Patents
US 9739734 B2: Methods and systems of detecting exocytosis of a target molecule from a population of cells
- Granted
- 2017-08-22
- Filed
- 2014-05-12 application 14889568
- Type
- Utility · 8 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
A method of detecting exocytosis of a target molecule from a population of cells derived from a human subject, includes applying first and second electrical signals, each having a respective frequency, across the population of cells. Each of the first and second electrical signals being either an alternating current or an alternating voltage. The method includes measuring a first voltage change if the first electrical signal is an alternating current or measuring a first current change if the first electrical signal is an alternating voltage, and measuring a second voltage change if the second electrical signal is an alternating current or measuring a second current change if the second electrical signal is an alternating voltage. The method includes determining an electrical impedance of the population of cells, a change in that impedance indicating an amount of the target molecule released from the population of cells.
Source: PVGPATDIS, file of 2026-04-10 (ipg170822.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| THE MARINE BIOLOGICAL LABORATORY 9 patents | US company or organization | Woods Hole, MA | The Marine Biological Laboratory State business registration EXACT high confidence: identical full name and state MARINE BIOLOGICAL LABORATORY Federal lobbying client FUZZY medium confidence: same name (legal endings aside) and state MARINE BIOLOGICAL LABORATORY Nonprofit FUZZY medium confidence: same name (governing-board words and legal endings aside) and state | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Mark Alan Messerli | Brookings, SD | 1 | PVGPATDIS, file of 2026-04-10 | |
| Emma Heart | Tampa, FL | 1 | PVGPATDIS, file of 2026-04-10 | |
| Munan Xu | East Falmouth, MA | 1 | PVGPATDIS, file of 2026-04-10 | |
| Shanta Menon Messerli | Sioux Falls, SD | 1 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| G01N | Investigating or analysing materials by determining their chemical or physical properties | G01N27/026 | PVGPATDIS, file of 2026-04-10 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K35/39 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2017-06-15 | Assignment Assignment of assignor's interest | HEART, EMMA signed 2014-04-30 MESSERLI, MARK ALAN signed 2014-04-30 XU, MUNAN signed 2014-04-30 MESSERLI, SHANTA MENON signed 2014-05-01 | THE MARINE BIOLOGICAL LABORATORY WOODS HOLE, MA | 42721/4 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.