Patents
US 9340550 B2: Methods for one-pot N-demethylation/N-functionalization of morphine and tropane alkaloids
- Granted
- 2016-05-17
- Filed
- 2015-01-30 application 14609612
- Type
- Utility · 36 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present invention provides a method for the N-demethylation and N-functionalization of an N-methylated heterocycle such as a morphine alkaloid or tropane alkaloid. The method comprises reacting the heterocycle with an functionalization agent in the presence of a transition metal catalyst in air or in the presence of an oxidant.
Source: PVGPATDIS, file of 2026-04-10 (ipg160517.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Brock University 27 patents | Foreign company or organization | St. Catharines, CA | Brock University College or university EXACT medium confidence: identical full name, one of each nationally BROCK UNIVERSITY Nonprofit EXACT medium confidence: identical full name, one of each nationally | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Tomas Hudlicky | St. Catharines, CA | 17 | PVGPATDIS, file of 2026-04-10 | |
| Robert James Carroll | Maidstone, GB | 6 | PVGPATDIS, file of 2026-04-10 | |
| Hannes Leisch | Neumarkt am Wallersee, AT | 6 | PVGPATDIS, file of 2026-04-10 | |
| Ales Machara | Rakovník, CZ | 10 | PVGPATDIS, file of 2026-04-10 | |
| Lukas Werner | Kadaň, CZ | 10 | PVGPATDIS, file of 2026-04-10 | |
| Mary Ann Endoma-Arias | Quezon, PH | 7 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07D | Heterocyclic compounds | C07D489/12 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2015-03-03 | Assignment Assignment of assignor's interest | CARROLL, ROBERT JAMES signed 2011-08-24 ENDOMA-ARIAS, MARY ANN signed 2011-08-24 HUDLICKY, TOMAS signed 2011-08-24 MACHARA, ALES signed 2011-08-24 WERNER, LUKAS signed 2011-08-29 LEISCH, HANNES signed 2011-08-30 | BROCK UNIVERSITY ST. CATHARINES, ONTARIO | 35071/479 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.