Suprt Tests CY170	Yes (X)	ThirtyThrPctSuprtTestsCY170Ind

Schedule B IRS990ScheduleB

Contributor Information ContributorInformationGrp

Field	Value	IRS element (for citing)
Contributor	RESTRICTED	ContributorNum

Contributor Business Name ContributorBusinessName

Field	Value	IRS element (for citing)
Business Name Line1	RESTRICTED	BusinessNameLine1

Contributor US Address ContributorUSAddress

Field	Value	IRS element (for citing)
Address Line1	RESTRICTED	AddressLine1
Address Line2	RESTRICTED	AddressLine2
City	RESTRICTED	City
State	RESTRICTED	State
ZIP Code	RESTRICTED	ZIPCode

Field	Value	IRS element (for citing)
Total Contributions	RESTRICTED	TotalContributionsAmt

Schedule C IRS990ScheduleC

Field	Value	IRS element (for citing)
Total Grassroots Lobbying		TotalGrassrootsLobbyingGrp
Total Direct Lobbying		TotalDirectLobbyingGrp
Total Lobbying Expend		TotalLobbyingExpendGrp
Other Exempt Purpose Expend		OtherExemptPurposeExpendGrp
Total Exempt Purpose Expend		TotalExemptPurposeExpendGrp
Lobbying Nontaxable Amount		LobbyingNontaxableAmountGrp
Grassroots Nontaxable		GrassrootsNontaxableGrp
Tot Lbbyng Grassroot Mns Non Tx		TotLbbyngGrassrootMnsNonTxGrp
Tot Lbby Expend Mns Lbbyng Non Tx		TotLbbyExpendMnsLbbyngNonTxGrp
Volunteers	false	VolunteersInd
Paid Staff Or Management	Yes (true)	PaidStaffOrManagementInd
Media Advertisements	false	MediaAdvertisementsInd
Mailings Members	false	MailingsMembersInd
Publications Or Broadcast	false	PublicationsOrBroadcastInd
Grants Other Organizations	false	GrantsOtherOrganizationsInd
Direct Contact Legislators	false	DirectContactLegislatorsInd
Rallies Demonstrations	false	RalliesDemonstrationsInd
Other Activities	Yes (true)	OtherActivitiesInd
Other Activities	$92,490	OtherActivitiesAmt
Total Lobbying Expenditures	$92,490	TotalLobbyingExpendituresAmt
Not Described Section501c3	false	NotDescribedSection501c3Ind

Supplemental Information Detail SupplementalInformationDetail

Field	Value	IRS element (for citing)
Form And Line Reference	LOBBYING ACTIVITIES	FormAndLineReferenceDesc
Explanation	PART II-B, LINE 1I THROUGH ITS LEGISLATIVE CONSULTANT, NYGC ADVOCATED FOR GOVERNMENT FUNDS TO SUPPORT CURRENT OPERATIONS AND/OR EXPAND RESEARCH OPPORTUNITIES AT NYGC. THE ACTIVITIES INCLUDED, AND ARE NOT LIMITED TO, NEW YORK STATE AND NEW YORK CITY GOVERNMENTS. ADDITIONALLY, PORTIONS OF DUES NYGC PAID TO IRC SECTION 501(C)(6) ORGANIZATIONS WERE ATTRIBUTABLE TO LOBBYING. IN 2016, THE AMOUNT ATTRIBUTABLE TO LOBBYING WAS $2,490.	ExplanationTxt

Schedule D IRS990ScheduleD

Field	Value	IRS element (for citing)
Art Public Exhibition Amounts		ArtPublicExhibitionAmountsGrp
Held Works Art		HeldWorksArtGrp
CY Minus3 Yr Endwmt Fund		CYMinus3YrEndwmtFundGrp
CY Minus4 Yr Endwmt Fund		CYMinus4YrEndwmtFundGrp
Land		LandGrp
Buildings		BuildingsGrp

Leasehold Improvements LeaseholdImprovementsGrp

Field	Value	IRS element (for citing)
Other Cost Or Other Basis	$53,507,688	OtherCostOrOtherBasisAmt
Depreciation	$9,150,727	DepreciationAmt
Book Value	$44,356,961	BookValueAmt

Equipment EquipmentGrp

Field	Value	IRS element (for citing)
Other Cost Or Other Basis	$48,705,545	OtherCostOrOtherBasisAmt
Depreciation	$34,015,985	DepreciationAmt
Book Value	$14,689,560	BookValueAmt

Other Land Buildings OtherLandBuildingsGrp

Field	Value	IRS element (for citing)
Other Cost Or Other Basis	$1,503,695	OtherCostOrOtherBasisAmt
Depreciation	$632,813	DepreciationAmt
Book Value	$870,882	BookValueAmt

Field	Value	IRS element (for citing)
Total Book Value Land Buildings	$59,917,403	TotalBookValueLandBuildingsAmt

Other Assets Org OtherAssetsOrgGrp (2 entries)

DescDesc	Book ValueBookValueAmt
SECURITY DEPOSITS	$11,085,392
DEFERRED COMPENSATION	$238,130

Field	Value	IRS element (for citing)
Total Book Value Other Assets	$11,323,522	TotalBookValueOtherAssetsAmt
Federal Income Tax Liability	$0	FederalIncomeTaxLiabilityAmt

Other Liabilities Org OtherLiabilitiesOrgGrp (2 entries)

DescDesc	AmtAmt
ACCRUED INTEREST PAYABLE	$89,557
DEFERRED RENT	$27,001,101

Field	Value	IRS element (for citing)
Total Liability	$27,090,658	TotalLiabilityAmt
Footnote Text	Yes (X)	FootnoteTextInd
Total Rev Etc Audited Fincl Stmt	$132,356,996	TotalRevEtcAuditedFinclStmtAmt
Revenue Subtotal	$132,356,996	RevenueSubtotalAmt
Other Revenues Not Included	-$279,459	OtherRevenuesNotIncludedAmt
Revenue Not Reported Fincl Stmt	-$279,459	RevenueNotReportedFinclStmtAmt
Total Revenue Per Form990	$132,077,537	TotalRevenuePerForm990Amt
Tot Expns Etc Audited Fincl Stmt	$98,492,903	TotExpnsEtcAuditedFinclStmtAmt
Other Expenses Included	$279,459	OtherExpensesIncludedAmt
Expenses Not Reported	$279,459	ExpensesNotReportedAmt
Expenses Subtotal	$98,213,444	ExpensesSubtotalAmt
Total Expenses Per Form990	$98,213,444	TotalExpensesPerForm990Amt

Supplemental Information Detail SupplementalInformationDetail (2 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
INCOME TAXES	PART X, LINE 2 NYGC IS SUBJECT TO THE PROVISIONS OF FASB ASC SECTION 740-10-05, INCOME TAXES - OVERALL, RELATING TO ACCOUNTING AND REPORTING FOR UNCERTAINTY IN INCOME TAXES. NYGC RECOGNIZES THE EFFECT OF INCOME TAX POSITIONS ONLY IF THOSE POSITIONS ARE MORE LIKELY THAN NOT OF BEING SUSTAINED AND HAS DETERMINED IT DID NOT HAVE ANY EXPOSURE TO UNCERTAIN TAX POSITIONS DURING 2016 AND 2015.
REVENUE AND EXPENSE RECONCILIATION	PART XI, LINE 4B AND PART XII, LINE 2D ($279,459) RENTAL EXPENSES ALLOCABLE TO 990, PART VIII

Schedule G IRS990ScheduleG

Field	Value	IRS element (for citing)
In Person Solicitations	Yes (X)	InPersonSolicitationsInd
Agrmt Prof Fundraising Acty	Yes (true)	AgrmtProfFundraisingActyInd

Fundraiser Activity Info FundraiserActivityInfoGrp

Field	Value	IRS element (for citing)
Person	COMMUNITY COUNSELLING SERVICE	PersonNm
Activity	CAMPAIGN SERVICES	ActivityTxt
Fundraiser Control Of Funds	false	FundraiserControlOfFundsInd
Gross Receipts	$0	GrossReceiptsAmt
Retained By Contractor	$110,000	RetainedByContractorAmt
Net To Organization	-$110,000	NetToOrganizationAmt

Field	Value	IRS element (for citing)
Total Gross Receipts	$0	TotalGrossReceiptsAmt
Total Retained By Contractors	$110,000	TotalRetainedByContractorsAmt
Total Net To Organization	-$110,000	TotalNetToOrganizationAmt
Licensed States	CT	LicensedStatesCd
Licensed States	FL	LicensedStatesCd
Licensed States	NJ	LicensedStatesCd
Licensed States	NY	LicensedStatesCd
Licensed States	OK	LicensedStatesCd

Supplemental Information Detail SupplementalInformationDetail

Field	Value	IRS element (for citing)
Form And Line Reference	Schedule G, Part I, Line 2b	FormAndLineReferenceDesc
Explanation	Community Counselling Service's Address: 527 Madison Avenue 5th Floor New York, NY 10022 SCHEDULE G, PART I, LINE 2B, COLUMN (IV) NYGC UTILIZES THE SERVICES OF A FUNDRAISING ADVISOR TO CONSULT ON THE DEVELOPMENT ACTIVITIES OF THE ORGANIZATION; HOWEVER, DUE TO THE NATURE OF THESE ARRANGEMENTS, NYGC IS UNABLE TO REASONABLY DETERMINE THE GROSS RECEIPTS FROM THE FUNDRAISING ACTIVITIES WHICH ARE SOLELY ATTRIBUTABLE TO THIS ADVISOR.	ExplanationTxt

Schedule I IRS990ScheduleI

Field	Value	IRS element (for citing)
Grant Records Maintained	Yes (true)	GrantRecordsMaintainedInd

Recipient Table RecipientTable (6 entries)

Address Line1USAddress/AddressLine1Txt	Address Line2USAddress/AddressLine2Txt	CityUSAddress/CityNm	State AbbreviationUSAddress/StateAbbreviationCd	ZIPUSAddress/ZIPCd	Recipient EINRecipientEIN	IRC SectionIRCSectionDesc	Cash GrantCashGrantAmt	Purpose Of GrantPurposeOfGrantTxt
TRUSTEES OF COLUMBIA UNIV IN CITY OF NY
630 W 168TH ST	11TH FLOOR	NEW YORK	NY	10032	135598093	501(C)(3)	$103,656	RESEARCH SUBAWARD
COLD SPRING HARBOR LABORATORY
1 BUNGTOWN RD		COLD SPRING HARBOR	NY	11724	112013303	501(C)(3)	$151,302	RESEARCH SUBAWARD
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
ONE GUSTAVE L LEVY PL	BOX 1075	NEW YORK	NY	10029	136171197	501(C)(3)	$39,196	RESEARCH SUBAWARD
REGENTS OF THE UNIVERSITY OF CALIFORNIA-SF
1550 4TH STREET		SAN FRANCISCO	CA	94158	946036493	115 - CA	$17,689	RESEARCH SUBAWARD
REGENTS OF THE UNIVERSITY OF CALIFORNIA-LA
11000 KINROSS AVE		LOS ANGELES	CA	90095	956006143	115 - CA	$43,902	RESEARCH SUBAWARD
UNIVERSITY OF WASHINGTON
4333 BROOKLYN AVE NE		SEATTLE	WA	98195	916001537	115 - WA	$89,057	RESEARCH SUBAWARD

Field	Value	IRS element (for citing)
Total501c3 Org	6	Total501c3OrgCnt

Supplemental Information Detail SupplementalInformationDetail

Field	Value	IRS element (for citing)
Form And Line Reference	MONITORING USE OF GRANT FUNDS	FormAndLineReferenceDesc
Explanation	SCHEDULE I, PART I, LINE 2 NYGC MONITORS SUBRECIPIENTS' USE OF GRANT FUNDS IN MULTIPLE STAGES. IN THE PRE-AWARD PHASE, SUBRECIPIENTS ARE EVALUATED BY NYGC'S SPONSORED RESEARCH AND ACADEMIC/SCIENTIFIC DEPARTMENTS, WITH CONSIDERATION OF SUBRECIPIENT CAPABILITIES AND INFRASTRUCTURE, AS WELL AS THE APPROPRIATE CHECKS FOR SUSPENSION AND DEBARMENT. IN THE POST-AWARD PHASE, NYGC'S SPONSORED RESEARCH TEAM MONITORS PROGRAMMATIC PROGRESS (IN COORDINATION WITH ANY INTERNAL SCIENTIFIC PERSONNEL) IN A MANNER CONSISTENT WITH THE TERMS AND CONDITIONS OF THE AWARD. NYGC'S FINANCE/GRANTS ACCOUNTING DEPARTMENT REVIEWS ANY SUBRECIPIENT EXPENSES INVOICED TO NYGC FOR ALLOWABILITY WITH REGARD TO RELEVANT COST PRINCIPLES AND BUDGETARY RESTRICTIONS, AND PROVIDES SUBRECIPIENT INVOICES TO SPONSORED RESEARCH FOR THEIR REVIEW AND APPROVAL. ONCE THE SPONSORED RESEARCH AND FINANCE DEPARTMENTS HAVE APPROVED SUBRECIPIENT INVOICES, THE SUBRECIPIENT IS PAID. SUBAWARDS ELIGIBLE FOR FFATA REPORTING ARE RECORDED IN THE FSRS (THE FFATA SUBAWARD REPORTING SYSTEM) IN ACCORDANCE WITH THE FEDERAL REPORTING REQUIREMENTS FOR FIRST-TIER SUBAWARDS UNDER NYGC'S PRIME FEDERAL AWARDS.	ExplanationTxt

Schedule J IRS990ScheduleJ

Field	Value	IRS element (for citing)
First Class Or Charter Travel	Yes (X)	FirstClassOrCharterTravelInd
Idemnification Gross Up Pmts	Yes (X)	IdemnificationGrossUpPmtsInd
Housing Allowance Or Residence	Yes (X)	HousingAllowanceOrResidenceInd
Club Dues Or Fees	Yes (X)	ClubDuesOrFeesInd
Personal Services	Yes (X)	PersonalServicesInd
Written Policy Ref T And E Expnss	Yes (true)	WrittenPolicyRefTAndEExpnssInd
Substantiation Required	Yes (true)	SubstantiationRequiredInd
Compensation Committee	Yes (X)	CompensationCommitteeInd
Independent Consultant	Yes (X)	IndependentConsultantInd
Form990 Of Other Organizations	Yes (X)	Form990OfOtherOrganizationsInd
Compensation Survey	Yes (X)	CompensationSurveyInd
Board Or Committee Approval	Yes (X)	BoardOrCommitteeApprovalInd
Severance Payment	false	SeverancePaymentInd
Supplemental Nonqual Rtr Plan	Yes (true)	SupplementalNonqualRtrPlanInd
Equity Based Comp Arrngm	false	EquityBasedCompArrngmInd
Comp Based On Revenue Of Flng Org	false	CompBasedOnRevenueOfFlngOrgInd
Comp Bsd On Rev Related Orgs	false	CompBsdOnRevRelatedOrgsInd
Comp Bsd Net Earns Flng Org	false	CompBsdNetEarnsFlngOrgInd
Comp Bsd Net Earns Rltd Orgs	false	CompBsdNetEarnsRltdOrgsInd
Any Non Fixed Payments	false	AnyNonFixedPaymentsInd
Initial Contract Exception	Yes (true)	InitialContractExceptionInd
Rebuttable Presumption Proc	Yes (true)	RebuttablePresumptionProcInd

Rltd Org Officer Trst Key Empl RltdOrgOfficerTrstKeyEmplGrp (13 entries)

TitleTitleTxt	Base Compensation Filing OrgBaseCompensationFilingOrgAmt	Compensation Based On Rltd OrgsCompensationBasedOnRltdOrgsAmt	Bonus Filing OrganizationBonusFilingOrganizationAmount	Bonus Related OrganizationsBonusRelatedOrganizationsAmt	Other Compensation Filing OrgOtherCompensationFilingOrgAmt	Other Compensation Rltd OrgsOtherCompensationRltdOrgsAmt	Deferred Compensation Flng OrgDeferredCompensationFlngOrgAmt	Deferred Comp Rltd OrgsDeferredCompRltdOrgsAmt	Nontaxable Benefits Filing OrgNontaxableBenefitsFilingOrgAmt	Nontaxable Benefits Rltd OrgsNontaxableBenefitsRltdOrgsAmt	Total Compensation Filing OrgTotalCompensationFilingOrgAmt	Total Compensation Rltd OrgsTotalCompensationRltdOrgsAmt	Comp Report Prior990 Filing OrgCompReportPrior990FilingOrgAmt	Comp Report Prior990 Rltd OrgsCompReportPrior990RltdOrgsAmt
ROBERT B DARNELL MD PHD
FOUNDING DIR&CEO-THRU 12/31/16	$324,089	$0	$0	$0	$16,873	$0	$0	$0	$0	$0	$340,962	$0	$0	$0
CHERYL A MOORE
PRESIDENT & COO - EFF. 1/11/16	$877,358	$0	$75,000	$0	$322,942	$0	$196,583	$0	$3,107	$0	$1,474,990	$0	$0	$0
CAROL ASHE
CHIEF BUSINESS OFFICER	$396,305	$0	$41,600	$0	$18,544	$0	$13,250	$0	$117	$0	$469,816	$0	$0	$0
HAROLD SWERDLOW PHD
VICE PRESIDENT OF SEQUENCING	$405,211	$0	$0	$0	$0	$0	$13,250	$0	$26,068	$0	$444,529	$0	$0	$0
KATHLEEN MCGOVERN KEARNS
VICE PRESIDENT, DEV'T & COMM	$385,408	$0	$0	$0	$10,007	$0	$10,000	$0	$18,979	$0	$424,394	$0	$0	$0
TOBY BLOOM PHD
DEPUTY SCIENTIFIC DIR., INFO.	$349,086	$0	$0	$0	$0	$0	$13,250	$0	$21,479	$0	$383,815	$0	$0	$0
MATTHEW J PELO
VP, FINANCIAL STRATEGY & OPS	$311,307	$0	$0	$0	$0	$0	$12,520	$0	$8,206	$0	$332,033	$0	$0	$0
ELIZABETH O'BRIEN
VICE PRESIDENT & GEN. COUNSEL	$309,685	$0		$0	$75,147	$0	$13,250	$0	$24,737	$0	$422,819	$0	$0	$0
SHAILAJA GARGEYA
SENIOR DIR. SOFTWARE ENGINEER	$286,274	$0	$0	$0	$0	$0	$13,250	$0	$11,691	$0	$311,215	$0	$0	$0
LISA ESCUDERO
VP, HUMAN RESOURCES	$244,910	$0	$0	$0	$0	$0	$9,375	$0	$21,614	$0	$275,899	$0	$0	$0
DAYNA M OSCHWALD
SNR. DIR, INFO. PGM MGMT	$223,086	$0	$2,500	$0	$0	$0	$7,652	$0	$17,346	$0	$250,584	$0	$0	$0
JOSEPH PICKRELL
CORE MEMBER, ASST INVESTIGATOR	$157,141	$0	$0	$0	$42,000	$0	$10,237	$0	$20,951	$0	$230,329	$0	$0	$0
CHRIS DUIGNAN
VP, FINANCE	$299,329	$0	$0	$0	$0	$0	$12,480	$0	$30,537	$0	$342,346	$0	$0	$0

Supplemental Information Detail SupplementalInformationDetail (4 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
SCHEDULE J, PART I, LINE 1	FIRST-CLASS OR CHARTER TRAVEL In 2016, on a single occasion, the President and COO traveled one-level above economy class on a business-related flight. Because the travel was for business, it was not treated as taxable to the employee. TAX INDEMNIFICATION AND GROSS-UP PAYMENTS NYGC PROVIDED RELOCATION SERVICES FOR THE FOLLOWING EMPLOYEEs HIRED FROM OUTSIDE NEW YORK CITY: President and COO, Vice President and General Counsel. THE VALUE OF THESE RELOCATION SERVICES WAS TREATED AS COMPENSATION TO THE EMPLOYEE FOR WHICH NYGC MADE GROSS-UP PAYMENTS TO ALLEVIATE THE TAX BURDEN ON THE EMPLOYEE. NYGC also provided tuition assistance for a family member to the Vice President and General Counsel. THE VALUE OF this assistance WAS TREATED AS COMPENSATION TO THE EMPLOYEE FOR WHICH NYGC MADE GROSS-UP PAYMENTS TO ALLEVIATE THE TAX BURDEN ON THE EMPLOYEE. HOUSING ALLOWANCE OR RESIDENCE FOR PERSONAL USE NYGC provided a housing allowance for the following employees listed in Form 990, Part VII, Section A, Line 1a: Cheryl Moore, Joseph Pickrell. The value of this assistance WAS TREATED AS compensation to the employee. NYGC selectively offers housing allowances to employees, principally as a recruiting tool for new faculty and postdoctoral fellows. Subsidized housing or housing allowances are commonly offered by peer academic institutions in New York City to help faculty and other researchers defray the high cost of housing. HEALTH OR SOCIAL CLUB DUES OR INITIATION FEES NYGC paid health club dues for its former Founding Scientific Director and CEO. The value of this assistance was treated as compensation to the employee. PERSONAL SERVICES NYGC provided certain meals and transportation services to the former Founding Scientific Director and CEO. The value of which was treated as compensation to the employee.
EXECUTIVE COMPENSATION	SCHEDULE J, PART I, LINE 3 An ad-hoc Executive Compensation Committee of the board was responsible for establishing the President and COOs compensation package and terms of her employment contract. Her compensation was determined through a review of Form 990 returns and compensation information for top management officials at similarly situated organizations obtained through the recruiting process. Consideration also was given to her then-current compensation. ON RECOMMENDATION OF THE ad-hoc Executive Compensation Committee, the Board of Directors approved her compensation. In late 2016, NYGC hired an independent compensation consultant to review the compensation paid to senior management; results of this review were provided TO THE BOARD'S STANDING EXECUTIVE COMPENSATION COMMITTEE IN EARLY 2017. THE review showed that the compensation paid to all members of senior management was reasonable.
SUPPLEMENTAL NONQUALIFIED RETIREMENT PLAN	Schedule J, Part I, Line 4b NYGC has a deferred compensation plan for the President and COO. $183,333 was deferred in 2016.
INITIAL CONTRACT EXCEPTION	Schedule J, Part I, Lines 8 & 9 All amounts reported, paid, or accrued for the President and COO were fixed and subject to the initial contract exception. Notwithstanding the initial contract exception, NYGC gathered independent external salary information TO ESTABLISH THAT the President and COO'S COMPENSATION WAS REASONABLE (NOTED IN SCHEDULE J, PART I, LINE 3).

Schedule O IRS990ScheduleO

Supplemental Information Detail SupplementalInformationDetail (8 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
THE ORGANIZATIONS MISSION	FORM 990, PART I, LINE 1 & PART III, LINE 1: NYGC is organized and operated as an independent, non-profit corporation, dedicated to state-of-the-art, world class genome sequencing, bioinformatics and research, whose members include leading academic, medical and research institutions. NYGC has the following key objectives: (i) Creating an intellectually vibrant collaboration amongst the academic and scientific community in New York City; (ii) Recruiting world class scientific leadership to direct the scientific development of the Corporation; (iii) Obtaining commitments from the Institutional Founding Members, other academic, research and medical institutions and the biotechnology/pharmaceutical industry to affiliate with and use services provided by the Corporation; (iv) Providing sequencing and bioinformatics services to the academic and scientific communities, including the Institutional Founding Members; (v) Developing advanced bioinformatics capabilities based upon the research and sequencing activities conducted at the Corporations facilities; (vi) Advancing the development of new treatments, therapies and therapeutics to treat human disease; (vii) Providing training to the academic, research and technology communities; and (viii) Conducting activities ancillary to these objectives.
PROGRAM SERVICE ACCOMPLISHMENTS	FORM 990, PART III, LINE 2, LINE 4A, LINE 4B, LINE 4C The New York Genome Center (NYGC) is an independent, nonprofit academic research institution with the mission of advancing clinical care through transformative genomic research. Collaborating with premier academic, medical and industry leaders across the globe, the NYGCs goal is to translate genomic research into the development of new treatments, therapies and therapeutics against human disease. NYGC and its member organizations and partners are united in this unprecedented collaboration of technology, science and medicine, designed to harness the power of innovation and discoveries to advance genomic services. Their shared objective is the acceleration of medical genomics and precision medicine to benefit patients around the world. What makes the NYGC unique and a strong collaborative partner are our innovation, research and quality. 2016 was an exciting year of progress and transition at the NYGC. We made strong strides to further our mission, reaching important new milestones. The NYGC sequenced 20,000 whole genome samples, completed 1,000 projects, and collaborated with 260 investigators from 89 institutions worldwide. We were pleased to welcome Princeton University as our newest Institutional Associate Member. This new partnership paves the way for new collaborations and innovation between researchers at Princeton University, its Lewis-Sigler Institute, the NYGC and our other member institutions. Advancing Genomics Our scientists have made impactful new discoveries, developed open source novel methods used by the scientific community, and produced exceptional quality publications in many peer-reviewed scientific journals. Working together with our member institutions, our researchers were the recipients of grants totaling more than $20 million in 2016. The NYGC was awarded $40 million, over four years, in January 2016 from the National Human Genome Research Institute (NHGRI) of the National Institutes of Health (NIH), to create a Center for Common Disease Genomics (CCDG) and establish a collaborative, large-scale genome sequencing program. The NHGRIs CCDG program funds only four centers across the country. NYGCs CCDG uses whole genome sequencing to explore genomic contributions to common diseases. In 2016, NYGCs CCDG focused primarily on studying autism. NYGC entered into a collaboration agreement with IBM, our Founding Technology Member, to build a comprehensive and open repository of genetic data to accelerate cancer research. This joint initiative between the NYGC and IBM, called the Cancer Genomics Alliance study, was recognized and highlighted at the 2016 White House Precision Medicine Initiative Summit. NYGC scientists sequenced the DNA and RNA from 200 cancer patients being treated at our member institutions. NYGC is housing the contributed data and training IBM Watsons cognitive computing capacities for genomic analysis. Genetic information and clinical data from these patients were shared with Watson along with massive amounts of medical evidence to help identify existing drugs that may be candidates to potentially target patients cancer-causing mutations. All clinically actionable results were shared with treating physicians. Research and Faculty Since its inception, the NYGC has attracted world-class scientists whose genomic expertise including single cell genomics, genome engineering, population and evolutionary genomics, technology and methods development, statistics, computational biology and bioengineering bring a multidisciplinary and in-depth approach to the evolving field of genomics. In 2016, we recruited two distinguished researchers, Drs. Neville Sanjana and Simon Tavar, to our faculty, broadening our research focus and capabilities. Neville Sanjana, PhD, joined the NYGC as a Core Member and Assistant Investigator. Dr. Sanjanas scientific expertise includes genome engineering, functional genomic screening using programmable nucleases, autism genetics and synaptic pathophysiology. He holds a joint appointment at New York University as an Assistant Professor in the Department of Biology and the Center for Genomics and Systems Biology and an associate faculty appointment with the Institute for Systems Genetics at New York University Langone Medical Center. Previously at the Broad Institute of Harvard and the Massachusetts Institute of Technology and in the Departments of Brain and Cognitive Sciences and Bioengineering at the Massachusetts Institute of Technology, Dr. Sanjana was a postdoctoral scientist in the laboratory of Dr. Feng Zhang. Dr. Sanjana received his PhD in Brain and Cognitive Sciences from the Massachusetts Institute of Technology and completed his undergraduate education at Stanford University. He uses the genome-engineering tools in a variety of contexts to understand how genetic variants affect human health and disease. Simon Tavar, PhD, joined the NYGC as a Senior Researcher while continuing his appointments as the Director of the Cancer Research UK Cambridge Institute and Professor in the Departments of Oncology and Applied Mathematics and Theoretical Physics at the University of Cambridge. Dr. Tavar is widely recognized as one of the worlds leading experts in statistics and probability in computational biology. His research interests include statistical genetics, evolutionary approaches to cancer and stochastic computation. Dr. Tavar received his BSc degree, MSc degree and PhD in probability and statistics from the University of Sheffield, UK. He was elected a Fellow of the Academy of Medical Sciences in 2009 and named a Fellow of the Royal Society in 2011. NYGCs faculty support the scientific vision of the NYGC through the advancement of genomic medicine. Faculty members have joint appointments at our Institutional Founding Members to strengthen our research capabilities, advance academic leadership, and enhance the ability to help solve human diseases. In 2016, NYGCs faculty were awarded several prestigious grants, including the NIHs New Innovator Award, a grant from the National Breast Cancer Coalition, and a Stand Up to Cancer Innovative Research Grant. Rahul Satija, PhD, received a New Innovator Award from the National Institutes of Health to fund research focusing on how the interaction between molecular and environmental factors governs cell behavior. Yaniv Erlich, PhD, and Joseph Pickrell, PhD, were awarded a grant from the National Breast Cancer Coalition to expand the services of DNA.Land, the nonprofit web-based platform they created that houses genomes from more than 40,000 people, for a targeted collection of data of breast cancer patients. Dan Landau, MD, PhD, was the recipient of a Stand Up to Cancer Innovative Research Grant for a project with Weill Cornell Medicine, focused on a new mathematical approach to design combination therapies for chronic lymphocytic leukemia. Our Center for Genomics of Neurodegenerative Diseases ALS Consortium, led by Hemali Phatnani, PhD, was joined by two new members, The Jackson Laboratory and the University of California, Irvine. In 2016, the Consortium included 15 leading institutions in the United States and abroad. Scientists and clinicians work collaboratively to apply state-of-the-art clinical and functional genomics together with bioinformatics to study ALS disease mechanisms and better understand how mutations underlying ALS cause disease. The target of this global multidisciplinary effort is whole genome sequencing and analysis of 3,200 clinically well-annotated ALS samples within the next three years to enhance early diagnosis and effective drug discovery. To advance collaborative efforts on cancer genomics, Nobel Laureate Harold Varmus, MD, Senior Associate Core Member, NYGC, and Lewis Thomas University Professor of Medicine, Weill Cornell Medicine, established the New York Cancer Genomics Research Network. Dr. Varmus convenes monthly meetings at the NYGC with leading cancer researchers and clinicians from our Institutional Founding Members and other key academic institutions around the world. The objective of this multidisciplinary approach is to help set critical priorities in translating genomic science into more effective treatment options for all cancer patients in New York and beyond. Marcin Imielinski, MD, PhD, discovered a new class of mutations in cancer that may represent a novel class of driver in liver, lung, thyroid and stomach cancer, and his findings were subsequently published in Cell. Neville Sanjana, PhD, utilized CRISPR, an advanced gene-editing technique, to analyze non-coding regions of the human genome that drive drug-resistant cancer. His study, which may offer new treatment options for patients with melanoma and other cancers, was published in Science and featured in an article in TIME.
Joseph Pickrell, PhD, and Yaniv Erlich, PhD, completed several	breakthrough genome-wide association studies in 2016. One study discovered multi-tasking genes that influence a wide variety of human traits and conditions, identifying some unexpected connections between diseases. This research could provide a powerful new tool for scientists to identify shared causal relationships between diseases and better understand how diseases interrelate. In another study, Drs. Pickrell and Erlich deployed advanced data analytics and genome-wide association by proxy, using the DNA of patients families to map risk factors. They uncovered 17 new disease-causing mutations for Alzheimers disease, cardiac disease and diabetes. Both studies were published in Nature Genetics. In 2016, researchers at the NYGC helped contribute to advancements in the field of genomics through their translational research on a wide range of diseases. Their findings were published in more than 50 high-impact scientific journals. Bioinformatics and Data Management NYGCs Bioinformatics scientists play a leadership role in the complex analysis of multiple datasets, including integrating and harmonizing clinical and genomic data. In 2016, our Bioinformatics team conducted an array of investigations, including research on renal cell carcinoma, autism and breast cancer. They also developed and will shortly launch the MetroNome database, a web application that allows researchers to explore data visually, with the goal of correlating genotypes with phenotypes. The system accepts genomic sequencing and clinical data from any research project. Participating researchers can explore their data in an interactive, visual interface and organize data along many dimensions MetroNome enables investigators to search for genomic differences across large populations, investigate the effects of genomic variants and relate them to phenotypic conditions. The Bioinformatics teams research in 2016 has resulted in more than a dozen publications, in journals such as Nature, The American Journal of Human Genetics and The Journal of Clinical Investigation. We also strengthened collaborative research projects with our Institutional Founding Members in 2016, and were jointly awarded a National Cancer Institute grant with Weill Cornell Medicine for a specialized genomic data center, with Michael Zody, PhD, Senior Director, Computational Biology, as the co-principal investigator at the NYGC. Technology Innovation Today, there are numerous exciting clinical uses for genomic information, yet such information has to be generated and interpreted in a timely, scalable, and high-quality fashion in order to speed and improve the delivery of results to researchers and clinicians. The NYGC Technology Innovation Lab is a creative, multidisciplinary hub where our scientists are developing cutting-edge technologies to advance genomics research and clinical applications, particularly for cancer researchers and clinicians. The Technology Innovation Lab is dedicated to generating new technologies, protocol development, equipment evaluation, and informatics tool development/integration. Our scientists are developing various novel technologies to speed up, reduce costs and decrease the handling of next-generation library preparation reactions. In 2016, we developed a whole genome bisulfite sequencing library prep compatible with HiSeq X, reducing the cost of the whole genome bisulfite sequencing by two-thirds, and cutting the turnaround time in half, making this important technology accessible to researchers worldwide. Clinical Sequencing NYGCs Clinical Sequencing Laboratory offers tests that are intended to further our mission of translating genomic research into clinical solutions for serious disease. The Laboratory received New York State Clinical Laboratory Evaluation Program (CLEP) certification from the New York State (NYS) Department of Health (DOH) in 2014. Its first two genomics laboratory-developed tests, a constitutional whole exome sequencing test for undiagnosed disease and a targeted variant test (Sanger-sequencing based assay to confirm the mutations identified by research next-generation sequencing for constitutional diseases), received CLEP approval from the NYS DOH in 2015. In 2016, the NYGC received conditional approval from the NYS DOH for constitutional whole genome sequencing for undiagnosed disease, as well as those patients who are seeking predispositional genetic testing. Applications for approval of additional tests are pending with the NYS DOH. Education As part of the NYGCs educational mission, we hosted many scientific meetings, workshops, conferences and lectures in 2016. We held Evening Talks, our lecture series for the general public on advances in genomic science, sponsored by The New York City Community Trust Pyewacket Fund. We hosted Five Points lectures for the scientific community, featuring leading researchers from around the country and abroad. In addition, the NYGC held well-attended workshops for the medical community on single cell genomics, epigenomics, sequencing informatics and ancestry. In September 2016 the NYGC hosted the first DNA.Land User Group Meeting. This unique "family reunion" was attended by more than 100 people and attracted media coverage on Fox 5 News. Also in September 2016, the NYGC hosted its first Sequencing Informatics Workshop, which was organized by Michael Zody, PhD. Colleagues at our Institutional Founding Members, graduate students, postdocs, faculty and core and research laboratory staff learned the basics of sequence data alignment, data analysis and identifying somatic variations in cancer samples. Participants also learned how to read and understand common file formats and analyze RNA-seq data for expression and differential expression. In October 2016, the NYGC hosted its inaugural Single Cell Genomics Day: A Practical Workshop to provide researchers a basic overview of single cell sequencing. The event, organized by the NYGCs Rahul Satija, PhD, attracted 200 attendees from 30 academic and commercial institutions. The program focused on technology development, molecular protocols and computational analysis. In May 2016, the NYGC hosted our second annual New York Epigenomics Symposium. This day-long event, organized by NYGCs Will Liao, PhD, was attended by more than 160 people. It included sessions that explored recent discoveries, ongoing work and novel methods in the field of epigenomics.epigenomics. epigenomics.epigenomics.
Significant Changes to governing documents	Form 990, Part VI, Line 4: IN 2016, NYGC AMENDED ITS BYLAWS TO MODIFY THE BOARD'S COMMITTEE STRUCTURE, WHICH NOW INCLUDES THE FOLLOWING STANDING COMMITTEES OF THE BOARD: EXECUTIVE COMMITTEE, AUDIT COMMITTEE, COMPENSATION COMMITTEE, DEVELOPMENT COMMITTEE, FINANCE COMMITTEE, AND NOMINATING AND GOVERNANCE COMMITTEE. NOTE THAT PRIOR TO 2016, NYGC'S COMMITTEES INCLUDED A FINANCE AND AUDIT COMMITTEE, AND A COMPENSATION COMMITTEE. ORGANIZATION MEMBERS FORM 990, PART VI, SECTION A, LINE 6: As of December 31, 2016, the Center has a total of 18 members, consisting of 12 institutional founding members, five associate members, and one founding technology member. THE INSTITUTIONAL FOUNDING MEMBERS ARE THE FOLLOWING RECOGNIZED ACADEMIC, MEDICAL AND RESEARCH INSTITUTIONS: (1) COLD SPRING HARBOR LABORATORY, (2) CORNELL UNIVERSITY/WEILL CORNELL MEDICAL COLLEGE, (3) THE JACKSON LABORATORY, (4) MEMORIAL SLOAN-KETTERING CANCER CENTER, (5) ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, (6) NEW YORK-PRESBYTERIAN HOSPITAL, (7) NEW YORK UNIVERSITY, (8) NORTHWELL HEALTH, (9) THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, ON BEHALF OF STONY BROOK UNIVERSITY, (10) THE ROCKEFELLER UNIVERSITY, (11) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, AND (12) ALBERT EINSTEIN COLLEGE OF MEDICINE ASSOCIATE MEMBERS: (1) AMERICAN MUSEUM OF NATURAL HISTORY (2) HOSPITAL FOR SPECIAL SURGERY (3) THE NEW YORK STEM CELL FOUNDATION (4) ROSWELL PARK CANCER INSTITUTE (5) PRINCETON UNIVERSITY *TECHNOLOGY MEMBER: (1) INTERNATIONAL BUSINESS MACHINES (IBM) (1) INTERNATIONAL BUSINESS MACHINES (IBM) ORGANIZATION MEMBERS - DECISION MAKING FORM 990, PART VI, SECTION A, LINE 7A & 7B: EACH INSTITUTIONAL FOUNDING MEMBER APPOINTS ONE REPRESENTATIVE TO SERVE ON THE BOARD OF DIRECTORS. The Board of Directors also includes THE SCIENTIFIC DIRECTOR and other designated directors or individuals appointed by the board. DECISIONS REQUIRING BOARD APPROVAL INCLUDE the admission of new members, CHANGEs TO THE MISSION, CERTIFICATE OF INCORPORATION, AND BYLAWS, appointment or removal of the Chairperson of the Board and the Scientific Director, adoption of certain policies and procedures, etc. THE BOARD ALSO REVIEWS AND APPROVES THE ANNUAL OPERATING BUDGET. MANAGEMENT HAS THE ABILITY TO ENTER INTO BUSINESS ARRANGEMENTS AND CONTRACTS, INCLUDING FINANCING ARRANGEMENTS.
FORM 990 REVIEW	FORM 990, PART VI, SECTION B, LINE 11: THE FORM 990 IS PREPARED BY AN INDEPENDENT PUBLIC ACCOUNTING FIRM, UTILIZING INFORMATION PROVIDED BY MANAGEMENT. UPON RECEIPT OF THE DRAFT 990, MANAGEMENT, including the VP OF FINANCE, GENERAL COUNSEL, AND PRESIDENT, REVIEWS THE 990. PRIOR TO FILING, MANAGEMENT PRESENTS THE 990 TO THE AUDIT COMMITTEE FOR REVIEW AND COMMENT. ALSO PRIOR TO FILING, MANAGEMENT WILL PROVIDE THE 990 TO THE BOARD OF DIRECTORS.
CONFLICT OF INTEREST POLICY & REVIEW	FORM 990, PART VI, SECTION B, LINE 12C: NYGC REQUIRES ALL INTERESTED PERSONS (DEFINED AS BOARD MEMBERS, PRINCIPAL OFFICERS, OR MEMBERS OF A COMMITTEE IN WHICH THE BOARD HAS DELEGATED POWERS) TO DISCLOSE CONFLICTS OF INTEREST AS REQUIRED BY THE CONFLICT OF INTEREST POLICY. NYGC FOLLOWS A PROCEDURE FOR OBTAINING SUCH DISCLOSURES ANNUALLY. ANY POTENTIAL CONFLICTS OF INTEREST MUST BE REVIEWED BY THE BOARD. IF AN INTERESTED PERSON HAS A POTENTIAL CONFLICT OF INTEREST, HE OR SHE MAY MAKE A PRESENTATION AT THE BOARD OR COMMITTEE MEETING, BUT AFTER SUCH PRESENTATION, HE/SHE SHALL LEAVE THE MEETING DURING THE DISCUSSION OF, AND THE VOTE ON, THE TRANSACTION OR ARRANGEMENT THAT CREATES THE POTENTIAL CONFLICT OF INTEREST.
COMPENSATION REVIEW AND APPROVAL	FORM 990, PART VI, SECTION B, LINE 15: For the organizations top management official, please refer to Schedule J narratives for process of determining compensation. For Robert Darnell, in 2012, the Board of Directors approved his consulting fee; in 2016, the Executive Compensation Committee approved an increase to his consulting fee. For all other officers and key employees, there were no merit increases or salary changes in 2016. NOTE THE COMPENSATION PAID TO NYGC'S SENIOR LEADERSHIP team WAS REVIEWED AND APPROVED IN THE PRIOR YEAR BY THE AD-HOC EXECUTIVE COMPENSATION COMMITTEE. THE MEMBERS OF THe COMMITTEE WERE INDEPENDENT MEMBERS OF NYGC'S BOARD OF DIRECTORS. THE COMMITTEE OBTAINED COMPARABILITY DATA FROM AN INDEPENDENT THIRD-PARTY PROVIDER (RADFORD SURVEYS) FOR ALL OF THE SENIOR LEADERSHIP POSITIONS, AND RELIED ON THIS INFORMATION IN DETERMINING THE REASONABLENESS OF COMPENSATION. THE COMMITTEE DOCUMENTED ITS DECISIONS REGARDING COMPENSATION IN WRITING. Further, NYGC hired an independent compensation consultant IN 2016 to review senior managements compensation; results of this review were provided to the Executive Compensation Committee in early 2017.
DOCUMENT DISCLOSURE	FORM 990, PART VI, SECTION C, LINE 19: NYGC'S GOVERNING DOCUMENTS, CONFLICT OF INTEREST POLICY, AND FINANCIAL STATEMENTS ARE AVAILABLE UPON REQUEST. LOANS PAYABLE FORM 990, PART X, LINE 24, LINE 26 In 2011, eleven institutional founding members loaned $2.5 million each to NYGC, totaling $27.5 million. In 2013, a twelfth member joined the institutional founding members, loaning an additional $2.5 million to NYGC. Each of the twelve institutional founding members received a subordinated promissory note. Principal and interest were payable upon maturity. In March 2016, the 12 institutional founding members demonstrated their support for NYGC by forgiving the $30 million dollar loan and approximately $4 million of accrued interest and converted the total amount to a contribution to NYGC.