THE SILVERSTEIN FOUNDATION FOR GBA RESEARCH: Form 990, tax year 2019

View the entire original 990 at ProPublica ↗

Organization
THE SILVERSTEIN FOUNDATION FOR GBA RESEARCH (EIN 82-0656623)
Tax period
2019-01-01 to 2019-12-31
Filed
2020-09-18
IRS object ID
202002629349300910
Schema version
2019v5.1
Source
Download XML · Original 990 at ProPublica

Every field in the e-filed return. Faint text is the IRS element name, for citing.

Return header ReturnHeader

FieldValueIRS element (for citing)
Return2020-09-18T10:45:50-05:00ReturnTs
Tax Period End2019-12-31TaxPeriodEndDt

Preparer Firm PreparerFirmGrp

Preparer Firm Name PreparerFirmName

FieldValueIRS element (for citing)
Business Name Line1KPMG LLPBusinessNameLine1Txt

Preparer US Address PreparerUSAddress

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Address Line1345 Park AveAddressLine1Txt
CityNew YorkCityNm
State AbbreviationNYStateAbbreviationCd
ZIP101540102ZIPCd
FieldValueIRS element (for citing)
Return Type990ReturnTypeCd
Tax Period Begin2019-01-01TaxPeriodBeginDt

Filer Filer

FieldValueIRS element (for citing)
EIN820656623EIN

Business Name BusinessName

FieldValueIRS element (for citing)
Business Name Line1The Silverstein Foundation for Parkinson'sBusinessNameLine1Txt
Business Name Line2with GBABusinessNameLine2Txt
FieldValueIRS element (for citing)
In Care Of% JONATHAN T SILVERSTEINInCareOfNm
Business Name ControlSILVBusinessNameControlTxt
Phone9175198108PhoneNum

US Address USAddress

FieldValueIRS element (for citing)
Address Line1PO BOX 237137AddressLine1Txt
CityNEW YORKCityNm
State AbbreviationNYStateAbbreviationCd
ZIP10023ZIPCd

Business Officer BusinessOfficerGrp

FieldValueIRS element (for citing)
PersonNATALIE SILVERSTEINPersonNm
Person Titlevice pres/treasurerPersonTitleTxt
Phone9175198108PhoneNum
Signature2020-09-17SignatureDt
Discuss With Paid PreparerYes (true)DiscussWithPaidPreparerInd

Preparer Person PreparerPersonGrp

FieldValueIRS element (for citing)
Preparer PersonDAVID M HIGHFILLPreparerPersonNm
PTINP01517891PTIN
Phone2127589700PhoneNum
Preparation2020-09-18PreparationDt

Filing Security Information FilingSecurityInformation

IP Address IPAddress

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I Pv4 Address199.207.253.101IPv4AddressTxt
FieldValueIRS element (for citing)
Federal Original Submission Id13407320202625000010FederalOriginalSubmissionId
Federal Original Submission Id2020-09-18FederalOriginalSubmissionIdDt
Filing License TypePFilingLicenseTypeCd
At Submission Creation Device IdAAE0097B1BC93C87019AE0794913F3C1E354ED8CAtSubmissionCreationDeviceId
At Submission Filing Device IdAAE0097B1BC93C87019AE0794913F3C1E354ED8CAtSubmissionFilingDeviceId
FieldValueIRS element (for citing)
Tax2019TaxYr
Build TS2021-01-29 14:40:06ZBuildTS

Form 990 IRS990

FieldValueIRS element (for citing)
Principal OfficerJONATHAN SILVERSTEINPrincipalOfficerNm

US Address USAddress

FieldValueIRS element (for citing)
Address Line1PO BOX 237137AddressLine1Txt
CityNEW YORKCityNm
State AbbreviationNYStateAbbreviationCd
ZIP10023ZIPCd
FieldValueIRS element (for citing)
Gross Receipts$440,986GrossReceiptsAmt
Group Return For AffiliatesfalseGroupReturnForAffiliatesInd
Organization501c3Yes (X)Organization501c3Ind
Website AddressWWW.silversteinfoundation.orgWebsiteAddressTxt
Type Of Organization CorpYes (X)TypeOfOrganizationCorpInd
Formation2017FormationYr
Legal Domicile StateNYLegalDomicileStateCd
Activity Or MissionTO RAISE AWARENESS AROUND PARKINSON'S DISEASE ASSOCIATED WITH GBA MUTATIONS AND RELEVANT CLINICAL TRIALS FOR MUTATION CARRIERS. SEE ALSO PART III AND SCHEDULE O.ActivityOrMissionDesc
Voting Members Governing Body3VotingMembersGoverningBodyCnt
Voting Members Independent3VotingMembersIndependentCnt
Total Employee0TotalEmployeeCnt
Total Volunteers3TotalVolunteersCnt
Total Gross UBI$0TotalGrossUBIAmt
Net Unrelated Bus Txbl Incm$0NetUnrelatedBusTxblIncmAmt
PY Contributions Grants$599,990PYContributionsGrantsAmt
CY Contributions Grants$379,686CYContributionsGrantsAmt
PY Program Service Revenue$0PYProgramServiceRevenueAmt
CY Program Service Revenue$0CYProgramServiceRevenueAmt
PY Investment Income$61,051PYInvestmentIncomeAmt
CY Investment Income$51,242CYInvestmentIncomeAmt
PY Other Revenue$0PYOtherRevenueAmt
CY Other Revenue$0CYOtherRevenueAmt
PY Total Revenue$661,041PYTotalRevenueAmt
CY Total Revenue$430,928CYTotalRevenueAmt
PY Grants And Similar Paid$2,651,807PYGrantsAndSimilarPaidAmt
CY Grants And Similar Paid$848,201CYGrantsAndSimilarPaidAmt
PY Benefits Paid To Members$0PYBenefitsPaidToMembersAmt
CY Benefits Paid To Members$0CYBenefitsPaidToMembersAmt
PY Salaries Comp Emp Bnft Paid$0PYSalariesCompEmpBnftPaidAmt
CY Salaries Comp Emp Bnft Paid$0CYSalariesCompEmpBnftPaidAmt
PY Total Prof Fndrsng Expns$0PYTotalProfFndrsngExpnsAmt
CY Total Prof Fndrsng Expns$0CYTotalProfFndrsngExpnsAmt
CY Total Fundraising Expense$0CYTotalFundraisingExpenseAmt
PY Other Expenses$108,591PYOtherExpensesAmt
CY Other Expenses$57,099CYOtherExpensesAmt
PY Total Expenses$2,760,398PYTotalExpensesAmt
CY Total Expenses$905,300CYTotalExpensesAmt
PY Revenues Less Expenses-$2,099,357PYRevenuesLessExpensesAmt
CY Revenues Less Expenses-$474,372CYRevenuesLessExpensesAmt
Total Assets BOY$3,393,950TotalAssetsBOYAmt
Total Assets EOY$3,351,322TotalAssetsEOYAmt
Total Liabilities BOY$155,000TotalLiabilitiesBOYAmt
Total Liabilities EOY$16,925TotalLiabilitiesEOYAmt
Net Assets Or Fund Balances BOY$3,238,950NetAssetsOrFundBalancesBOYAmt
Net Assets Or Fund Balances EOY$3,334,397NetAssetsOrFundBalancesEOYAmt
Info In Schedule O Part IIIYes (X)InfoInScheduleOPartIIIInd
MissionTHE SILVERSTEIN FOUNDATION FOR PARKINSON'S WITH GBA RESEARCH RAISES AWARENESS AROUND PARKINSON'S DISEASE ASSOCIATED WITH GBA MUTATIONS. SEE SCHEDULE O FOR MORE INFORMATION.MissionDesc
Significant New Program SrvcfalseSignificantNewProgramSrvcInd
Significant ChangefalseSignificantChangeInd
Expense$848,201ExpenseAmt
Grant$848,201GrantAmt
DescSince the launch of the Silverstein Foundation in March of 2017, it has funded over 30 grants, received donations from over 1000 donors and supported 7 different therapeutic approaches, including autophagy, antisense oligonucleotides, gene therapy, alpha synuclein degraders, glucocerebrosidase activators, substrate reduction therapy, and autologous induced pluripotent stem cells to accelerate research and clinical trials to bring new therapeutic options to patients. SEE SCHEDULE O.Desc
Total Program Service Expenses$848,201TotalProgramServiceExpensesAmt
Described In Section501c3Yes (true)DescribedInSection501c3Ind
Schedule B RequiredYes (true)ScheduleBRequiredInd
Political Campaign ActyfalsePoliticalCampaignActyInd
Lobbying ActivitiesfalseLobbyingActivitiesInd
Subject To Proxy TaxfalseSubjectToProxyTaxInd
Donor Advised FundfalseDonorAdvisedFundInd
Conservation EasementsfalseConservationEasementsInd
Collections Of ArtfalseCollectionsOfArtInd
Credit CounselingfalseCreditCounselingInd
Donor Rstr Or Quasi EndowmentsfalseDonorRstrOrQuasiEndowmentsInd
Report Land Building EquipmentfalseReportLandBuildingEquipmentInd
Report Investments Other SecYes (true)ReportInvestmentsOtherSecInd
Report Program Related InvstfalseReportProgramRelatedInvstInd
Report Other AssetsfalseReportOtherAssetsInd
Report Other LiabilitiesfalseReportOtherLiabilitiesInd
Include FIN48 FootnotefalseIncludeFIN48FootnoteInd
Independent Audit Fincl StmtYes (true)IndependentAuditFinclStmtInd
Consolidated Audit Fincl StmtfalseConsolidatedAuditFinclStmtInd
School OperatingfalseSchoolOperatingInd
Foreign OfficefalseForeignOfficeInd
Foreign ActivitiesfalseForeignActivitiesInd
More Than5000 K To OrgfalseMoreThan5000KToOrgInd
More Than5000 K To IndividualsfalseMoreThan5000KToIndividualsInd
Professional FundraisingfalseProfessionalFundraisingInd
Fundraising ActivitiesfalseFundraisingActivitiesInd
Gaming ActivitiesfalseGamingActivitiesInd
Operate HospitalfalseOperateHospitalInd
Grants To OrganizationsYes (true)GrantsToOrganizationsInd
Grants To IndividualsfalseGrantsToIndividualsInd
Schedule J RequiredfalseScheduleJRequiredInd
Tax Exempt BondsfalseTaxExemptBondsInd
Engaged In Excess Benefit TransfalseEngagedInExcessBenefitTransInd
PY Excess Benefit TransfalsePYExcessBenefitTransInd
Loan OutstandingfalseLoanOutstandingInd
Grant To Related PersonfalseGrantToRelatedPersonInd
Business Rln With Org MemfalseBusinessRlnWithOrgMemInd
Business Rln With Fam MemfalseBusinessRlnWithFamMemInd
Business Rln With35 Ctrl EntfalseBusinessRlnWith35CtrlEntInd
Deductible Non Cash ContrifalseDeductibleNonCashContriInd
Deductible Art ContributionfalseDeductibleArtContributionInd
Terminate OperationsfalseTerminateOperationsInd
Partial LiquidationfalsePartialLiquidationInd
Disregarded EntityfalseDisregardedEntityInd
Related EntityfalseRelatedEntityInd
Related Organization Ctrl EntfalseRelatedOrganizationCtrlEntInd
Trnsfr Exmpt Non Chrtbl Rltd OrgfalseTrnsfrExmptNonChrtblRltdOrgInd
Activities Conducted PrtshpfalseActivitiesConductedPrtshpInd
Schedule O RequiredfalseScheduleORequiredInd
IRP Document1IRPDocumentCnt
IRP Document W2 G0IRPDocumentW2GCnt
Employee0EmployeeCnt
Unrelated Bus Incm Over LimitfalseUnrelatedBusIncmOverLimitInd
Foreign Financial AccountfalseForeignFinancialAccountInd
Prohibited Tax Shelter TransfalseProhibitedTaxShelterTransInd
Taxable Party NotificationfalseTaxablePartyNotificationInd
Nondeductible ContributionsfalseNondeductibleContributionsInd
Quid Pro Quo ContributionsfalseQuidProQuoContributionsInd
Rcv Fnds To Pay Prsnl Bnft CntrctfalseRcvFndsToPayPrsnlBnftCntrctInd
Pay Premiums Prsnl Bnft CntrctfalsePayPremiumsPrsnlBnftCntrctInd
Indoor Tanning ServicesfalseIndoorTanningServicesInd
Subj To Tax Rmnrtn Ex Prcht PymtfalseSubjToTaxRmnrtnExPrchtPymtInd
Subject To Excs Tax Net Invst IncfalseSubjectToExcsTaxNetInvstIncInd
Info In Schedule O Part VIYes (X)InfoInScheduleOPartVIInd
Governing Body Voting Members3GoverningBodyVotingMembersCnt
Independent Voting Member3IndependentVotingMemberCnt
Family Or Business RlnYes (true)FamilyOrBusinessRlnInd
Delegation Of Mgmt DutiesfalseDelegationOfMgmtDutiesInd
Change To Org DocumentsfalseChangeToOrgDocumentsInd
Material Diversion Or MisusefalseMaterialDiversionOrMisuseInd
Members Or StockholdersfalseMembersOrStockholdersInd
Election Of Board MembersfalseElectionOfBoardMembersInd
Decisions Subject To ApprovafalseDecisionsSubjectToApprovaInd
Minutes Of Governing BodyYes (true)MinutesOfGoverningBodyInd
Minutes Of CommitteesYes (true)MinutesOfCommitteesInd
Officer Mailing AddressfalseOfficerMailingAddressInd
Local ChaptersfalseLocalChaptersInd
Form990 Provided To Gvrn BodyYes (true)Form990ProvidedToGvrnBodyInd
Conflict Of Interest PolicyYes (true)ConflictOfInterestPolicyInd
Annual Disclosure Covered PrsnYes (true)AnnualDisclosureCoveredPrsnInd
Regular Monitoring EnfrcYes (true)RegularMonitoringEnfrcInd
Whistleblower PolicyfalseWhistleblowerPolicyInd
Document Retention PolicyfalseDocumentRetentionPolicyInd
Compensation Process CEOfalseCompensationProcessCEOInd
Compensation Process OtherfalseCompensationProcessOtherInd
Investment In Joint VenturefalseInvestmentInJointVentureInd
States Where Copy Of Return Is FldNYStatesWhereCopyOfReturnIsFldCd
Upon RequestYes (X)UponRequestInd

Books In Care Of Detail BooksInCareOfDetail

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PersonJONATHAN T SILVERSTEINPersonNm
Phone9175198108PhoneNum

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Address Line111 RIVERSIDE DRIVE APT PH-W2AddressLine1Txt
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State AbbreviationNYStateAbbreviationCd
ZIP10023ZIPCd
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No Listed Persons CompensatedYes (X)NoListedPersonsCompensatedInd

Form990 Part VII Section A Form990PartVIISectionAGrp (3 entries)

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JONATHAN SILVERSTEIN
PRESIDENT / SECRETARY2.00.0Yes (X)Yes (X)$0$0$0
NATALIE SILVERSTEIN
VICE PRESIDENT / TREASURER1.00.0Yes (X)Yes (X)$0$0$0
GEOFFREY LEVIN
BOARD MEMBER1.00.0Yes (X)$0$0$0
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Total Comp Greater Than150 KfalseTotalCompGreaterThan150KInd
Compensation From Other SrcsfalseCompensationFromOtherSrcsInd
Cntrct Rcvd Greater Than100 K0CntrctRcvdGreaterThan100KCnt
All Other Contributions$379,686AllOtherContributionsAmt
Total Contributions$379,686TotalContributionsAmt
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Exclusion$49,600ExclusionAmt

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Total Revenue TotalRevenueGrp

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Total Revenue Column$430,928TotalRevenueColumnAmt
Exclusion$51,242ExclusionAmt
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Info In Schedule O Part IXYes (X)InfoInScheduleOPartIXInd

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DescDUES AND SUBSCRIPTIONSDesc
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FieldValueIRS element (for citing)
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Method Of Accounting AccrualYes (X)MethodOfAccountingAccrualInd
Accountant Compile Or ReviewfalseAccountantCompileOrReviewInd
FS AuditedYes (true)FSAuditedInd

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Audit CommitteefalseAuditCommitteeInd
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Schedule A IRS990ScheduleA

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Public Organization170Yes (X)PublicOrganization170Ind

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Current Tax Year$379,686CurrentTaxYearAmt
Total$7,196,734TotalAmt

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Total Calendar Year170 TotalCalendarYear170Grp

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Current Tax Year Minus3 Years$0CurrentTaxYearMinus3YearsAmt
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Current Tax Year Minus1 Year$599,990CurrentTaxYearMinus1YearAmt
Current Tax Year$379,686CurrentTaxYearAmt
Total$7,196,734TotalAmt
FieldValueIRS element (for citing)
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Public Support Total170$1,957,523PublicSupportTotal170Amt

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Current Tax Year Minus1 Year$61,051CurrentTaxYearMinus1YearAmt
Current Tax Year$49,600CurrentTaxYearAmt
Total$125,293TotalAmt

Unrelated Business Net Incm170 UnrelatedBusinessNetIncm170Grp

FieldValueIRS element (for citing)
Total$0TotalAmt

Other Income170 OtherIncome170Grp

FieldValueIRS element (for citing)
Total$0TotalAmt
FieldValueIRS element (for citing)
Total Support$7,322,027TotalSupportAmt
First5 Years170Yes (X)First5Years170Ind

Schedule B IRS990ScheduleB

Contributor Information ContributorInformationGrp

FieldValueIRS element (for citing)
ContributorRESTRICTEDContributorNum

Contributor Business Name ContributorBusinessName

FieldValueIRS element (for citing)
Business Name Line1RESTRICTEDBusinessNameLine1

Contributor US Address ContributorUSAddress

FieldValueIRS element (for citing)
Address Line1RESTRICTEDAddressLine1
Address Line2RESTRICTEDAddressLine2
CityRESTRICTEDCity
StateRESTRICTEDState
ZIP CodeRESTRICTEDZIPCode
FieldValueIRS element (for citing)
Total ContributionsRESTRICTEDTotalContributionsAmt

Schedule D IRS990ScheduleD

FieldValueIRS element (for citing)
Art Public Exhibition AmountsArtPublicExhibitionAmountsGrp
Held Works ArtHeldWorksArtGrp
CY Minus3 Yr Endwmt FundCYMinus3YrEndwmtFundGrp
CY Minus4 Yr Endwmt FundCYMinus4YrEndwmtFundGrp
LandLandGrp
BuildingsBuildingsGrp
Leasehold ImprovementsLeaseholdImprovementsGrp
EquipmentEquipmentGrp
Other Land BuildingsOtherLandBuildingsGrp
Financial DerivativesFinancialDerivativesGrp
Closely Held Equity InterestsCloselyHeldEquityInterestsGrp
Total Book Value Securities$0TotalBookValueSecuritiesAmt
Footnote TextYes (X)FootnoteTextInd
Total Rev Etc Audited Fincl Stmt$1,000,747TotalRevEtcAuditedFinclStmtAmt
Net Unrealized Gains Invst$569,819NetUnrealizedGainsInvstAmt
Revenue Not Reported$569,819RevenueNotReportedAmt
Revenue Subtotal$430,928RevenueSubtotalAmt
Total Revenue Per Form990$430,928TotalRevenuePerForm990Amt
Tot Expns Etc Audited Fincl Stmt$905,300TotExpnsEtcAuditedFinclStmtAmt
Expenses Subtotal$905,300ExpensesSubtotalAmt
Total Expenses Per Form990$905,300TotalExpensesPerForm990Amt

Supplemental Information Detail SupplementalInformationDetail

FieldValueIRS element (for citing)
Form And Line ReferenceSchedule D, Part X, Line 2FormAndLineReferenceDesc
ExplanationUncertain tax positions The Foundation is exempt from federal income tax under Section 501(c)(3). Accounting standards prescribe a recognition threshold and measurement attribute for the financial statement recognition and measurement of a tax position taken or expected to be taken in a tax return. These standards also provide guidance on de-recognition of tax benefits, classification on the balance sheet, interest and penalties, accounting in interim periods, disclosure, and transition. The Foundation has evaluated any uncertain tax positions and related income tax contingencies and determined uncertain positions, if any, are not material to the financial statements. Penalties and interest assessed by income taxing authorities are included in operating expenses, if incurred. Tax Returns are generally subject to examination by federal and state taxing authorities for three years.ExplanationTxt

Schedule I IRS990ScheduleI

FieldValueIRS element (for citing)
Grant Records MaintainedYes (true)GrantRecordsMaintainedInd

Recipient Table RecipientTable (5 entries)

Address Line1USAddress/AddressLine1TxtCityUSAddress/CityNmState AbbreviationUSAddress/StateAbbreviationCdZIPUSAddress/ZIPCdRecipient EINRecipientEINCash GrantCashGrantAmtNon Cash AssistanceNonCashAssistanceDescPurpose Of GrantPurposeOfGrantTxt
Chamishi Therapeutics Inc
711 Dimmeydale DriveDeerfieldIL60015352669722$375,001N/ARESEARCH
ARVINAS INC
5 SCIENCE PARKNEW HAVENCT06511463139663$50,000N/ARESEARCH
E SCAPE BIO INC
4000 Shoreline CTSan FranciscoCA94080474517216$200,000N/ARESEARCH
ASPEN NEUROSCIENCE INC
10835 Road to the CureSan DiegoCA92121831312969$191,200N/ARESEARCH CH
Q STATE BIOSCIENCES
179 Sidney StCambridgeMA02139462469775$32,000N/ARESEARCH
FieldValueIRS element (for citing)
Total501c3 Org0Total501c3OrgCnt
Total Other Org5TotalOtherOrgCnt

Supplemental Information Detail SupplementalInformationDetail (2 entries)

Form And Line ReferenceFormAndLineReferenceDescExplanationExplanationTxt
Schedule I, Line 1The Silverstein Foundation for Parkinsons with GBA maintains records to substantiate the funding amount, eligibility criteria and selection criteria used to award the grants. A Grant Contracting Process Summary provides detailed instructions and guidance for the Board and Scientific Advisory Board (SAB) as they seek new, cutting-edge therapeutic approaches for treating and preventing Parkinsons Disease in GBA mutation carriers. The SAB, which guides decision making in the selection process, is comprised of eleven (11) world renowned researchers and drug-developers. They are able to rapidly comb through GBA-related research to advance our goals and determine which grants shall be awarded. The Grant Contracting Process outlines the steps the Foundation takes to substantiate amounts and eligibility as follows; Primary Investigators (PI's) are asked to submit a detailed research plan and complete milestone and budget templates which are reviewed by Foundation staff and SAB members. Budget justification may be required. For private companies, high-level financial documents are requested in order to provide confirmation that the company has financial stability throughout the duration of the grant and beyond. Once all documents are received from grantee, internal review by all scientists ensures that all requests and goals are appropriate. A contract template, which includes payment schedule, is completed once all documents have been vetted by internal staff. A payment schedule is determined and payments are based upon milestones and deliverables being met. Clear go/no-go points for the research are required. Final executed contract, including budget and milestones are signed by the Foundation and the grantee, and are kept on file. Foundation personnel are assigned to oversee the progress of the grant, both scientifically and administratively. Progress updates, check-ins and reporting requirements are outlined and agreed upon in the contract and are monitored closely by personnel.
Schedule I, Line 2Describe the Foundation's procedures for monitoring the use of grant funds. The Silverstein Foundation for Parkinson's with GBA maintains a rigorous grant management process which involves the following steps: Identify point of contact (POC) internally and communicate this to grantee. Inform grantee that they will be in touch with POC proactively on: - First month progress on recruitment and hires (clinical grant) - Monthly progress on recruitment (clinical grant) - Scheduling a three (3) month call, midpoint assessment call and final assessment meeting/call. - Submit midpoint report and final report to the POC progress against milestones. Payments will only be released if milestones are met. Grantee will need to stay in touch to share updates. Adjust payments if milestones are delayed. If work cannot continue, modification of work or early termination of grant would be required. Upon confirmation that payment can be sent, inform Foundation Treasurer (Natalie Silverstein) three (3) days in advance to issue payment. Share grantee name, amount and bank information. Track information in grants tracker, payment tab. During midpoint and final report submission, ensure all high-level data, findings and results are shared in written form, even if grantee plans to share information via phone or in person during assessment meeting. Foundation shall save all reports and final presentations in grantee's file as "reports & results".

Schedule O IRS990ScheduleO

Supplemental Information Detail SupplementalInformationDetail (2 entries)

Form And Line ReferenceFormAndLineReferenceDescExplanationExplanationTxt
Form 990, Part III, LINE 1, Organization's missionCONTINUE FROM PART III: WE AGGRESSIVELY SEEK OUT NEW CUTTING EDGE THERAPEUTIC APPROACHES TREATING AND PREVENTING PARKINSON'S IN GBA MUTATION CARRIERS. THROUGH CLINICIANS, SCIENTISTS AND BIOTECH COMPANIES, WE SEEK TO ACCELERATE RESEARCH AND CLINICAL TRIALS IN AN EFFORT TO RAPIDLY BRING NEW THERAPEUTIC OPTIONS TO PATIENTS. FORM 990, PART III, LINE 4a, PROGRAM SERVICES CONTINUE FROM PART III: THE FOUNDATION PREVIOUSLY FUNDED THE FOLLOWING INITIATIVES THAT CONTINUE TO ADVANCE THE MISSION OF THE ORGANIZATION: Prevail Therapeutics, a company that the Foundation started with Asa Abeliovich, raised $200 million via private and public financing. Prevail recently announced that enrollment in the PR001 Phase 1/2 PROPEL clinical trial is progressing, patient dosing continues, and the Company is hopeful that it will remain on track to report interim data on a subset of patients in the second half of 2020. Aspen Neuroscience, which was spun out of Scripps Institute and the lab of world-renowned stem cell researcher Dr. Jean Loring, raised more than $70 million to study autologous stem cell approaches. FURTHER, THE FOUNDATION LAUNCHED THE FOLLOWING NEW INITIATIVES DURING 2019: During the third quarter of 2019, Vanqua Bio was launched, based on Foundation-funded research being conducted in the laboratory of Dr. Dimitri Krainc at Northwestern University. The company is focused on developing small molecule modulators of lysosomal targets that have genetic linkages to GBA PD. In September 2019, together with Q-State Biosciences, the Foundation launched Chamishi Therapeutics, a new drug discovery and development company focused on neurodegenerative diseases and other related disorders. The partnership will combine The Silverstein Foundation's deep scientific knowledge base with Q-State's precision medicine platform, disease-relevant cellular assays, and ASO (antisense-oligonucleotide) design capabilities. Chamishi is led by Jim Sullivan, former Vice President of Pharmaceutical Discovery at AbbVie.
form 990, Part VI, LINE 2, Family/Business RelationshipDIRECTORS JONATHAN SILVERSTEIN AND NATALIE SILVERSTEIN HAVE A FAMILY RELATIONSHIP. Form 990, Part VI, line 11, Form 990 Review The Form 990 is prepared, using information provided by the Foundation, by an independent accounting firm. the 990, as will be filed with the IRS, is reviewed by the board prior to its filing WITH THE INTERNAL REVENUE SERVICE. FORM 990, PART VI, LINE 12, CONFLICT OF INTEREST THE FOUNDATION HAS A CONFLICT OF INTEREST POLICY IN PLACE. (A) If the Foundation has multiple directors, a director who is directly or indirectly a party to a transcation with the foundation (an "interested director") shall disclose the material facts of the transaction and his or her interest in or relationship to such transaction to the Board of Directors and to any committee of the Board considering such transaction prior to any action by the Board or such committee to authorize, approve or ratify such transaction. A director is "indirectly" a party to a transaction if the entity which is a party is an entity in which the director has a material financial interest or of which the director is an officer, director or general partner. (b) The transaction shall be approved in good faith by the Board of Directors or a committee of the Board by the affirmative vote of: (i) a majority of the disinterested directors; or (ii) a majority of all the directors on the Board or committee after deciding that the transaction is fair to the Foundation as of the time it is authorized by the Board or committee. The presence of an interested director or of a director who is otherwise not disinterested may be counted in determining whether a quorum of the Board of Directors or a committee of the Board is present. The Board of Directors may in its discretion adopt other procedures as the Board determines is appropriate to address conflicts of interest.

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